Results 111 to 120 of about 126,008 (360)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors

, 2021
Niccolò Cantini, Letizia Crocetti, Gabriella Guerrini, Claudia Vergelli, Igor A. Schepetkin, Marco Pallecchi, Gianluca Bartolucci, Mark T. Quinn, Elisabetta Teodori, Maria Paola Giovannoni   +9 more
openalex   +2 more sources

Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation

Equine Veterinary Journal, EarlyView.
Abstract Background African horse sickness (AHS), caused by the vector‐borne African horse sickness virus (AHSV), is endemic to sub‐Saharan Africa and infection results in high mortality in naïve equine populations. Clinical signs include submucosal petechiae and prolonged bleeding post venepuncture indicative of hypocoagulation.
Eva Christina Schliewert, Amelia Goddard, Emma H. Hooijberg   +2 more
wiley   +1 more source

Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea)

Marine Drugs, 2012
A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively.
Zhi-Hong Wen, Tsong-Long Hwang, Yueh-Hsiung Kuo, Chih-Han Chang, Jui-Hsin Su, Cheng-Hung Lee, Chia-Ying Kao, Shih-Yao Kao, Ping-Jyun Sung   +8 more
doaj   +1 more source

Compromised inhibition of human lung lavage cell elastases [PDF]

, 1996
Sue Smith, N. A. Roberts, A. Guz, Teresa D. Tetley   +3 more
openalex   +1 more source

Systemic Effects of Vascular Photobiomodulation on Early Macrophage Recruitment During Skeletal Muscle Repair

Journal of Biophotonics, EarlyView.
Preventive vascular photobiomodulation accelerates macrophage recruitment and enhances pro‐regenerative inflammation after skeletal muscle injury, suggesting its potential to improve tissue repair through timely modulation of the immune response. ABSTRACT Muscle injuries involve a complex inflammatory response in which macrophages are essential for ...
Raquel Lira Ortiz da Silva, Tainá Caroline dos Santos Malavazzi, Aline Souza Silva, Sandra Kalil Bussadori, Anna Carolina Ratto Tempestini Horliana, Fabio Daumas Nunes, Kristianne Porta Santos Fernandes, Maria Fernanda Setubal Destro Rodrigues, Raquel Agnelli Mesquita‐Ferrari   +8 more
wiley   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

DOCK8 deficiency presenting with sclerosing cholangitis, raised immunoglobulin E, and bronchiectasis: A fatal pediatric case report

JPGN Reports, EarlyView.
Abstract Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare autosomal recessive primary immunodeficiency. Patients with DOCK8 deficiency typically present at early age with allergic manifestations, cutaneous and respiratory infections, raised immunoglobulin E, and they have an increased risk of developing malignancies.
Natalia Nedelkopoulou, Kelechi Ugonna, Stephen Hughes, Sanjay Rajwal, Marumbo Mtegha   +4 more
wiley   +1 more source

A rare case of pediatric autoimmune pancreatitis and autoimmune hepatitis in a patient with sickle cell disease

JPGN Reports, EarlyView.
Abstract Concurrent pediatric autoimmune pancreatitis (AIP) and autoimmune hepatitis (AIH) are rarely reported, and no established pediatric‐specific guidelines are available to guide the diagnosis and management of these conditions in children. While AIP and AIH share an underlying autoimmune mechanism of injury, marked by chronic inflammatory changes
Sasha‐Jane Abi‐Aad, Michelle Edward, David Germain, Rene Gomez‐Esquivel, Racha Khalaf   +4 more
wiley   +1 more source

Pediatric intestinal pseudo‐obstruction found in 3‐year‐old male with Rett‐related mutation of methyl‐CpG binding protein 2

JPGN Reports, EarlyView.
Abstract A 3‐year‐old male with chronic abdominal distention, constipation, and severe malnutrition is diagnosed with pediatric intestinal pseudo‐obstruction (PIPO) after extensive evaluation that excluded mechanical, malabsorptive, metabolic, inflammatory, and infectious causes. Aside from speech delay, he has a normal neurologic exam.
Angela Tran, Namrata Patel‐Sanchez
wiley   +1 more source