Results 31 to 40 of about 19,584 (228)

Candida albicans and Pseudomonas aeruginosa interaction, with focus on the role of eicosanoids

open access: yesFrontiers in Physiology, 2016
Candida albicans is commonly found in mixed infections with Pseudomonas aeruginosa, especially in the lungs of cystic fibrosis patients. Both of these opportunistic pathogens are able to form resistant biofilms and frequently infect immunocompromised ...
Ruan eFourie   +6 more
doaj   +1 more source

Distinct eicosanoid patterns in severe recalcitrant nasal polyposis

open access: yes, 2023
BACKGROUND: Although altered eicosanoid levels are related to disease severity in chronic rhinosinusitis with nasal polyps (CRSwNP), identifying patients prone to recurrent NPs is still difficult.
Jangard, Mattias   +9 more
core   +1 more source

Inhibition of Granuloma Triglyceride Synthesis Imparts Control of Mycobacterium tuberculosis Through Curtailed Inflammatory Responses

open access: yesFrontiers in Immunology, 2021
Lipid metabolism plays a complex and dynamic role in host-pathogen interaction during Mycobacterium tuberculosis infection. While bacterial lipid metabolism is key to the success of the pathogen, the host also offers a lipid rich environment in the form ...
Stanzin Dawa   +13 more
doaj   +1 more source

Eicosanoids and cancer

open access: yesClinics, 2018
Eicosanoids are 20-carbon bioactive lipids derived from the metabolism of polyunsaturated fatty acids, which can modulate various biological processes including cell proliferation, adhesion and migration, angiogenesis, vascular permeability and inflammatory responses.
Gomes, Renata Nascimento   +2 more
openaire   +5 more sources

The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells

open access: yes, 2008
Activated mast cells are a major source of the eicosanoids PGD(2) and leukotriene C(4) (LTC(4)), which contribute to allergic responses. These eicosanoids are produced following the ERK1/2-dependent activation of cytosolic phospholipase A(2), thus ...
Hye Sun Kuehn   +11 more
core   +1 more source

Total synthesis of the endogenous inflammation resolving lipid resolvin D2 using a common lynchpin

open access: yesBeilstein Journal of Organic Chemistry, 2013
The total synthesis of the endogenous inflammation resolving eicosanoid resolvin D2 (1) is described. The key steps involved a Wittig reaction between aldehyde 5 and the ylide derived from phosphonium salt 6 to give enyne 17 and condensation of the same ...
John Li   +3 more
doaj   +1 more source

the-enzymes-of-the-human-eicosanoid-pathway.pdf

open access: yes, 2018
Although there are a number of excellent reviews on various aspects of eicosanoid metabolism, this review was written to not only bring the subject up to date, but to do so in a highly comprehensive manner.
Roger Biringer (8324466)
core   +1 more source

Prostanoid Metabolites as Biomarkers in Human Disease

open access: yesMetabolites, 2022
Prostaglandins (PGD2, PGE2, PGF2α), prostacyclin (PGI2), and thromboxane A2 (TXA2) together form the prostanoid family of lipid mediators. As autacoids, these five primary prostanoids propagate intercellular signals and are involved in many physiological
Helena Idborg, Sven-Christian Pawelzik
doaj   +1 more source

Outlining eicosanoid biosynthesis in the crustacean Daphnia [PDF]

open access: yes, 2008
Background: Eicosanoids are biologically active, oxygenated metabolites of three C20 polyunsaturated fatty acids. They act as signalling molecules within the autocrine or paracrine system in both vertebrates and invertebrates mainly functioning as ...
Callaghan Amanda   +14 more
core   +1 more source

Antithetic relationship of dietary arachidonic acid and eicosapentaenoic acid on eicosanoid production in vivo

open access: yesJournal of Lipid Research, 1994
Eicosanoids are oxidative derivatives of arachidonic acid. When produced in excessive amounts, many are proinflammatory and/or prothrombotic agents. N-3 polyunsaturated fatty acids (PUFA) have been used to attenuate tissue arachidonic acid (AA, 20:4 n-6)
B Li, C Birdwell, J Whelan
doaj   +1 more source

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