Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]
, 2017 We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann +5 more
core +2 more sources
Comparison of In Vitro Activities of the New Triazole SCH56592 and the Echinocandins MK-0991 (L-743,872) and LY303366 against Opportunistic Filamentous and Dimorphic Fungi and Yeasts [PDF]
, 1998 Ana Espinel‐Ingroff
openalex +1 more source
Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance. [PDF]
, 2016 The fungal pathogen Candida glabrata has emerged as a major health threat since it readily acquires resistance to multiple drug classes, including triazoles and/or echinocandins.
Alexander, B.D. +12 more
core +1 more source
Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]
, 2020 There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus +8 more
core +1 more source
Therapeutic Effects of Water-Soluble Echinocandin Compounds on Pneumocystis Pneumonia in Mice [PDF]
, 1998 Takahisa Furuta +5 more
openalex +1 more source
In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi [PDF]
, 2013 The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant species of Aspergillus section Flavi, including those of different phylogenetic clades of A.
Cano, Josep +4 more
core +2 more sources
In vitro antifungal activity of FK463, a new water-soluble echinocandin-like lipopeptide [PDF]
, 2000 Hiroshige Mikamo +2 more
openalex +1 more source
Echinocandins for Pneumocystis jirovecii pneumonia in non-HIV patients: A case report.
Experimental and Therapeutic Medicine, 2018 For the past two decades, echinocandins have shown prophylactic and therapeutic efficacy in patients with Pneumocystis jirovecii pneumonia (PJP), due to their ability to inhibit the synthesis of β-1, 3-glucan, a major component of the cell wall of P ...
Hui-bin Huang, Jing-Min Peng, B. Du
semanticscholar +1 more source
3 Biotech, 2019 Anidulafungin, a new class of antifungal agent used for the treatment of chronic fungal infections, is derived from Echinocandin B nucleus, an intermediate metabolite of Echinocandin B produced by Aspergillus nidulans. The enzyme acylase plays a key role in the bioconversion of Echinocandin B to Echinocandin B nucleus.
J. Savitha +5 more
openaire +3 more sources
The Effect of the Echinocandin Analogue Caspofungin on Cell Wall Glucan Synthesis byCryptococcus neoformans [PDF]
, 2000 Marta Feldmesser +3 more
openalex +1 more source