Results 51 to 60 of about 21,935 (239)
British Journal of Clinical Pharmacology, EarlyView.Aim Ceftriaxone is a cephalosporin commonly used for the treatment of acute, severe infections; however, there are conflicting data on its disposition properties in children, making it a suitable case study for the evaluation of the appropriateness of extrapolation approaches based on exposure matching principles for paediatric patients and exploring ...
Daniel Valente Neves +7 more
wiley +1 more source
, 2020 Correlation, univariate and multivariate linear regression of sPLA2-IIA and eicosanoid metabolites and SIRS.
Yasmin Anum Mohd Yusof (8561865) +4 more
core +1 more source
Cells, 2022 High eosinophil (EOS) counts are a key feature of eosinophilic asthma. EOS notably affect asthmatic response by generating several lipid mediators. Mice have been utilized in hopes of defining new pharmacological targets to treat asthma.
Anne-Sophie Archambault +8 more
doaj +1 more source
A Green Protocol for the Deprotection of ortho‐Nitrobenzyl Esters and Ethers by UVA–LED Irradiation
Chemistry – A European Journal, EarlyView.This study presents a green and efficient photochemical protocol for the deprotection of ortho‐nitrobenzyl esters or ethers under mild conditions, using UVA‐LED irradiation in methanol. The broad applicability of the protocol was validated in the synthesis of a cytosolic phospholipase A2 inhibitor. ABSTRACT The removal of protecting groups in synthetic
Despoina Poikilidou +3 more
wiley +1 more source
Grasas y Aceites, 2016 The mediterranean diet (MD) reduced the risk of colorectal cancer (CRC), and olive oil, the primary source of fat in the MD, has also been found to have a protective effect. However, animals fed with oleic acid present a high number of intestinal tumours,
C. E. Storniolo, J. J. Moreno
doaj +1 more source
Frontiers in Endocrinology, 2023 BackgroundEicosanoids are a group of the oxygenated C20 polyunsaturated fatty acids and play crucial roles in mediating various insect physiological processes. Catalytic activity of phospholipase A2 (PLA2) provides an initial substrate, arachidonic acid (
Md Tafim Hossain Hrithik +2 more
doaj +1 more source
Food Chemistry International, EarlyView.The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi +2 more
wiley +1 more source
EicosaCell: An Imaging-Based Assay to Identify Spatiotemporal Eicosanoid Synthesis
, 2017 Acesso aberto em 20/04/2020 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774667/Eicosanoids are bioactive lipids derived from enzymatic metabolism of arachidonic acid via the cyclooxygenase (COX) and lipoxygenase (LOX) pathways. These lipids are newly
Christianne Bandeira-Melo +9 more
core +1 more source
Food Biomacromolecules, EarlyView.Abstract Functional foods have gained increasing attention for their capacity to promote health and reduce chronic‐disease risk beyond basic nutrition. Among plant‐based functional ingredients, pumpkin (Cucurbita spp.) and chia (Salvia hispanica L.) seeds are nutrient‐dense sources of proteins, unsaturated fatty acids, dietary fiber, tocopherols ...
Fatima Urooj +8 more
wiley +1 more source
A. phagocytophilum infection induces eicosanoid biosynthesis.
, 2016 (A) Heat map of deep sequencing analysis showing the expression of eicosanoid metabolism genes in murine BMDMs (1.5×107 cells) infected with A. phagocytophilum (MOI50) for 18 hours.
Fayyaz S. Sutterwala (260673) +18 more
core +1 more source