Results 71 to 80 of about 19,584 (228)
The FEBS Journal, EarlyView.Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo +4 more
wiley +1 more source
athar71/Eicosanoids_HFpEF: Version 1 for HFpEF Eicosanoid Paper
, 2023 First Release for HFpEF Eicosanoid Project <p>This includes the functions for reading and preprocessing the metabolites data as well as the mediation analyses code.</p ...
Athar Roshandelpoor
core +1 more source
Seasonal changes in eicosanoid metabolism in the brown bear [PDF]
, 2018 International audiencePolyunsaturated fatty acids (PUFAs) exert several important functions across organ systems. During winter, hibernators divert PUFAs from oxidation, retaining them in their tissues and membranes, to ensure proper body functions at ...
Swenson, Jon +15 more
core +2 more sources
Coupling of COX-1 to mPGES1 for prostaglandin E2 biosynthesis in the murine mammary gland
Journal of Lipid Research, 2005 The mammary gland, like most tissues, produces measurable amounts of prostaglandin E2 (PGE2), a metabolite of arachidonic acid produced by sequential actions of two cyclooxygenases (COX-1 and COX-2) and three terminal PGE synthases: microsomal ...
Subhashini Chandrasekharan +5 more
doaj +1 more source
The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
s – Novel Therapeutic Targets of Eicosanoid Signalling
, 2014 MicroRNAs (miRNAs) have emerged as important regulators in human physiological and pathological processes. We summarize the current knowledge about the role of miRNA involved in the control of inflammatory responses with a special focus on eicosanoid ...
Suess, Beatrix +5 more
core +1 more source
Journal of Lipid Research, 2016 Leukotrienes (LTs) play major roles in lung immune responses, and LTD4 is the most potent agonist for cysteinyl LT1, leading to bronchoconstriction and tissue remodeling. Here, we studied LT crosstalk between myeloid cells and pulmonary epithelial cells.
Ana Lukic +6 more
doaj +1 more source
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims Gestational diabetes mellitus (GDM) poses major health risks for mothers and infants. Evidence on the association between dietary protein intake and GDM risk remains inconsistent. This study investigated dietary protein quantity and quality in relation to GDM.
Marzieh Zare +5 more
wiley +1 more source
Journal of Fish Biology, EarlyView.Abstract High‐latitude ecosystems are simultaneously warming and acidifying under ongoing climate change. Arctic cod (Boreogadus saida) are a key species in the Arctic Ocean and have demonstrated sensitivity to ocean warming and acidification as adults and embryos, but their larval sensitivity to the combined stressors is unknown. In a laboratory multi‐
Emily Slesinger +6 more
wiley +1 more source
, 1992 Eicosanoids, in particular prostaglandin E2 (PGE2), are potent inhibitors of a number of immune responses, including lymphocyte proliferation. We have previously shown that fatty acids, especially polyunsaturated fatty acids (PUFA), inhibit mitogen ...
Calder, P.C. +2 more
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