Results 131 to 140 of about 5,052,454 (329)

Eicosapentaenoic acid prevents arterial calcification in klotho mutant mice.

PLoS ONE, 2017
BackgroundThe klotho gene was identified as an "aging-suppressor" gene that accelerates arterial calcification when disrupted. Serum and vascular klotho levels are reduced in patients with chronic kidney disease, and the reduced levels are associated ...
Kazufumi Nakamura, Daiji Miura, Yukihiro Saito, Kei Yunoki, Yasushi Koyama, Minoru Satoh, Megumi Kondo, Kazuhiro Osawa, Omer F Hatipoglu, Toru Miyoshi, Masashi Yoshida, Hiroshi Morita, Hiroshi Ito   +12 more
doaj   +1 more source

Statistical Workflow for Feature Selection in Human Metabolomics Data. [PDF]

, 2019
High-throughput metabolomics investigations, when conducted in large human cohorts, represent a potentially powerful tool for elucidating the biochemical diversity underlying human health and disease.
Antonelli, Joseph, Cheng, Susan, Claggett, Brian L, Demler, Olga V, Deng, Katherine, Henglin, Mir, Hushcha, Pavel V, Jain, Mohit, Kim, Andy, Kim, Nicole, Lagerborg, Kim A, Mora, Samia, Niiranen, Teemu J, Ovsak, Gavin, Pereira, Alexandre C, Rao, Kevin, Tyagi, Octavia, Watrous, Jeramie D   +17 more
core   +2 more sources

Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation

Biological Reviews, EarlyView.
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Victor Murison, Josiane Hérault, Justine Marchand, Lionel Ulmann   +3 more
wiley   +1 more source

Optimization of One-Step In Situ Transesterification Method for Accurate Quantification of EPA in Nannochloropsis gaditana

Applied Sciences, 2016
Microalgae are a valuable source of lipid feedstocks for biodiesel and valuable omega-3 fatty acids. Nannochloropsis gaditana has emerged as a promising producer of eicosapentaenoic acid (EPA) due to its fast growth rate and high EPA content.
Yuting Tang, Yue Zhang, Julian N. Rosenberg, Michael J. Betenbaugh, Fei Wang   +4 more
doaj   +1 more source

Pharmacokinetics of Eicosapentaenoic Acid in Plasma and Red Blood Cells After Multiple Oral Dosing With Icosapent Ethyl in Healthy Subjects

Clinical pharmacology in drug development, 2013
Icosapent ethyl (IPE) is a prescription form of eicosapentaenoic acid (EPA) ethyl ester. This randomized, open‐label study characterized EPA pharmacokinetics.
R. Braeckman, W. Stirtan, Paresh N. Soni
semanticscholar   +1 more source

ACSM5 Regulates Ferroptosis in Hepatocellular Carcinoma by Up‐Regulating POR and Modulating Lipid Metabolism

Cancer Science, EarlyView.
ACSM5 induced ferroptosis in HCC by up‐regulating cytochrome P450 oxidoreductase (POR). The metabolic transformation of linoleic acid to arachidonic acid was also promoted by ACSM5; thereby, the sensitivity to ferroptosis was elevated. ABSTRACT The medium‐chain fatty acyl‐CoA synthetase‐5 (ACSM5) plays a crucial role in the development of some cancers.
Zhengqiang Wu, Xiaofeng Xiong, Mingyi Dong, Linfei Luo, Zixiang Huang, Kedong Xu, Lianwu Zhao, Fenfen Wang, Zhili Wen   +8 more
wiley   +1 more source

Eicosapentaenoic acid (EPA) reduces cardiovascular events: relationship with the EPA/arachidonic acid ratio.

Journal of atherosclerosis and thrombosis, 2013
The clinical efficacy of fish oil and high-purity eicosapentaenoic acid ethyl ester (hp-EPA-E) for treating cardiovascular disease (CVD) has been reported.
H. Ohnishi, Y. Saito
semanticscholar   +1 more source

EICOSAPENTAENOIC ACID IN FAT

The Lancet, 1987
Katan, M.B., van de Bovenkamp, P.
openaire   +7 more sources

Studies relating to Polyunsaturated Fatty Acid (PUFA) Supplementation and Fertility in Cattle [PDF]

, 2007
End of project reportReproductive inefficiency has a significant impact on the economic performance of both dairy and beef herds, particularly in seasonal calving systems. Nutrition plays a fundamental role in reproduction. Furthermore, there is emerging
Childs, Stuart, Diskin, Michael G., Kenny, David A., Sreenan, J.M.   +3 more
core  

n‐3 PUFAs docosahexaenoic acid and eicosapentaenoic acid are effective natural pro‐resolution ingredients for topical skin applications

International Journal of Cosmetic Science, EarlyView.
Skin encounters many challenges that lead to an inflammatory response. Resolution of this inflammation is needed to return the skin to a healthy state. A review of the role of topical n‐3 PUFAs, particularly DHA and EPA, in resolving skin inflammation and promoting skin health is presented.
John Nip, Kevin Hermanson, Jian‐ming Lee   +2 more
wiley   +1 more source