Results 91 to 100 of about 77,099 (297)

Dietary Intake of Natural Sources of Docosahexaenoic Acid and Folate in Pregnant Women of Three European Cohorts [PDF]

, 2008
Background: Folic acid plays a fundamental role in cell division and differentiation. Docosahexaenoic acid (DHA) has been associated with infantile neurological and cognitive development.
Campoy, C., Decsi, Tamás, Dolz, V., Franke, Corinna, Koletzko, Berthold, Trak-Fellermeier, M., Verwied-Jorky, Sabine   +6 more
core   +1 more source

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, EarlyView.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source

Blood serum from individuals with Alzheimer’s disease alters microglial phagocytosis in vitro

Neural Regeneration Research
In Alzheimer’s disease, microglial phagocytosis is engaged in the pathogenesis as it clears abnormal protein accumulations, debris, and apoptotic cells in the early stages of Alzheimer’s disease, but fuels neuroinflammation and accelerates disease ...
Barbara Altendorfer, Rodolphe Poupardin, Sophie Lefèvre-Arbogast, Claudine Manach, Dorrain Y. Low, Mireia Urpi-Sarda, Cristina Andres-Lacueva, Raúl González-Domínguez, Thomas K. Felder, Julia Tevini, Marco Zattoni, Andreas Koller, Reinhold Schmidt, Paul J. Lucassen, Silvie R. Ruigrok, Chiara de Lucia, Andrea Du Preez, Catherine Helmer, Jeanne Neuffer, Cécile Proust-Lima, Aniko Korosi, Cécilia Samieri, Sandrine Thuret, Ludwig Aigner   +23 more
doaj   +1 more source

Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. [PDF]

, 2016
Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions.
Hammock, Bruce D, Hye Khan, Md Abdul, Imig, John D, Lee, Kin Sing Stephen, Levick, Scott P, Sharma, Amit   +5 more
core   +3 more sources

Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms

British Journal of Pharmacology, EarlyView.
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl, Jakub Morze, Sabina Wallerer, Georg Hoffmann   +3 more
wiley   +1 more source

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Belcher, P.R., Caslake, M.J., Chaudhry, M.A., Day, S., Muriithi, E.W., Wheatley, D.J.   +5 more
core   +1 more source

Body composition and sensory quality of wild and farmed brown-trout (Salmo trutta) and of farmed rainbow-trout (Oncorhynchus mykiss)

Ciência Rural, 2018
: Body composition (total crude protein, lipid, ash, dry matter and moisture) and fatty acid profiles were compared between wild and farmed brown trout and between farmed rainbow trout.
Ana Maria Antão-Geraldes, Sílvia Rafael Hungulo, Etelvina Pereira, Amílcar Teixeira, Alfredo Teixeira, Sandra Rodrigues   +5 more
doaj   +1 more source

Downregulated serum 14, 15-epoxyeicosatrienoic acid is associated with abdominal aortic calcification in patients with primary aldosteronism [PDF]

, 2018
Patients with primary aldosteronism (PA) have increased risk of target-organ damage, among which vascular calcification is an important indicator of cardiovascular mortality.
Gao, Jingwei, He, Wanbing, Huang, Hui, Lin, Ying, Liu, Pinming, Shi, Guangzi, Touyz, Rhian M., Yan, Li, Zhang, Shaoling   +8 more
core   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Standard and Specialized Infant Formulas in Europe: Making, Marketing, and Health Outcomes [PDF]

, 2019
Infant formulas are the only suitable substitute for human milk. The most common infant formulas are standard formulas based on cow's milk. In addition, there are formulas for infants showing signs and symptoms of intolerance and for clinical conditions ...
Corsello G, Dipasquale V, Romano C, Serra G   +3 more
core   +1 more source