Results 101 to 110 of about 34,112 (234)
A pilot study comparing the metabolic profiles of elite-level athletes from different sporting disciplines [PDF]
, 2018 Background: The outstanding performance of an elite athlete might be associated with changes in their blood metabolic profile. The aims of this study were to compare the blood metabolic profiles between moderate- and high-power and endurance elite ...
A Boldyrev +51 more
core +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
On the cellular metabolism of the click chemistry probe 19-alkyne arachidonic acid[S]
Journal of Lipid Research, 2016 Alkyne and azide analogs of natural compounds that can be coupled to sensitive tags by click chemistry are powerful tools to study biological processes. Arachidonic acid (AA) is a FA precursor to biologically active compounds.
Philippe Pierre Robichaud +6 more
doaj +1 more source
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT The pharmacokinetics and pharmacodynamics of betamethasone following intra‐articular administration to horses have been described; however, studies characterizing intramuscular administration are lacking. Twenty‐four horses received an intramuscular dose of 12 mg betamethasone sodium phosphate/betamethasone acetate.
Juliana Sullivan +4 more
wiley +1 more source
Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, EarlyView.
Jaime Bernaola +14 more
wiley +1 more source
Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson +6 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju +13 more
wiley +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Periodontology 2000, EarlyView.Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Journal of Lipid Research, 2009 To investigate the mechanisms underlying 15(S)-HETE-induced angiogenesis, we have studied the role of the small GTPase, Rac1. We find that 15(S)-HETE activated Rac1 in human retinal microvascular endothelial cells (HRMVEC) in a time-dependent manner ...
Tieqiang Zhao +8 more
doaj +1 more source
The role of neutrophils in the pathophysiology of inflammatory bowel diseases
Periodontology 2000, EarlyView.Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens +8 more
wiley +1 more source