Results 91 to 100 of about 2,588 (206)

Parallel in vitro ion channel and in vivo zebrafish assaying of elapid snake venoms following chromatographic separation of toxin components

SLAS Discovery
Snake venoms are complex bioactive mixtures designed to paralyse, kill, or digest prey. These venoms are of pharmacological interest due to their ability to modulate molecular targets such as ion channels and receptors with high specificity and potency ...
Arif Arrahman, Haifeng Xu, Muzaffar A. Khan, Tijmen S. Bos, Julien Slagboom, Guus C. van der Velden, Ulrike Nehrdich, Nicholas R. Casewell, Michael K. Richardson, Christian Tudorache, Fernanda C. Cardoso, Jeroen Kool   +11 more
doaj   +1 more source

A Review and Database of Snake Venom Proteomes

Toxins, 2017
Advances in the last decade combining transcriptomics with established proteomics methods have made possible rapid identification and quantification of protein families in snake venoms.
Theo Tasoulis, Geoffrey K. Isbister
doaj   +1 more source

Challenges of regulating commercial use of marine elapid snakes in the Indo‐Pacific

Conservation Biology, Volume 38, Issue 5, October 2024.
Abstract Marine elapid snakes are a diverse, predominantly Indo‐West Pacific species group. The persistent removal of some species has an unquantified but potentially dire impact on populations. We conducted the first comprehensive review of the trade in marine elapid snakes based on published literature (1974–2022) and trade data from the only species
Mark Auliya, Arne Redsted Rasmussen, Kate L. Sanders, Aaron Savio Lobo   +3 more
wiley   +1 more source

Neutralization of the Principal Toxins from the Venoms of Thai Naja kaouthia and Malaysian Hydrophis schistosus: Insights into Toxin-Specific Neutralization by Two Different Antivenoms

Toxins, 2016
Antivenom neutralization against cobra venoms is generally low in potency, presumably due to poor toxin-specific immunoreactivity. This study aimed to investigate the effectiveness of two elapid antivenoms to neutralize the principal toxins purified from
Kae Yi Tan, Choo Hock Tan, Shin Yee Fung, Nget Hong Tan   +3 more
doaj   +1 more source

Immunoreactivity of eastern small eyed snake (Cryptophis nigrescens) venom towards species‐specific antibodies of five medically important venomous Australian elapids

Australian Veterinary Journal, Volume 102, Issue 9, Page 485-488, September 2024.
The eastern small eyed snake (Cryptophis nigrescens; CN) is an uncommon cause of snakebite in Australia despite the widespread distribution of the snake along the east coast of Australia. Diagnosis of envenomation relies on identification of the snake which is often not possible with animal snakebite cases.
AM Padula
wiley   +1 more source

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders [PDF]

, 2014
Background: Spiders have evolved pharmacologically complex venoms that serve to rapidly subdue prey and deter predators. The major toxic factors in most spider venoms are small, disulfide-rich peptides.
Antunes, A, Darling, A, Fry, BG, Kely, L, King, GF, Pineda, SS, Sollod, BL, Sunagar, K, Undheim, EAB, Wilson, D   +9 more
core   +2 more sources

A Documented Case of Ichthyophagy in the Malayan Krait (Bungarus candidus) and Its Implications for Toxinology

Diversity
Snakebite is a neglected tropical disease, and the high potency of snake venoms has been evolutionary refined for trophic interactions. Hence, understanding the feeding ecology of snakes is a major element needed to meaningfully interpret toxinological ...
Tim Lüddecke
doaj   +1 more source

Are ticks venomous animals? [PDF]

, 2017
[Introduction]: As an ecological adaptation venoms have evolved independently in several species of Metazoa. As haematophagous arthropods ticks are mainly considered as ectoparasites due to directly feeding on the skin of animal hosts. Ticks are of major
Cabezas-Cruz, Alejandro, Valdés, James J.   +1 more
core   +1 more source

Atrase A, a P-III class metalloproteinase purified from cobra venom, exhibits potent anticoagulant activity by inhibiting coagulation pathway and activating the fibrinolytic system

Heliyon
Snake venoms, comprising a complex array of protein-rich components, an important part of which are snake venom metalloproteinases (SVMPs). These SVMPs, which are predominantly isolated from viperid venoms, are integral to the pathology of snakebites ...
Xin-Jie Zhong, Cai-E Wang, Ya-Nan Li, Qi-Yun Zhang, Qian-Yun Sun   +4 more
doaj   +1 more source

Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop [PDF]

, 2011
BackgroundEnvenomation by crotaline snakes (rattlesnake, cottonmouth, copperhead) is a complex, potentially lethal condition affecting thousands of people in the United States each year.
Eric J Lavonas, Anne-Michelle Ruha, William Banner, Vikhyat Bebarta, Jeffrey N Bernstein, Sean P Bush, William P Kerns, William H Richardson, Steven A Seifert, David A Tanen, Steve C Curry, Richard C Dart   +11 more
core   +4 more sources