Results 261 to 270 of about 219,266 (297)

Balancing Intrinsic and Extrinsic Factors in CD8⁺ T Cell Therapy. [PDF]

Immune Netw
Lee D, Lee Y.
europepmc   +1 more source

Dynamic regulation of BACH2 enhances CAR T cell function. [PDF]

Mol Ther Oncol
Chang TC, Warrington JM, Singh N.
europepmc   +1 more source

38-Marker Full-Spectrum Flow Cytometry Panel for the Comprehensive Profiling of γδ T Cells in Human Blood and Lymphoid Tissues. [PDF]

Eur J Immunol
Hamed M, Moreno-Vicencio D, Arsovski D, Farhat M, Sanders R, Mann E, Bennett A, Chevour P, Davey MS.   +8 more
europepmc   +1 more source

Memory Regulatory T Cells as a Biomarker of Early Type 1 Diabetes. [PDF]

Diabetes
Raineri D, Savastio S, Bellone S, Scotti L, Barbero-Mazzucca C, Cappellano G, Prodam F, Pozzi E, Rabbone I, Chiocchetti A.   +9 more
europepmc   +1 more source

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Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance

Annual Review of Immunology, 2004
The memory T cell pool functions as a dynamic repository of antigen-experienced T lymphocytes that accumulate over the lifetime of the individual. Recent studies indicate that memory T lymphocytes contain distinct populations of central memory (TCM) and effector memory (TEM) cells characterized by distinct homing capacity and effector function.
Sallusto F, Geginat J, Lanzavecchia A
openaire   +4 more sources

Memory CD4 T cells emerge from effector T-cell progenitors

Nature, 2008
A hallmark of adaptive immunity is the generation of memory T cells that confer long-lived, antigen-specific protection against repeat challenges by pathogens. Understanding the mechanisms by which memory T cells arise is important for rational vaccination strategies and improved therapeutic interventions for chronic infections and autoimmune disorders.
Laurie E, Harrington, Karen M, Janowski, James R, Oliver, Allan J, Zajac, Casey T, Weaver   +4 more
openaire   +2 more sources

Homeostasis of naı̈ve, effector and memory CD8 T cells

Current Opinion in Immunology, 2002
Homeostatic control of CD8 T cell populations is essential for defense against infectious pathogens. Our understanding of the mechanisms that control naïve, effector and memory T cell populations in the intact animal has increased significantly over the last several years. There have been some surprises.
Roman A, Tuma, Eric G, Pamer
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Local development of effector and memory T helper cells

Current Opinion in Immunology, 2007
Clonal evolution underpins all facets of adaptive immunity. In particular, antigen-specific helper T (Th) cell development is central to high-affinity B cell immunity and protective vaccination. Dendritic cell maturation and TCR affinity-based selection mechanisms control the recruitment and effective propagation of preferred antigen-specific Th cell ...
Nicolas, Fazilleau, Louise J, McHeyzer-Williams, Michael G, McHeyzer-Williams   +2 more
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The effector to memory transition of CD4 T cells

Immunologic Research, 2007
The small number of antigen-specific memory CD4 T cells surviving long-term after antigen or pathogen challenge are often characterized by a surprising degree of phenotypic and functional heterogeneity. We here propose that the immune system has evolved to express this diversity in memory T-cell populations, in order to provide flexibility in recall ...
K Kai, McKinstry, Tara M, Strutt, Susan L, Swain   +2 more
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Activation of naive, memory and effector T cells

Current Opinion in Immunology, 1994
An increased understanding of the types of T-cell subsets that exist in vivo, their relationships to one another, and how to identify and isolate them or effect their generation, has led to a comprehensive view of the antigen-presenting cells (APCs) which may be active and regulatory during the course of an immune response.
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