Results 111 to 120 of about 324,854 (299)
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair
Advanced Healthcare Materials, EarlyView.An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret +6 more
wiley +1 more source
TGF-β1 tilted the balance of ECM and MMP gene expression in favor of ECM.
, 2013 (A) A comparison of the total ECM (includes fibronectin, collagen and proteoglycan genes) vs. total MMP expression (includes MMP-2, -3, -14 and -16 genes) illustrates that TGF-β1 caused dose-dependent increases in overall ECM transcription, but not MMP ...
Youssef M. Farhat (295089) +6 more
core +1 more source
International Journal of Nanomedicine, 2020 Enrui Chen,1,* Shangcong Han,1,* Bo Song,2 Lisa Xu,1 Haicheng Yuan,2 Mingtao Liang,3 Yong Sun1 1Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, People’s Republic of China; 2Department of Neurology, Qingdao Central ...
Chen E +6 more
doaj
Advanced Healthcare Materials, EarlyView.Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
wiley +1 more source
Lung ECM solution preparation and delivery.
, 2017 Porcine lung (A) was sliced and treated with SDS (B) to obtain decellularized ECM (C). The lung ECM was enzymatically digested with pepsin (D), followed by neutralization and dilution, as well as filtration through a 1.2 μm filter to yield the ECM ...
Yi Hong (32844) +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones +14 more
wiley +1 more source
, 2017 Mit der ganzheitlichen Strategie des Enterprise Content Management (ECM) werden alle Dokumente eines Unternehmens verwaltet und organisiert. Durch den Einsatz geeigneter ECM Werkzeuge erhalten Unternehmen zum Beispiel Unterstützung beim effizienten ...
Stich, Volker +3 more
core
, 2019 Equally sized ECM pieces were added to HUVECs seeded in a 96-well plate and cell number was measured with MTS assay 48h after incubation. Control consists of cells without added ECM pieces. n = 5 in duplicates for all groups.
Niklas Bergh (182247) +6 more
core +1 more source
Multiscale modelling shows how cell-ECM interactions impact ECM fibre alignment and cell detachment
The extracellular matrix (ECM) is a dynamic network structure that surrounds, supports, and influences cell behaviour. It facilitates cell communication and plays an important role in cell functions such as growth and migration.
Alarcón, Tomás +4 more
core +3 more sources