Results 81 to 90 of about 24,894 (189)
Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu +4 more
wiley +1 more source
In the present study the human monoblast cell line U937 has been used as a model to study the function of human mononuclear phagocytes in asthma. The kinetics of the production of eicosanoids and cytokines, which are thought to play a role in the ...
Ingrid M. Garrelds +5 more
doaj +1 more source
The aim of this study was to investigate the effects of sodium humate (HNa), applied to feed or drinking water as a partial substitution for pharmacological doses of ZnO, on clinical, biochemical and haematological indicators of health status, oxidative ...
M. Trckova +4 more
doaj +1 more source
Integrative analysis of plasma miRNA data (GSE235203) and BM‐MSC transcriptomic data (GSE110359), combined with database‐derived VE/tocopherol target mapping, prioritized SOD1, GCLC, PTGS1, PTGS2, and KDR. Single‐cell localization, CellChat analysis, structural simulation, NHANES contextualization, and GSE286204 supported hypothesis‐generating links to
Ying Ma +8 more
wiley +1 more source
Cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) exhibit potent cardiovascular protective effects in preclinical models, and promoting the effects of EETs has emerged as a potential therapeutic strategy for coronary artery disease (CAD ...
Akinyemi Oni-Orisan +12 more
doaj +1 more source
ABSTRACT Background and Aims Atherosclerosis is a lipid‐induced chronic inflammatory cardiovascular disorder denoted by the infiltration of immune cells and the agglomeration of lipids in the intima, the innermost layer, of the arteries of large and medium sizes.
Ramin Lotfi +4 more
wiley +1 more source
Role of omega-3 unsaturated acids in prevention and treatment of different diseases (part 1)
Currently, one of the most discussed issue in medicine is importance of omega-3 fatty acids for human body. There are several types of omega fatty acids: omega-9, omega-6 and omega-3 polyunsaturated lipids.
E. Yu. Plotnikova +2 more
doaj
In cardiac cells, Plin5/AMPK regulate lipid homeostasis; excess CD36‐mediated uptake drives lipotoxicity, mitochondrial dysfunction, and CVDs (e.g., heart failure). Biomarkers (ApoB/ApoA‐1) and therapies (SGLT2 inhibitors) target this cascade. ABSTRACT Cardiac lipid metabolism is fundamental to myocardial energy homeostasis, with fatty acid oxidation ...
Peiyun Xie +3 more
wiley +1 more source
ABSTRACT Background Skeletal muscle atrophy in amyotrophic lateral sclerosis (ALS) drives loss of muscle strength, function and quality of life in ALS patients. The endocannabinoid system (ECS) regulates muscle homeostasis via regenerative and metabolic processes, and although ECS alterations have been reported in ALS neural tissues, ECS remodelling ...
Sebastiaan Dalle +7 more
wiley +1 more source
Eicosanoids mediate insect immune responses and synthesized by the catalytic activity of phospholipase A2 (PLA2). A uniquely encoded secretory PLA2 (sPLA2) is associated with immune responses of a lepidopteran insect, Spodoptera exigua.
Mohammad Vatanparast +3 more
doaj +1 more source

