Results 1 to 10 of about 16,722 (158)

Efferocytosis: The Silent Guardian of Tissue Homeostasis and Cardiovascular Health [PDF]

Journal of Cardiovascular Development and Disease
Rapid and effective clearance of apoptotic cells, known as efferocytosis, is essential for maintaining tissue homeostasis. Efferocytosis removes apoptotic cells before the occurrence of membrane rupture from which the cell contents, often inflammatory ...
Wenting Peng, Yuhao Song, Shengxi Gu, Ye Zhu, Ying Li   +4 more
doaj   +2 more sources

Primed mesenchymal stem cells attenuate schistosomiasis fibrosis by enhancing macrophage subset switching and efferocytosis via Itgb2-Rac1 axis [PDF]

Cell Death Discovery
The pathological hallmark of schistosomiasis is egg-induced granulomatous inflammation and the subsequent fibrosis in the liver; and mesenchymal stem cells have been explored for the treatment of schistosomiasis fibrosis.
Junxia Lei, Yaojia Ren, Zebin Chen, Wanxian Huang, Meiyining Xu, Zhongdao Wu   +5 more
doaj   +2 more sources

Roles of efferocytosis in wound repair: Process, cells, and signals [PDF]

Genes and Diseases
Efficient clearance of apoptotic cells, termed efferocytosis, is essential for resolving excessive inflammation, promoting wound repair, and maintaining homeostasis.
Yilin Sun, Haiying Guo, Yang Bai, Jin Chen, Yuhong Li   +4 more
doaj   +2 more sources

Risk of pneumonia in obstructive lung disease : A real-life study comparing extra-fine and fine-particle inhaled corticosteroids [PDF]

, 2017
The study received institutional support from Teva Pharmaceuticals Europe B.V. Teva did not contribute either in part or in whole, to the collection, analysis, or interpretation of study data, manuscript writing, or the decision to submit the manuscript ...
Burden, Annie, Israel, Elliot, Martin, Richard, Postma, Dirkje, Price, David Brendan, Respiratory Effectiveness Group, Small Airways Study Group, Sonnappa, Samatha, Usmani, Omar S, van Aalderen, Wim   +8 more
core   +33 more sources

Macrophage COX2 Mediates Efferocytosis, Resolution Reprogramming, and Intestinal Epithelial RepairSummary

Cellular and Molecular Gastroenterology and Hepatology, 2022
Background and Aims: Phagocytosis (efferocytosis) of apoptotic neutrophils by macrophages anchors the resolution of intestinal inflammation. Efferocytosis prevents secondary necrosis and inhibits further inflammation, and also reprograms macrophages to ...
David Meriwether, Anthony E. Jones, Julianne W. Ashby, R. Sergio Solorzano-Vargas, Nasrin Dorreh, Shoreh Noori, Victor Grijalva, Andréa B. Ball, Margarita Semis, Ajit S. Divakaruni, Julia J. Mack, Harvey R. Herschman, Martin G. Martin, Alan M. Fogelman, Srinivasa T. Reddy   +14 more
doaj   +1 more source

Defective efferocytosis of vascular cells in heart disease

Frontiers in Cardiovascular Medicine, 2022
The efficient phagocytic clearance of dying cells and apoptotic cells is one of the processes that is essential for the maintenance of physiologic tissue function and homeostasis, which is termed “efferocytosis.” Under normal conditions, “find me” and ...
Bandana Singh, Kathryn Li, Kui Cui, Qianman Peng, Douglas B. Cowan, Da-Zhi Wang, Kaifu Chen, Hong Chen   +7 more
doaj   +1 more source

Efferocytosis in the Central Nervous System

Frontiers in Cell and Developmental Biology, 2021
The effective clearance of apoptotic cells is essential for maintaining central nervous system (CNS) homeostasis and restoring homeostasis after injury.
Jiayi Zhao, Weiqi Zhang, Tingting Wu, Hongyi Wang, Jialiang Mao, Jian Liu, Ziheng Zhou, Xianfeng Lin, Huige Yan, Qingqing Wang   +9 more
doaj   +1 more source

Efferocytosis and Its Role in Inflammatory Disorders

Frontiers in Cell and Developmental Biology, 2022
Efferocytosis is the effective clearance of apoptotic cells by professional and non-professional phagocytes. The process is mechanically different from other forms of phagocytosis and involves the localization, binding, internalization, and degradation ...
Yun Ge, Man Huang, Yong-ming Yao, Yong-ming Yao   +3 more
doaj   +1 more source

Identification of efferocytosis-related subtypes in gliomas and elucidating their characteristics and clinical significance

Frontiers in Cell and Developmental Biology, 2023
Introduction: Gliomas, the most prevalent tumors of the central nervous system, are known for their aggressive nature and poor prognosis. The heterogeneity among gliomas leads to varying responses to the same treatments, even among similar glioma types ...
Mengge Gao, Jinsheng Huang, Bo Yang, Qiong Liu, Miaoqing Luo, Biying Yang, Xujia Li, Xiaofang Liu   +7 more
doaj   +1 more source

Potential Mechanisms and Effects of Efferocytosis in Atherosclerosis

Frontiers in Endocrinology, 2021
Atherosclerosis (AS) is the main pathological basis for the development of cardio-cerebrovascular diseases. Abnormal accumulation of apoptotic and necrotic cells resulted in plaque enlargement, necrotic core formation and plaque rupture in AS.
Lili Wang, Lili Wang, Lili Wang, Hongxia Li, Hongxia Li, Hongxia Li, Yuhan Tang, Yuhan Tang, Yuhan Tang, Ping Yao, Ping Yao, Ping Yao   +11 more
doaj   +1 more source