Studies on Novel Inhibitor of Mitotic Kinesin Eg5: A Validated Chemotherapeutic Target
長崎大学学位論文 [学位記番号]博(水・環)甲第53号 [学位授与年月日]令和元年9月20日 (2019-09-20)
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HPV16 entry requires dynein for minus-end transport and utilizes kinesin Kif11 for plus-end transport along microtubules during mitosis. [PDF]
Keiffer TR +7 more
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Application of Spindle Kinesin Eg5-Specific Inhibitors to C. elegans Kinesins
Kinesin superfamily motor proteins are ATP-driven molecular machines that hydrolyze ATP to move along microtubules and play pivotal roles in intracellular trafficking, spindle formation, and chromosome segregation. By converting chemical energy into mechanical work, these nanomachines drive essential physiological processes in both animal and plant ...
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The role of kinesin family members in hepatobiliary carcinomas: from bench to bedside. [PDF]
Zhao K, Li X, Feng Y, Wang J, Yao W.
europepmc +1 more source
Reversible and effective cell cycle synchronization method for studying stage-specific processes. [PDF]
Chen YL, Reddy S, Suzuki A.
europepmc +1 more source
Role and therapeutic potential of the NEDD4 family in breast cancer. [PDF]
Zhang X, Li S.
europepmc +1 more source
Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes. [PDF]
Farrell KC, Wang JT, Stearns T.
europepmc +1 more source
Advances of NAT10 in diseases: insights from dual properties as protein and RNA acetyltransferase. [PDF]
Xiao B +11 more
europepmc +1 more source
Natural Product Target Identification of Wheldone, a Fungal Metabolite, as a KIF11 Inhibitor in Ovarian Cancer Using the DiffPOP (Differential Protein Precipitation) Method. [PDF]
Khin M +14 more
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Spatio-temporal control of mitosis using light via a Plk1 inhibitor caged for activity and cellular permeability. [PDF]
von Glasenapp V +5 more
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