Results 101 to 110 of about 21,935 (239)

Bradykinin-stimulated eicosanoid synthesis and secretion by rabbit ileal components

, 1987
The eicosanoid profiles, sites of production, and response to bradykinin stimulation were determined in rabbit ileum and its various components by radioimmunoassay of various prostanoids and 5-lipoxygenase products in the incubation media.
L. D. Lawson, D. W. Powell
core   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

s – Novel Therapeutic Targets of Eicosanoid Signalling

, 2014
MicroRNAs (miRNAs) have emerged as important regulators in human physiological and pathological processes. We summarize the current knowledge about the role of miRNA involved in the control of inflammatory responses with a special focus on eicosanoid ...
Suess, Beatrix, Dieter Steinhilber, Ochs, Meike J., Meike J. Ochs, Beatrix Suess, Steinhilber, Dieter   +5 more
core   +1 more source

A novel role for activating transcription factor-2 in 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis*

Journal of Lipid Research, 2009
To investigate the mechanisms underlying 15(S)-HETE-induced angiogenesis, we have studied the role of the small GTPase, Rac1. We find that 15(S)-HETE activated Rac1 in human retinal microvascular endothelial cells (HRMVEC) in a time-dependent manner ...
Tieqiang Zhao, Dong Wang, Sergey Y. Cheranov, Manjula Karpurapu, Koteswara R. Chava, Venkatesh Kundumani-Sridharan, Dianna A. Johnson, John S. Penn, Gadiparthi N. Rao   +8 more
doaj   +1 more source

Association between dietary fatty acids and all‐cause mortality in patients with cirrhosis: A cohort study

Experimental Physiology, EarlyView.
Abstract Liver cirrhosis imposes a substantial global burden, with complications driving high mortality. Diet is pivotal in managing liver disease progression and cirrhosis‐related death. This study investigated associations between total fat intake, specific dietary fatty acid subclasses and all‐cause mortality in cirrhotic patients.
Ali Jafari, Ghazaleh Mahdavi‐Mazdeh, Behnaz Narimani, Helia Mardani, Azita Hekmatdoost, Fereshteh Pashayee‐Khamene, Sara Karimi, Saleheh Ahmadzadeh, Mehdi Saberifiroozi, Behzad Hatami, Zahra Yari   +10 more
wiley   +1 more source

Virus-Transformed Macrophage-Like Cell Line as Tool for Eicosanoid Research

, 1989
The ability of a virus-transformed murine macrophage like cell line HA 38 to produce different eicosanoid metabolites was examined. HA 38 cells release similar amounts of prostaglandins and leukotrienes as did murine peritoneal macrophages in response to
K Wessel, V Kaever, K Resch, W Ostertag, D Bitter-Suermann   +4 more
core   +1 more source

Changes in eicosanoid and tumour necrosis factor-α production by rat peritoneal macrophages during carrageenin-induced peritonitis [PDF]

, 1994
Changes and correlations in cytokine and eicosanoid production by blood monocytes, non-purified and purified peritoneal cells during a carrageenin-induced peritonitis were investigated for a period of ten days.
Zijlstra, F.J. (Freek), F. J. Zijlstra, J. H. P. Wilson, C. J. A. M. Tak, Dijk, A.P.J. (Arie) van, A. P. M. van Dijk, Verdoold, A. (A.), W. M. Pruimboom, Wilson, J.H.P. (Paul), Tak, C.J.A.M. (Corné), Batenburg, M. (M.) van, Pruimboom, W.M. (Wanda), A. Verdoold, M. van Batenburg   +13 more
core   +3 more sources

Synopsis: Special Issue on “Disruption of signaling homeostasis induced crosstalk in the carcinogenesis paradigm Epistemology of the origin of cancer”

4 open, 2019
It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring

Experimental Physiology, EarlyView.
Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas, Cristián A. Amador, Susana Contreras‐Duarte   +2 more
wiley   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source