Results 241 to 250 of about 90,161 (342)

Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus. [PDF]

PLoS Pathog
McGowen K, Funck T, Wang X, Zinga S, Wolf ID, Akusobi C, Denkinger CM, Rubin EJ, Sullivan MR.   +8 more
europepmc   +1 more source

Physiological characterisation of the efflux pump system of antibiotic-susceptible and multidrug-resistant Enterobacter aerogenes

, 2010
Ana Martins, Gabriella Spengler, Marta Martins, Liliana Rodrigues, Miguel Viveiros, Anne Davin‐Regli, Jacqueline Chevalier, Isabel Couto, Jean‐Marie Pagès, Leonard Amaral   +9 more
openalex   +2 more sources

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Effect of temperature on the activity of efflux pumps in selected species of human opportunistic bacterial pathogens. [PDF]

Mem Inst Oswaldo Cruz
Hurton D, Hleba L, Petrová J, Laho M, Koren J, Liptáková A.   +5 more
europepmc   +1 more source

Point Mutation Analysis of the Drug Efflux Pump MexB in Clinical Isolates of <i>Pseudomonas aeruginosa</i>

Seiji Yamasaki, Naoki Koga, Ryosuke Nakashima, Mitsuko Hayashi-Nishino, Kunihiko Nishino   +4 more
openalex   +2 more sources

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Whole-Genome Sequence Analysis to Assess Mutations in Efflux Pumps in <i>Mycobacterium tuberculosis</i>: The Influence in Drug Resistance. [PDF]

Microorganisms
Chimal-Muñoz M, Pérez-Martínez DE, Bermúdez Hernández GA, Mejía-Ponce PM, Licona-Cassani C, Muñiz-Salazar R, Montero H, Zenteno-Cuevas R.   +7 more
europepmc   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Human vaginal Lactobacillus Jensenii -derived (-)-Terpinen-4-ol restores antibiotic sensitivity by inhibiting efflux pumps in drug resistant E. coli and K. pneumoniae. [PDF]

Sci Rep
Nair VG, Unnikrishnan VK, Muralidharan N, Venkatathri BNS, Lowrence RC, Ybrd R, Narbhavi D, A A, N P, Nagarajan S.   +9 more
europepmc   +1 more source

A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...
Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn   +4 more
wiley   +1 more source