Results 91 to 100 of about 19,584 (228)
Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, EarlyView.
Jaime Bernaola +14 more
wiley +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Lipidomic analysis of eicosanoid dynamics in inflammation and disease [PDF]
Eicosanoids begin as a single poly-unsaturated fatty acid, arachidonic acid. Yet from this simple origin, hundreds of bioactive signaling molecules can be created, often within minutes of receiving an initiation signal.
Buczynski, Matthew Wallace
core
EicosaCell: An Imaging-Based Assay to Identify Spatiotemporal Eicosanoid Synthesis
Acesso aberto em 20/04/2020 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774667/Eicosanoids are bioactive lipids derived from enzymatic metabolism of arachidonic acid via the cyclooxygenase (COX) and lipoxygenase (LOX) pathways. These lipids are newly
Christianne Bandeira-Melo +9 more
core +1 more source
The mediterranean diet (MD) reduced the risk of colorectal cancer (CRC), and olive oil, the primary source of fat in the MD, has also been found to have a protective effect. However, animals fed with oleic acid present a high number of intestinal tumours,
C. E. Storniolo, J. J. Moreno
doaj +1 more source
The role of neutrophils in the pathophysiology of inflammatory bowel diseases
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens +8 more
wiley +1 more source
Mitochondrial control of ciliary gene expression and structure in striatal neurons
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen +5 more
wiley +1 more source
Irradiation of Protoporphyric Mice Induces Down-Regulation of Epidermal Eicosanoid Metabolism
This study investigated the effect of radiation on clinical and histologic changes, and on cutaneous eicosanoid metabolism, in Skh:HR-1 hairless albino mice rendered protoporphyric by the administration of collidine. At 0.1–18h after exposure to 12 kJ/m2
He, Dan, Lim, Henry W
core +1 more source
Delta-6 desaturase (D6D) catalyzes the first step in the synthesis of highly unsaturated fatty acids (HUFA) such as arachidonic (AA), docosapentaenoic (DPAn-6), and docosahexaenoic (DHA) acids, as well as the last desaturation of DPAn-6 and DHA.
Chad K. Stroud +11 more
doaj +1 more source

