Results 81 to 90 of about 277,895 (300)

Anti-vascular endothelial growth factor treatment in diabetic macular edema

open access: yesTherapeutics and Clinical Risk Management, 2016
Moosang KimDepartment of Ophthalmology, School of Medicine, Kangwon National University, Chuncheon, KoreaWe read with great interest the article titled “Clinical effects and safety of treating diabetic macular edema with intravitreal injection of ...
Kim M
doaj  

Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome in a Chronic Hemodialysis Patient

open access: yesCase Reports in Medicine, 2012
A 75-year-old male who was undergoing chronic hemodialysis developed abrupt-onset pitting edema and pain in the dorsum of both hands and feet. Biochemical analysis disclosed increased C-reactive protein, and negative rheumatoid factor and antinuclear ...
Shunsuke Yamada   +4 more
doaj   +1 more source

Shape Memory Microneedle to Prevent Risks of Reproductive Hormone Therapy by Switching Sustained to Burst Release Under a Single Transdermal Insertion

open access: yesAdvanced Functional Materials, EarlyView.
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho   +8 more
wiley   +1 more source

Empirical Valence Bond Simulations of the Chemical Mechanism of ATP to cAMP Conversion by Anthrax Edema Factor

open access: yes, 2016
The two-metal catalysis by the adenylyl cyclase domain of the anthrax edema factor toxin was simulated using the empirical valence bond (EVB) quantum mechanical/molecular mechanical approach.
Wei-Jen Tang (29088)   +2 more
core   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Binding of N-terminal fragments of anthrax edema factor (EFN) and lethal factor (LFN) to the protective antigen pore

open access: yes, 2008
Anthrax toxin consists of three different molecules: the binding component protective antigen (PA, 83 kDa), and the enzymatic components lethal factor (LF, 90 kDa) and edema factor (EF, 89 kDa).
Benz, Roland   +4 more
core   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen   +6 more
wiley   +1 more source

Sodium Alginate‐Based Submucosal Lifting Hydrogel for Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection

open access: yesAdvanced Healthcare Materials, EarlyView.
A biocompatible sodium alginate‐based hydrogel is developed as a next‐generation submucosal lifting agent intended for EMR and ESD. The optimized formulation exhibits a composition devoid of endotoxins, high viscosity, demonstrates reliable injectability, and ensures prolonged mucosal elevation.
Iram Maqsood   +9 more
wiley   +1 more source

Purification of Anthrax Edema Factor from Escherichia coli and Identification of Residues Required for Binding to Anthrax Protective Antigen

open access: yes, 2001
The structural gene for anthrax edema factor (EF) was expressed in Escherichia coli under the control of a powerful T5 promoter to yield the 89-kDa recombinant protein that reacted with anti-EF antibodies.
Bhatnagar, Rakesh   +5 more
core   +1 more source

Relationship between Macular Thickness and the Ratio of Vascular Endothelial Growth Factor to Its Soluble Receptor 1 in Non-Proliferative Diabetic Retinopathy

open access: yesمجله دانشکده پزشکی اصفهان, 2012
Background: The goal of this study was to determine the ratio of vascular endothelial growth factor (VEGF) to soluble VEGF receptor 1 (SVEGFR1) in aqueous humor of patients with non-proliferative diabetic retinopathy (NPDR).
Zahra Hasanpour   +4 more
doaj  

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