Results 81 to 90 of about 77,099 (297)

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

open access: yesPediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang   +6 more
wiley   +1 more source

Comparative Analysis of γ-Cyclodextrin, Perilla Oil, and Their Inclusion Complexes on Liver Injury and Dyslipidemia Associated with Elevated Gastrointestinal 12-Hydroxylated Bile Acid Levels

open access: yesMolecules
Our previous study demonstrated that γ-cyclodextrin (γ-CD)–perilla oil inclusion complexes increase plasma α-linolenic acid and eicosapentaenoic acid levels in healthy rats without adverse effects. The present study examined the effects of perilla oil, γ-
Keisuke Yoshikiyo   +4 more
doaj   +1 more source

Fatty acid profiles in marine and freshwater fish from fish markets in northeastern Poland

open access: yesArchives of Polish Fisheries, 2014
The fatty acid compositions were studied in eight commercially important fish from fish markets: salmon, Salmo salar L.; cod, Gadus morhua L.; common sole, Solea solea (L.); European flounder, Platichthys flesus (L.); catfish, Clarias gariepinus ...
Łuczyńska Joanna   +2 more
doaj   +1 more source

Lipid content and fatty acid dynamics of female muscle, oocytes and larvae of Prochilodus argenteus (Spix & Agassiz, 1829)

open access: yesAquaculture Reports, 2020
This work aimed to determine fatty acid dynamics and lipid composition of female muscle, oocytes, newly hatched larvae (NHL) and first feeding larvae (FFL) of Prochilodus argenteus. Oocytes and NHL had the highest percentages of total lipids.
Edenilce de Fátima Ferreira Martins   +7 more
doaj   +1 more source

FISHing for the Miracle of Eicosapentaenoic Acid

open access: yesNew England Journal of Medicine, 2019
Bhatt et al. report in the Journal the results of the Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial (REDUCE-IT), in which 8179 high-risk patients who had elevated triglyceride levels and had been receiving statin therapy were randomly assigned to receive 2 g of icosapent ethyl twice daily or placebo containing mineral oil.1
Kastelein, John J. P.   +1 more
openaire   +2 more sources

FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]

open access: yes, 2009
Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Heinrich, Joachim   +3 more
core   +1 more source

Transcriptomics Unveil Dsx1 as a Critical Regulator in Sexual Dimorphism of Crustaceans

open access: yesIntegrative Zoology, EarlyView.
Sexually dimorphic traits are involved in reproductive competition and are shaped by sex‐biased gene expression. This study identifies Dsx1 as a key male‐biased gene in Morinoia aosen and demonstrates through RNA interference that its disruption feminizes male‐specific T3 leg structures.
Yan Tong   +8 more
wiley   +1 more source

Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol – Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue

open access: yesCurrent Research in Toxicology
On murine N2a cells, 7-ketocholesterol induced an oxiapotophagic mode of cell death characterized by oxidative stress (reactive oxygen species overproduction on whole cells and at the mitochondrial level; lipid peroxidation), apoptosis induction (caspase-
Aline Yammine   +8 more
doaj   +1 more source

Dry eye disease symptoms and associated risk factors in a Norwegian clinical cohort

open access: yesActa Ophthalmologica, EarlyView.
Abstract Background The relationship between dry eye disease (DED) symptoms and different demographic, clinical and lifestyle factors remains poorly understood. Norway's cold climate and dry indoor air may accelerate tear evaporation, contributing to a very high meibomian gland dysfunction prevalence, as found in multiple studies.
Mazyar Yazdani   +6 more
wiley   +1 more source

The impact of fish oil fatty-acids on post-prandial vascular reactivity. [PDF]

open access: yes, 2014
Progressive loss of vascular reactivity and increased vascular tone with age are being increasingly recognised as significant cardiovascular disease (CVD) risk factors.
Mcmanus, Sean
core  

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