Results 81 to 90 of about 21,372 (200)
Seasonal changes in eicosanoid metabolism in the brown bear [PDF]
, 2018 International audiencePolyunsaturated fatty acids (PUFAs) exert several important functions across organ systems. During winter, hibernators divert PUFAs from oxidation, retaining them in their tissues and membranes, to ensure proper body functions at ...
Swenson, Jon +15 more
core +2 more sources
The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
athar71/Eicosanoids_HFpEF: Version 1 for HFpEF Eicosanoid Paper
, 2023 First Release for HFpEF Eicosanoid Project <p>This includes the functions for reading and preprocessing the metabolites data as well as the mediation analyses code.</p ...
Athar Roshandelpoor
core +1 more source
Journal of Fish Biology, EarlyView.Abstract High‐latitude ecosystems are simultaneously warming and acidifying under ongoing climate change. Arctic cod (Boreogadus saida) are a key species in the Arctic Ocean and have demonstrated sensitivity to ocean warming and acidification as adults and embryos, but their larval sensitivity to the combined stressors is unknown. In a laboratory multi‐
Emily Slesinger +6 more
wiley +1 more source
METHOD FOR MODULATING EICOSANOID MEDIATED IMMUNE RESPONSES IN ARTHROPODS [PDF]
, 2000 The invention is directed to compositions which alter the health of invertebrate organisms by affecting eicosanoid mediated immune responses, and methods of using the compositions.
Stanley, David W.
core
The Group IVA Cytosolic Phospholipase A2/C1P Interaction and Its Role in Eicosanoid Synthesis and Inflammation [PDF]
, 2014 In the presented study, we demonstrate that the interaction of group IVA cytosolic phospholipase A2 and ceramide-1-phosphate is crucial for production of eicosanoid synthesis in inflammation.
Mietla, Jennifer A.
core +1 more source
Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer
Frontiers in Cell and Developmental Biology, 2016 Colorectal cancer is the third most common cancer worldwide and is associated with significant morbidity and mortality. Current pharmacotherapy options include cytotoxic chemotherapy, anti-VEGF and anti-EGFR targeting drugs, but these are limited by ...
Lorraine Burke +7 more
doaj +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
EicosaCell: An Imaging-Based Assay to Identify Spatiotemporal Eicosanoid Synthesis
, 2017 Acesso aberto em 20/04/2020 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774667/Eicosanoids are bioactive lipids derived from enzymatic metabolism of arachidonic acid via the cyclooxygenase (COX) and lipoxygenase (LOX) pathways. These lipids are newly
Christianne Bandeira-Melo +9 more
core +1 more source
Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson +6 more
wiley +1 more source