Results 81 to 90 of about 5,706 (150)

Single‐cell sequencing reveals a regulatory role of WT1 in mast cell proliferation in endometrial polyps

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
We used single‐cell and bulk RNA sequencing to analyze ectopic endometrial polyps (EPs) and adjacent eutopic endometrial tissues (EUs), identifying alterations in cell composition and transcriptional dynamics. Notably, mast cells showed increased activation with distinct transcriptional changes.
Yu Lin, Yiwen Qi, Yutong Yao, Huan Tong, Lan Chen, Weizhou Song, Guojing Li, Hong Xu, Xiaoying He   +8 more
wiley   +1 more source

The roles of lipids in SARS-CoV-2 viral replication and the host immune response

Journal of Lipid Research, 2021
The significant morbidity and mortality associated with severe acute respiratory syndrome coronavirus 2 infection has underscored the need for novel antiviral strategies. Lipids play essential roles in the viral life cycle.
Katherine N. Theken, Soon Yew Tang, Shaon Sengupta, Garret A. FitzGerald   +3 more
doaj  

A Case Study of a Female Infant With Primary Hypertrophic Osteoarthropathy Demonstrates That Early Initiation of Celecoxib Slows but Does Not Prevent Symptom Progression

American Journal of Medical Genetics Part A, Volume 197, Issue 5, May 2025.
ABSTRACT Primary Hypertrophic Osteoarthropathy (PHOAR1) is characterized by autosomal recessive loss of function variants in 15‐hydroxyprostaglandin dehydrogenase (HPGD) leading to digital clubbing, periostosis, pachydermia, and severe hyperhidrosis. HPGD catalyzes the first step of prostaglandin E2 (PGE2) degradation.
Kara Zehr, Morgan Buckley, Joshua W. Owens, Tomas Vanagunas, Patricia Vega Fernandez, Robert J. Hopkin, Amelle Shillington   +6 more
wiley   +1 more source

Role of Polyunsaturated Fatty Acids (PUFAs) and Eicosanoids on Dry Eye Symptoms and Signs

Biomolecules
Polyunsaturated fatty acids (PUFAs) generate pro- and anti-inflammatory eicosanoids via three different metabolic pathways. This study profiled tear PUFAs and their metabolites and examined the relationships with dry eye (DE) and meibomian gland ...
Simran Mangwani-Mordani, Amanda Prislovsky, Daniel Stephenson, Charles E. Chalfant, Anat Galor, Nawajes Mandal   +5 more
doaj   +1 more source

Maternal IgE Influence on Fetal and Infant Health

Immunological Reviews, Volume 331, Issue 1, May 2025.
ABSTRACT Immunoglobulin E (IgE) is the most recently discovered and evolved mammalian antibody type, best known for interacting with mast cells (MCs) as immune effectors. IgE‐mediated antigen sensing by MC provides protection from parasites, venomous animals, bacteria, and other insults to barrier tissues exposed to the environment.
Jozef Balla, Abhay P. S. Rathore, Ashley L. St. John   +2 more
wiley   +1 more source

Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster

Journal of Lipid Research
: Eicosanoids are a class of molecules derived from C20 polyunsaturated fatty acids (PUFAs) that play a vital role in mammalian and insect biological systems, including development, reproduction, and immunity.
Pakeeza Azizpor, Ogadinma K. Okakpu, Sophia C. Parks, Diego Chavez, Fayez Eyabi, Stephanie Martinez-Beltran, Susan Nguyen, Adler R. Dillman   +7 more
doaj  

Effect of cholera toxin on the production of eicosanoids by rat jejunum [PDF]

, 1987
Giuseppina Autore, Francesco Capasso, Giulia Di Carlo, Nicola Mascolo   +3 more
openalex   +1 more source

The eicosanoids in biology and medicine

, 1984
Aaron J. Marcus
openalex   +1 more source

Eicosanoids in health and in disease: An appraisal [PDF]

, 1985
A.J. Higgins
openalex   +1 more source

Editorial: Eicosanoids in Cancer

Frontiers in Pharmacology, 2021
Nune Markosyan, Emer M. Smyth, Paola Patrignani, Emanuela Ricciotti   +3 more
doaj   +1 more source