Results 41 to 50 of about 33,906 (210)
Adipokinetic hormone enhances nodule formation and phenoloxidase activation in adult locusts injected with bacterial lipopolysaccharide [PDF]
, 2003 Interactions between the locust endocrine and immune systems have been studied in vivo in relation to nodule formation and activation of the prophenoloxidase cascade in the haemolymph.
Chandrakant, S. +2 more
core +1 more source
S1R agonist modulates rat platelet eicosanoid synthesis and aggregation
Platelets, 2022 Sigma-1 receptor (S1R) is detected in different cell types and can regulate intracellular signaling pathways. S1R plays a role in the pathomechanism of diseases and the regulation of neurotransmitters. Fluvoxamine can bind to S1R and reduce the serotonin
Sándor Váczi +12 more
doaj +1 more source
Statistical Workflow for Feature Selection in Human Metabolomics Data. [PDF]
, 2019 High-throughput metabolomics investigations, when conducted in large human cohorts, represent a potentially powerful tool for elucidating the biochemical diversity underlying human health and disease.
Antonelli, Joseph +17 more
core +2 more sources
Journal of Lipid Research, 1994 Eicosanoids are oxidative derivatives of arachidonic acid. When produced in excessive amounts, many are proinflammatory and/or prothrombotic agents. N-3 polyunsaturated fatty acids (PUFA) have been used to attenuate tissue arachidonic acid (AA, 20:4 n-6)
B Li, C Birdwell, J Whelan
doaj +1 more source
Insects, 2021 Repat (=response to pathogen) is proposed for an immune-associated gene family from Spodoptera exigua, a lepidopteran insect. In this gene family, 46 members (Repat1–Repat46) have been identified. They show marked variations in their inducible expression
Md Tafim Hossain Hrithik +3 more
doaj +1 more source
Advanced Science, EarlyView.The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher +15 more
wiley +1 more source
Role of Oxylipins in the Inflammatory-Related Diseases NAFLD, Obesity, and Type 2 Diabetes
Metabolites, 2022 Oxygenated polyunsaturated fatty acids (oxylipins) are bioactive molecules established as important mediators during inflammation. Different classes of oxylipins have been found to have opposite effects, e.g., pro-inflammatory prostaglandins and anti ...
Mariya Misheva +2 more
doaj +1 more source
METHOD FOR MODULATING EICOSANOID MEDIATED IMMUNE RESPONSES IN ARTHROPODS [PDF]
, 2000 The invention is directed to compositions which alter the health of invertebrate organisms by affecting eicosanoid mediated immune responses, and methods of using the compositions.
Stanley, David W.
core +1 more source
Eicosapentaenoic acid induces DNA demethylation in carcinoma cells through a TET1-dependent mechanism [PDF]
, 2018 In cancer cells, global genomic hypomethylation is found together with localized hypermethylation of CpG islands within the promoters and regulatory regions of silenced tumor suppressor genes.
Billi, Monia +9 more
core +1 more source
Advanced Science, EarlyView.This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia +5 more
wiley +1 more source