Results 91 to 100 of about 11,707 (151)

Diagnosing contaminations of Echis venom pools [PDF]

For research purposes, snake venom is often pooled to obtain sufficient amounts. However, considerable knowledge is necessary to identify snake species and utmost care is required to keep individually venoms well labeled during handling and venom pools ...
Berg, A.M. (Anna), Adeyi, A. (Akindele), König, S. (Simone), Abiola, J. (Julius), Aiyelaagbe, O. (Olapeju)   +4 more
core   +1 more source

Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform

Frontiers in Pharmacology
Snakebite envenoming is a neglected tropical disease that causes as many as 1.8 million envenomings and 140,000 deaths annually. To address treatment limitations that exist with current antivenoms, the search for small molecule drug-based inhibitors that
Laura-Oana Albulescu, Laura-Oana Albulescu, Adam Westhorpe, Adam Westhorpe, Rachel H. Clare, Rachel H. Clare, Christopher M. Woodley, Nivya James, Jeroen Kool, Neil G. Berry, Paul M. O’Neill, Nicholas R. Casewell, Nicholas R. Casewell   +12 more
doaj   +1 more source

Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling

, 2018
Venoms from snakes are rich sources of highly active proteins with potent affinity towards a variety of enzymes and receptors. Of the many distinct toxicities caused by envenomation, neurotoxicity plays an important role in the paralysis of prey by ...
Casewell, Nicholas R., Jeroen Kool, Janaki Iyer, Niessen, Wilfried M.A., Reka A. Otvos, Visser, Jeroen C., August B. Smit, van Doodewaerd, Bjorn R., Jeroen C. Visser, Kini, R. Manjunatha, Cardoso, Fernanda C., Wilfried M.A. Niessen, Richard J. Lewis, R. Manjunatha Kini, Fernanda C. Cardoso, Kool, Jeroen, Casewell, Nick; id_orcid, Iyer, Janaki, Bjorn R. van Doodewaerd, Ryan J.R. McCleary, Slagboom, Julien, Nicholas R. Casewell, Somsen, Govert W., Otvos, Reka A., Lewis, Richard J., Govert W. Somsen, Niessen, Wilfried M.A.; id_orcid, McCleary, Ryan J.R., Smit, August B., Julien Slagboom   +29 more
core   +1 more source

Nanotechnology-based paper microfluidics for rapid point-of-care detection and differentiation of snake venom types

Biosensors and Bioelectronics: X
Snake envenomation is recognized as a neglected tropical disease, contributing to high mortality rates and causing significant organ damage, particularly to the liver, kidneys, and brain.
Lakshmi Narashimhan Ramana, Nitin Salvi, M.V. Khadilkar, Tarun Kumar Sharma   +3 more
doaj   +1 more source

Standard Quality Characteristics and Efficacy of a New Third-Generation Antivenom Developed in Colombia Covering Micrurus spp. Venoms

Toxins
In Colombia, Micrurus snakebites are classified as severe according to the national clinical care guidelines and must be treated with specific antivenoms.
Santiago Tabares Vélez, Lina María Preciado, Leidy Johana Vargas Muñoz, Carlos Alberto Madrid Bracamonte, Angelica Zuluaga, Jeisson Gómez Robles, Camila Renjifo-Ibañez, Sebastián Estrada-Gómez   +7 more
doaj   +1 more source

Elapid three-finger toxin PCR primers.

, 2016
Elapid three-finger toxin PCR primers.
John P. Dunbar (2825906), Kam-Yin D. Leung (2825900), Paul D. Rowley (144846), Nicholas R. Casewell (360450), Robert A. Harrison (144845), Gareth Whiteley (2825894), Fiona J. Newberry (2825903), Simon C. Wagstaff (144848), Rhiannon A. E. Logan (2825897)   +8 more
core   +1 more source

The genomic origins and evolutionary path to a key innovation in the world's most venomous snakes. [PDF]

Proc Natl Acad Sci U S A
van Thiel J, Dowell NL, Smith CF, Sanchez EE, Carroll SB.   +4 more
europepmc   +1 more source

Effects of Selective African Spitting Cobra Venoms and Their Three-Finger Toxins on the Modulation of Platelet Function and Blood Clotting. [PDF]

Toxins (Basel)
Khatibi M, Almeida JR, Al Juwaiser A, Gilabadi S, Patel K, Vaiyapuri S.   +5 more
europepmc   +1 more source

Bite First, Bleed Later: How Philippine Trimeresurus Pit Viper Venoms Hijack Blood Clotting

The Philippines has a high diversity of venomous snake species, but there is minimal information on their envenomation effects. This is evidenced by the small number of case reports, the poor reporting of envenomation cases, and the absence of specific ...
Daniel Albert E. Castillo, Lorenzo Seneci, Abhinandan Chowdhury, Marilyn G. Rimando, Bryan G. Fry   +4 more
core   +1 more source

Antigenic divergence of cobra short-chain α-neurotoxins: Implications for regional antivenom effectiveness in Southeast Asia. [PDF]

PLoS Negl Trop Dis
Tan CH, Palasuberniam P, Pernee LL, Tan KY.   +3 more
europepmc   +1 more source