Results 91 to 100 of about 277,895 (300)
Advanced Robotics Research, EarlyView.Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin +3 more
wiley +1 more source
, 2013 The lethal toxin (LT) of Bacillus anthracis, composed of the protective antigen (PA) and the lethal factor (LF), plays an essential role in anthrax pathogenesis.
Behrens Christian K. +11 more
core +2 more sources
Advanced Science, EarlyView.ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu +15 more
wiley +1 more source
Methods and compositions relating to anthrax pathogenesis [PDF]
, 2023 The structures of Edema Factor alone and Edema Factor bound to calmodulin without substrate has been crystallized and its structure determined by x-ray crystallography. Based upon these crystal structures, a method assaying for inhibitors of infection by
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Clinical Ophthalmology, 2016 Patrick Oellers,1,2 Dilraj S Grewal,1,2 Sharon Fekrat1,2 1Duke Eye Center, Duke University Medical Center, 2Surgical Service, Durham Veterans Affairs Medical Center, Durham, NC, USA Abstract: For years, the standard of care for branch-retinal-vein ...
Oellers P, Grewal DS, Fekrat S
doaj
Specific risk factors among initial swelling sites of breast cancer-related lymphedema
Zhongguo kangfu lilun yu shijianObjective To explore the clinical characteristics and specific risk factors of breast cancer-related lymphedema (BCRL) patients with different initial swelling sites (chest wall, upper arm, forearm and hand).
XIE Na, LI Li, JIA Jie
doaj +1 more source
Advanced Science, EarlyView.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
Effect of Hydrostatic Factor on Ischemic Brain Edema
Neurologia medico-chirurgica, 1988 The development of ischemic cerebral edema was studied in terms of the intracranial hydrostatic factor. Adult mongrel cats underwent occlusion of the right middle cerebral artery via the transorbital approach to induce focal cerebral ischemia. Three hours after the arterial occlusion, hypertension was produced for 30 minutes. Based on the extent of the
openaire +3 more sources
Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis
Advanced Science, EarlyView.Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang +16 more
wiley +1 more source
Identification of Rab11 as a target of edema factor and dominant-negative mutants of anthrax lethal factor [PDF]
, 2013 Anthrax is a fatal disease caused by the spore-formulating bacterium, Bacillus anthracis. The potential for anthrax as a bioterrorist weapon raises concern, and is still common in the developing world.
Kurkciyan, Adrianne A.
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