Results 31 to 40 of about 87,970 (343)
The Role of Neutrophils and Neutrophil Elastase in Pulmonary Arterial Hypertension
Frontiers in Medicine, 2018 Pulmonary arterial hypertension (PAH) is a severe vasculopathy characterized by the presence of fibrotic lesions in the arterial wall and the loss of small distal pulmonary arteries.
Shalina Taylor +4 more
semanticscholar +1 more source
Pteridines, 1998 Aim: The aim of the study was to determine whether orthotopic liver transplantation leads to the activation of macrophages, neutrophils and complement.
Tomasdottir H. +3 more
doaj +1 more source
A Spectrophotometric Method for Determination of Elastase and Serum Elastase Inhibitor.
Experimental Biology and Medicine, 1962 SummaryA spectrophotometric method for determination of elastase and elastase-inhibitory activity has been presented, incorporating Sachar's method of enzymatic digestion of an elastin-orcein substrate with subsequent extraction of the orcein dye from solution with n-butyl alcohol.
S. Chao, John J. Sciarra, G. J. Vosburgh
openaire +3 more sources
Neutrophil Elastase Inhibitors and Chronic Kidney Disease
International Journal on Biological Sciences, 2018 End-stage renal disease (ESRD), the last stage of chronic kidney disease (CKD), is characterized by chronic inflammation and oxidative stress. Neutrophils are the front line cells that mediate an inflammatory response against microorganisms as they can ...
E. Bronze-da-Rocha, A. Santos-Silva
semanticscholar +1 more source
Antioxidant and Antiaging Potential of Salak Fruit Extract (Salacca zalacca (Gaert.)Voss)
Majalah Obat Tradisional, 2023 Natural skin aging is indicated by a loss of skin structure and integrity caused by external factors including UV exposure. This exposure causes oxidative stress on skin cells, initiates aging, and degradation of extracellular matrix (ECM) structure ...
Wahyu Widowati +3 more
doaj +1 more source
Undervalued ubiquitous proteins
4 open, 2019 The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
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The propeptide of Pseudomonas aeruginosa elastase acts an elastase inhibitor.
Journal of Biological Chemistry, 1994 Elastase, an extracellular protease of Pseudomonas aeruginosa, is synthesized as a preproenzyme containing a large amino-terminal propeptide. The propeptide is cleaved within the periplasm to form a noncovalent complex with the elastase moiety. The propeptide-elastase complex was purified from the cell extract of P.
Efrat Kessler, Mary Safrin
openaire +3 more sources
Acta Neuropathologica Communications, 2018 After spinal cord injury (SCI), neutrophil elastase (NE) released at injury site disrupts vascular endothelium integrity and stabilization. Angiopoietins (ANGPTs) are vascular growth factors that play an important role in vascular stabilization.
Hemant Kumar +13 more
semanticscholar +1 more source
Frontiers in Neurology, 2022 BackgroundRabbit elastase-induced aneurysms have widely been used to test various endovascular materials over the past two decades. However, wide-necked aneurysms cannot be stably constructed.ObjectiveThe purpose of the study was to increase the neck ...
Yang Zhang +12 more
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Frontiers in Cardiovascular Medicine, 2022 BackgroundAbdominal aortic aneurysm (AAA), characterized by a continued expansion of the aorta, leads to rupture if not surgically repaired. Mice aid the study of disease progression and its underlying mechanisms since sequential studies of aneurysm ...
Stephanie Morgan +18 more
doaj +1 more source