Results 51 to 60 of about 21,210 (293)
The Paradoxical Effect of Echinocandins in Aspergillus fumigatus Relies on Recovery of the β-1,3-Glucan Synthase Fks1 [PDF]
Veronika Loiko, Johannes Wagener
openalex +2 more sources
Echinocandins as Biotechnological Tools for Treating Candida auris Infections
Candida auris has been reported in the past few years as an invasive fungal pathogen of high interest. Its recent emergence in healthcare-associated infections triggered the efforts of researchers worldwide, seeking additional alternatives to the use of ...
E. Cândido+3 more
semanticscholar +1 more source
Treatment of Aspergillosis. [PDF]
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
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First hospital outbreak of the globally emerging Candida auris in a European hospital [PDF]
Background: Candida auris is a globally emerging multidrug resistant fungal pathogen causing nosocomial transmission. We report an ongoing outbreak of C. auris in a London cardio-thoracic center between April 2015 and July 2016.
Abdolrasouli, A+11 more
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“Illuminating” Echinocandins’ Mechanism of Action [PDF]
Tracking caspofungin accumulation is key for a better understanding of drug resistance in pathogenic fungi.
Boon Shing Loh, Wee Han Ang
openaire +3 more sources
Candida auris was first reported in an ear swab from Japan in 2009; it then promptly spread over five continents and turned into a global nosocomial problem. The main challenges faced by many researchers are the mis-identification by conventional methods
M. Vatanshenassan+7 more
semanticscholar +1 more source
Bloodstream yeast infections: a 15-month survey [PDF]
A 15-month survey of 412 bloodstream yeast isolates from 54 Belgian hospitals was undertaken. Candida albicans was the most common species (47.3%) followed by C. glabrata (25.7%), C. parapsilosis (8.0%), C. tropicalis (6.8%) and Saccharomyces cerevisiae (
Detandt, M+3 more
core +1 more source
The importance of subclasses of chitin synthase enzymes with myosin-like domains for the fitness of fungi [PDF]
Acknowledgements TG and CF are funded by FEDER funds through the Operational Programme Competitiveness Factors – COMPETE and national funds by FCT – Foundation for Science and Technology under the strategic project UID/NEU/04539/2013. C.F. is a recipient
Fernandes, Chantal+2 more
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Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata
Candida glabrata has thoroughly adapted to successfully colonize human mucosal membranes and survive in vivo pressures. prior to and during antifungal treatment. Out of all the medically relevant Candida species, C.
K. Healey, D. Perlin
semanticscholar +1 more source
Cdc14 phosphatase contributes to cell wall integrity and pathogenesis in Candida albicans
The Cdc14 phosphatase family is highly conserved in fungi. In Saccharomyces cerevisiae, Cdc14 is essential for down-regulation of cyclin-dependent kinase activity at mitotic exit.
Kedric L. Milholland+15 more
doaj +1 more source