Results 81 to 90 of about 35,660 (219)

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

open access: yesObesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye   +6 more
wiley   +1 more source

Eicosapentaenoic acid production by Phaeodactylum tricornutum under different culture condition

open access: yesInternational Journal of Horticultural Science, 2004
Phaeodactylum tricornutum UTEX 640 strain of microalgae was screened under different culture conditions for their capacity to produce eicosapentaenoic acid (EPA) the most abundant polyunsaturated fatty acid (PUFA).
J. Kutasi   +3 more
doaj   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Binding modes of the metabolites docosahexaenoic acid, eicosapentaenoic acid, and eicosapentaenoic acid ethyl ester from Caulerpa racemosa as COX-2 inhibitors revealed via metabolomics and molecular dynamics

open access: yesInformatics in Medicine Unlocked
A total of 116 metabolites of Caulerpa racemosa were identified. However, only three (DHA, EPA, and EPAS) were found to have high anti-inflammatory potential, with Pa scores ranging from 0.764 to 0,827.
Turmidzi Fath   +5 more
doaj   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

open access: yesObesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid   +22 more
wiley   +1 more source

Stearidonic acid improves eicosapentaenoic acid status: studies in humans and cultured hepatocytes

open access: yesFrontiers in Nutrition
BackgroundAhiflower oil from the seeds of Buglossoides arvensis is rich in α-linolenic acid (ALA) and stearidonic acid (SDA). ALA and SDA are potential precursor fatty acids for the endogenous synthesis of eicosapentaenoic acid (EPA) and docosahexaenoic ...
Ulrike Seidel   +9 more
doaj   +1 more source

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje   +3 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Risk of Delayed Post‐polypectomy Bleeding in Patients With Antithrombotic Therapy

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
Antithrombotic therapy is associated with an increased risk of delayed post‐polypectomy bleeding after endoscopic resection of colorectal polyps ≤15 mm. Despite this increased risk, overall bleeding rates remain low in both per‐patient and per‐lesion analyses. ABSTRACT Objectives Recent changes in the perioperative management of antithrombotic therapy (
Rumiko Tsuboi   +18 more
wiley   +1 more source

Minimally processed, human‐grade diet alters canine epigenetic ageing: Results from a pilot study

open access: yesVeterinary Record Open, Volume 13, Issue 2, December 2026.
Abstract Background Diet plays a critical role in promoting wellness and longevity in both humans and canines. Epigenetic ageing clocks have emerged as accurate tools for assessing biological ageing and evaluating dietary and lifestyle interventions in humans and mice.
Aimee Chen   +5 more
wiley   +1 more source

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