Results 1 to 10 of about 4,987,765 (222)
The omega-3 fatty acid eicosapentaenoic acid is required for normal alcohol response behaviors in C. elegans. [PDF]
PLoS ONE, 2014 Alcohol addiction is a widespread societal problem, for which there are few treatments. There are significant genetic and environmental influences on abuse liability, and understanding these factors will be important for the identification of susceptible
Richard C Raabe +3 more
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Journal of Internal Medicine, 2022 The cardiovascular benefit from n‐3 polyunsaturated fatty acids (PUFAs) after acute myocardial infarction (AMI) is controversial, and the importance of serum eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) concentrations for clinical events is
P. Myhre +10 more
semanticscholar +1 more source
Molecular dynamic of omega-3 compounds as an anti-obesity agent into GPR-120 receptor [PDF]
Pharmacia, 2023 Obesity is a cause of comorbid diseases such as type 2 diabetes mellitus, dyslipidemia, hypertension which is based on low-level chronic inflammation. The GPR-120 receptor plays a role in insulin sensitization which is related to diabetes mellitus which ...
Ida Musfiroh +4 more
doaj +3 more sources
Emerging Mechanisms of Cardiovascular Protection for the Omega-3 Fatty Acid Eicosapentaenoic Acid
Arteriosclerosis, Thrombosis and Vascular Biology, 2020 Patients with well-controlled LDL (low-density lipoprotein) levels still have residual cardiovascular risk associated with elevated triglycerides. Epidemiological studies have shown that elevated fasting triglyceride levels associate independently with ...
R. Mason, P. Libby, Deepak L. Bhatt
semanticscholar +1 more source
Arab Journal of Basic and Applied Sciences, 2023 Eicosapentaenoic acid and docosahexaenoic acid are two types of omega-3 fatty acids that provide numerous health benefits. It is thus important to gain the recommended daily intake of eicosapentaenoic acid and docosahexaenoic acid and compensate for ...
Hawra Abdulhussain +7 more
doaj +1 more source
British Journal of Pharmacology, 2020 Hypertension is often characterised by impaired vasodilation involving dysfunction of multiple vasodilatory mechanisms. ω‐3 polyunsaturated fatty acids (PUFAs), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) can reduce blood pressure and ...
Cristiana‐Ioana Bercea +3 more
semanticscholar +1 more source
Eicosapentaenoic acid attenuates renal lipotoxicity by restoring autophagic flux
Autophagy, 2020 Recently, we identified a novel mechanism of lipotoxicity in the kidney proximal tubular cells (PTECs); lipid overload stimulates macroautophagy/autophagy for the renovation of plasma and organelle membranes to maintain the integrity of the PTECs ...
Takeshi Yamamoto +18 more
semanticscholar +1 more source
Definitions, 2020 An essential, polyunsaturated, 20-carbon omega-3 fatty acid with anti-inflammatory and potential antineoplastic and chemopreventive activities. Eicosapentaenoic acid (EPA) may activate caspase 3, resulting in apoptosis in susceptible tumor cell ...
semanticscholar +1 more source
Frontiers in Immunology, 2021 The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros +6 more
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Eicosapentaenoic Acid Monoacylglyceride
Definitions, 2020 An eicosapentaenoic acid derivative with potential antineoplastic activities. Upon oral administration, eicosapentaenoic acid monoacylglyceride (MAG-EPA) may inhibit epidermal growth factor receptor (EGFR), vascular endothelial growth factor receptor ...
semanticscholar +1 more source