Results 121 to 130 of about 115,118 (303)

CdrA Interactions within the Pseudomonas aeruginosa Biofilm Matrix Safeguard It from Proteolysis and Promote Cellular Packing

open access: yesmBio, 2018
Biofilms are robust multicellular aggregates of bacteria that are encased in an extracellular matrix. Different bacterial species have been shown to use a range of biopolymers to build their matrices.
Courtney Reichhardt   +4 more
doaj   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell‐Derived Microvesicles Alleviate Bronchopulmonary Dysplasia in Preterm Rats by Inhibiting Neutrophil Extracellular Trap Formation

open access: yesPediatric Discovery, EarlyView.
Excessive neutrophil extracellular trap (NET) extrusion (NETosis) links prenatal inflammation to bronchopulmonary dysplasia (BPD) pathogenesis. Treatment with human umbilical cord mesenchymal stem cell‐derived microvesicles suppresses NET formation, reduces lung injury, and promotes alveolarization in a preterm rat model, offering a promising cell‐free
Yi Lu   +10 more
wiley   +1 more source

Study on Patients with Elevated Levels of FDP Presumably Produced by Ganulocyte Elastase [PDF]

open access: yes, 1995
Granulocyte elastase (GEL)-α\-antitrypsin complex (EAT) levels were determined by enzyme immunoassay in plasmas from twelve patients with disseminated intravascular coagulation (DIC) and eight recipients of living related liver transplantation (LLT), and
奥村, 伸生   +11 more
core  

Emphysema in an 11‐month‐old boy with alpha‐1 antitrypsin deficiency

open access: yesPediatric Investigation, EarlyView.
Pediatric development of emphysema in Alpha‐1 Antitrypsin Deficiency (A1ATD) has been rarely described. In this case report, we document an 11‐month boy with A1ATD phenotype PiZZ with basilar centrilobular emphysema, the earliest such documented case.
Irvin Yi   +3 more
wiley   +1 more source

Dysregulation of Mitochondrial Homeostasis in Cardiovascular Diseases

open access: yesPharmaceuticals
Mitochondria dysfunction plays a central role in the development of vascular diseases as oxidative stress promotes alterations in mitochondrial morphology and function that contribute to disease progression.
Ricky Patil   +4 more
doaj   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

open access: yesPhytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia   +1 more
wiley   +1 more source

Bioactivity Screening of Extracts from Icelandic Seaweeds for Potential Application in Cosmeceuticals

open access: yesPhycology
Seaweed is a great source of biologically active metabolites which could prove interesting in cosmeceutical applications. In this study, seven Icelandic seaweed species (Ascophyllum nodosum, Alaria esculenta, Laminaria hyperborea, Laminaria digitata ...
Sophie Jensen   +2 more
doaj   +1 more source

Neutrophil Elastase-Mediated Degradation of IRS-1 Accelerates Lung Tumor Growth

open access: yesNature Medicine, 2010
Lung cancer is the leading cause of cancer death worldwide. Recent data suggest that tumor-associated inflammatory cells may modify lung tumor growth and invasiveness.
A. Houghton   +15 more
semanticscholar   +1 more source

Fluorination as a Molecular Design Parameter for Programming Peptide Nanocarriers

open access: yesSmall, EarlyView.
Controlled side‐chain fluorination programs the SA, morphology, and biological performance of amphiphilic fluoropeptide–RGD nanocarriers. A narrow fluorination window yields compact non‐amyloid fibrils with high loading capacity, pH‐triggered release, receptor‐specific uptake, low cytotoxicity, and enzymatic degradability.
Maurizio Iannuzzi   +10 more
wiley   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

open access: yesVIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro   +6 more
wiley   +1 more source

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