Results 41 to 50 of about 6,003 (259)

Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina [PDF]

open access: yes, 2015
Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Calvete, Juan J.   +3 more
core   +12 more sources

ELAPID SNAKE BITE

open access: yesBritish Journal of Anaesthesia, 1987
Four patients were admitted with respiratory muscle paralysis following an elapid snake bite. Two were treated with antivenine, repeated doses of neostigmine and artificial ventilation; the other two with artificial ventilation only. There was no clinically significant difference in recovery.
D K, Pawar, H, Singh
openaire   +2 more sources

NMR solution structure of a chymotrypsin inhibitor from the Taiwan cobra Naja naja atra [PDF]

open access: yes, 2013
The Taiwan cobra (Naja naja atra) chymotrypsin inhibitor (NACI) consists of 57 amino acids and is related to other Kunitz-type inhibitors such as bovine pancreatic trypsin inhibitor (BPTI) and Bungarus fasciatus fraction IX (BF9), another chymotrypsin ...
Chang, Long-Sen   +3 more
core   +2 more sources

Anticoagulant Activity of Naja nigricollis Venom Is Mediated by Phospholipase A2 Toxins and Inhibited by Varespladib

open access: yesToxins, 2021
Bites from elapid snakes typically result in neurotoxic symptoms in snakebite victims. Neurotoxins are, therefore, often the focus of research relating to understanding the pathogenesis of elapid bites.
Taline D. Kazandjian   +7 more
doaj   +1 more source

A Simple and Novel Strategy for the Production of a Pan-specific Antiserum against Elapid Snakes of Asia. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Snakebite envenomation is a serious medical problem in many tropical developing countries and was considered by WHO as a neglected tropical disease.
Kavi Ratanabanangkoon   +8 more
doaj   +1 more source

Engineered nanoparticles bind elapid snake venom toxins and inhibit venom-induced dermonecrosis

open access: goldPLoS Neglected Tropical Diseases, 2018
Envenomings by snakebites constitute a serious and challenging global health issue. The mainstay in the therapy of snakebite envenomings is the parenteral administration of animal-derived antivenoms. Significantly, antivenoms are only partially effective
Jeffrey O’Brien   +3 more
openalex   +3 more sources

Stabilising the Integrity of Snake Venom mRNA Stored under Tropical Field Conditions Expands Research Horizons. [PDF]

open access: yes, 2016
BACKGROUND Snake venoms contain many proteinaceous toxins that can cause severe pathology and mortality in snakebite victims. Interestingly, mRNA encoding such toxins can be recovered directly from venom, although yields are low and quality is unknown ...
Logan, Rhiannon
core   +1 more source

Macroevolution in axial morphospace: innovations accompanying the transition to marine environments in elapid snakes

open access: yesRoyal Society Open Science, 2022
Sea snakes in the Hydrophis-Microcephalophis clade (Elapidae) show exceptional body shape variation along a continuum from similar forebody and hindbody girths, to dramatically reduced girths of the forebody relative to hindbody. The latter is associated
E. Sherratt   +5 more
semanticscholar   +1 more source

Action mechanism of snake venom l-amino acid oxidase and its double-edged sword effect on cancer treatment: Role of pannexin 1-mediated interleukin-6 expression

open access: yesRedox Biology, 2023
Snake venom l-amino acid oxidases (svLAAOs) have been recognized as promising candidates for anticancer therapeutics. However, multiple aspects of their catalytic mechanism and the overall responses of cancer cells to these redox enzymes remain ambiguous.
Nam V. Truong   +5 more
doaj   +1 more source

Identification of presynaptic neurotoxin complexes in the venoms of three Australian copperheads (Austrelaps spp.) and the efficacy of tiger snake antivenom to prevent or reverse neurotoxicity [PDF]

open access: yes, 2011
The venom of the Australian lowlands copperhead, Austrelaps superbus, produces significant and potentially lethal neurotoxic paralysis in cases of clinical envenomation. However, little is known about the neurotoxic components within this venom or venoms
Marcon, F, Nicholson, GM
core   +1 more source

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