British Journal of Pharmacology, 2020 Hypertension is often characterised by impaired vasodilation involving dysfunction of multiple vasodilatory mechanisms. ω‐3 polyunsaturated fatty acids (PUFAs), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) can reduce blood pressure and ...
Cristiana‐Ioana Bercea +3 more
openalex +2 more sources
The omega-3 fatty acid eicosapentaenoic acid is required for normal alcohol response behaviors in C. elegans. [PDF]
PLoS ONE, 2014 Alcohol addiction is a widespread societal problem, for which there are few treatments. There are significant genetic and environmental influences on abuse liability, and understanding these factors will be important for the identification of susceptible
Richard C Raabe +3 more
doaj +2 more sources
Stearidonic acid improves eicosapentaenoic acid status: studies in humans and cultured hepatocytes. [PDF]
Front NutrBackgroundAhiflower oil from the seeds of Buglossoides arvensis is rich in α-linolenic acid (ALA) and stearidonic acid (SDA). ALA and SDA are potential precursor fatty acids for the endogenous synthesis of eicosapentaenoic acid (EPA) and docosahexaenoic ...
Seidel U +9 more
europepmc +2 more sources
Ala54Thr Fatty Acid-Binding Protein 2 (FABP2) Polymorphism in Recurrent Depression: Associations with Fatty Acid Concentrations and Waist Circumference [PDF]
, 2013 BACKGROUND: Fatty acid (FA)-alterations may mediate the mutual association between Major Depressive Disorder (MDD) and cardiovascular disease (CVD). However, etiology of observed FA-alterations in MDD and CVD remains largely unclear.
Assies, Johanna +7 more
core +20 more sources
The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. [PDF]
Front NutrChoi GY, Calder PC.
europepmc +2 more sources
Molecular dynamic of omega-3 compounds as an anti-obesity agent into GPR-120 receptor [PDF]
Pharmacia, 2023 Obesity is a cause of comorbid diseases such as type 2 diabetes mellitus, dyslipidemia, hypertension which is based on low-level chronic inflammation. The GPR-120 receptor plays a role in insulin sensitization which is related to diabetes mellitus which ...
Ida Musfiroh +4 more
doaj +3 more sources
Emerging Mechanisms of Cardiovascular Protection for the Omega-3 Fatty Acid Eicosapentaenoic Acid
Arteriosclerosis, Thrombosis and Vascular Biology, 2020 Patients with well-controlled LDL (low-density lipoprotein) levels still have residual cardiovascular risk associated with elevated triglycerides. Epidemiological studies have shown that elevated fasting triglyceride levels associate independently with ...
R. Mason, P. Libby, Deepak L. Bhatt
semanticscholar +1 more source
Arab Journal of Basic and Applied Sciences, 2023 Eicosapentaenoic acid and docosahexaenoic acid are two types of omega-3 fatty acids that provide numerous health benefits. It is thus important to gain the recommended daily intake of eicosapentaenoic acid and docosahexaenoic acid and compensate for ...
Hawra Abdulhussain +7 more
doaj +1 more source
Eicosapentaenoic acid attenuates renal lipotoxicity by restoring autophagic flux
Autophagy, 2020 Recently, we identified a novel mechanism of lipotoxicity in the kidney proximal tubular cells (PTECs); lipid overload stimulates macroautophagy/autophagy for the renovation of plasma and organelle membranes to maintain the integrity of the PTECs ...
Takeshi Yamamoto +18 more
semanticscholar +1 more source