Results 31 to 40 of about 21,935 (239)

Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology1[S]

open access: yesJournal of Lipid Research, 2009
Eicosanoids have been implicated in a vast number of devastating inflammatory conditions, including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different eicosanoids have been identified, with many having potent bioactive ...
Matthew W. Buczynski   +2 more
doaj   +1 more source

the-enzymes-of-the-human-eicosanoid-pathway.pdf

open access: yes, 2018
Although there are a number of excellent reviews on various aspects of eicosanoid metabolism, this review was written to not only bring the subject up to date, but to do so in a highly comprehensive manner.
Roger Biringer (8324466)
core   +1 more source

Total synthesis of the endogenous inflammation resolving lipid resolvin D2 using a common lynchpin

open access: yesBeilstein Journal of Organic Chemistry, 2013
The total synthesis of the endogenous inflammation resolving eicosanoid resolvin D2 (1) is described. The key steps involved a Wittig reaction between aldehyde 5 and the ylide derived from phosphonium salt 6 to give enyne 17 and condensation of the same ...
John Li   +3 more
doaj   +1 more source

The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism

open access: yes, 1992
Eicosanoids, in particular prostaglandin E2 (PGE2), are potent inhibitors of a number of immune responses, including lymphocyte proliferation. We have previously shown that fatty acids, especially polyunsaturated fatty acids (PUFA), inhibit mitogen ...
Calder, P.C.   +2 more
core   +2 more sources

athar71/Eicosanoids_HFpEF: Version 1 for HFpEF Eicosanoid Paper

open access: yes, 2023
First Release for HFpEF Eicosanoid Project <p>This includes the functions for reading and preprocessing the metabolites data as well as the mediation analyses code.</p ...
Athar Roshandelpoor
core   +1 more source

Antithetic relationship of dietary arachidonic acid and eicosapentaenoic acid on eicosanoid production in vivo

open access: yesJournal of Lipid Research, 1994
Eicosanoids are oxidative derivatives of arachidonic acid. When produced in excessive amounts, many are proinflammatory and/or prothrombotic agents. N-3 polyunsaturated fatty acids (PUFA) have been used to attenuate tissue arachidonic acid (AA, 20:4 n-6)
B Li, C Birdwell, J Whelan
doaj   +1 more source

S1R agonist modulates rat platelet eicosanoid synthesis and aggregation

open access: yesPlatelets, 2022
Sigma-1 receptor (S1R) is detected in different cell types and can regulate intracellular signaling pathways. S1R plays a role in the pathomechanism of diseases and the regulation of neurotransmitters. Fluvoxamine can bind to S1R and reduce the serotonin
Sándor Váczi   +12 more
doaj   +1 more source

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

open access: yesAdvanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian   +9 more
wiley   +1 more source

Lipid body function in eicosanoid synthesis: An update

open access: yes, 2011
Eicosanoids (prostaglandins, leukotrienes and lipoxins) are signaling lipids derived from arachidonic acid metabolism that have important roles in physiological and pathological processes.
Melo, Christianne Bandeira   +7 more
core   +1 more source

Repat33 Acts as a Downstream Component of Eicosanoid Signaling Pathway Mediating Immune Responses of Spodoptera exigua, a Lepidopteran Insect

open access: yesInsects, 2021
Repat (=response to pathogen) is proposed for an immune-associated gene family from Spodoptera exigua, a lepidopteran insect. In this gene family, 46 members (Repat1–Repat46) have been identified. They show marked variations in their inducible expression
Md Tafim Hossain Hrithik   +3 more
doaj   +1 more source

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