Results 61 to 70 of about 113,787 (215)

Bioactive Compounds from a Gorgonian Coral <em>Echinomuricea</em> sp. (Plexauridae)

Marine Drugs, 2012
A new labdane-type diterpenoid, echinolabdane A (<strong>1</strong>), and a new sterol, 6-<em>epi</em>-yonarasterol B (<strong>2</strong>), were isolated from a gorgonian coral identified as <em>Echinomuricea</
Jih-Jung Chen, Wei-Hsien Wang, Ping-Jyun Sung, Jan-Jung Li, Tsong-Long Hwang, Mei-Chin Lu, Lee-Shing Fang, Yang-Chang Wu, Hsu-Ming Chung, Pei-Han Hong, Jui-Hsin Su   +10 more
doaj   +1 more source

Staging chronic pancreatitis with exocrine function tests: Are we better? [PDF]

, 2017
Chronic pancreatitis (CP) is an inflammatory disease of the pancreas evolving in progressive fibrotic disruption of the gland with exocrine and endocrine pancreatic insufficiency.
MOLETTA, LUCIA, SPERTI, COSIMO
core   +1 more source

Spontaneous Breathing Through Increased Airway Resistance Augments Elastase-Induced Pulmonary Emphysema

International Journal of COPD, 2020
Dimitrios Toumpanakis,1,2 Eleftheria Mizi,1 Vyronia Vassilakopoulou,1 Maria Dettoraki,1 Athanasia Chatzianastasiou,1 Fotis Perlikos,1 Georgia Giatra,2 Marina Moscholaki,1 Stamatios Theocharis,3 Theodoros Vassilakopoulos1,2 1“Marianthi Simou&rdquo ...
Toumpanakis D, Mizi E, Vassilakopoulou V, Dettoraki M, Chatzianastasiou A, Perlikos F, Giatra G, Moscholaki M, Theocharis S, Vassilakopoulos T   +9 more
doaj  

Structure of protease-cleaved escherichia coliα-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment [PDF]

, 2015
Bacterial -2-macroglobulins have been suggested to function in defence as broad-spectrum inhibitors of host proteases that breach the outer membrane.
Burchmore, R.J.S., Byron, O., Cogdell, R.J., Fyfe, C.D., Grinter, R., Josts, I., Mosbahi, K., Roszak, A.W., Walker, D., Wall, D.M.   +9 more
core   +2 more sources

CdrA Interactions within the Pseudomonas aeruginosa Biofilm Matrix Safeguard It from Proteolysis and Promote Cellular Packing

mBio, 2018
Biofilms are robust multicellular aggregates of bacteria that are encased in an extracellular matrix. Different bacterial species have been shown to use a range of biopolymers to build their matrices.
Courtney Reichhardt, Cynthis Wong, Daniel Passos da Silva, Daniel J. Wozniak, Matthew R. Parsek   +4 more
doaj   +1 more source

Proteinaceous receptors for the import of mitochondrial precursor proteins [PDF]

, 1984
Mild trypsin treatment of isolated Neurospora mitochondria strongly inhibits their ability to bind and import the precursors of several mitochondrial proteins.
Neupert, Walter, Schleyer, Manfred, Zwizinski, Craig   +2 more
core  

Aprotinin reduces cardiac troponin I release and inhibits apoptosis of polymorphonuclear cells during off-pump coronary artery bypass surgery [PDF]

, 2008
Objectives: In addition to blood-sparing effects, aprotinin may have cardioprotective and anti-inflammatory effects during cardiopulmonary bypass-assisted cardiac surgery.
Bert, C., Ceuppens, J., De Buck, F., Delforge, M., Kasran, A., Meyns, B., Sergeant, P., Van Duppen, V., Van Hemelrijck, J., Wouters, Patrick   +9 more
core   +2 more sources

Possible role of the phagocytic proteinases, cathepsin B and elastas, in orthotopic liver transplantation [PDF]

, 1991
Kein ...
Himmelreich, G., Jochum, Marianne, Machleidt, W., Riess, H., Slama, R., Steffen, R.   +5 more
core   +1 more source

Dysregulation of Mitochondrial Homeostasis in Cardiovascular Diseases

Pharmaceuticals
Mitochondria dysfunction plays a central role in the development of vascular diseases as oxidative stress promotes alterations in mitochondrial morphology and function that contribute to disease progression.
Ricky Patil, Hui Wang, Matthew Kazaleh, Gorav Ailawadi, Morgan Salmon   +4 more
doaj   +1 more source

Allosteric modulation of beta1 integrin function induces lung repair in animal model of emphysema. [PDF]

, 2007
Emphysema is a progressive lung disease characterised by loss of lung parenchyma with associated functional changes including decreased tissue elastance. Here we report beta1 integrin is a novel target for tissue repair and regeneration in emphysema.
Chris J. Armit, David J. Harrison, Linda Wilson, Mark Marsden, Rehab J. Al-Jamal, Steven D. Shapiro, Susan McIntyre   +6 more
core   +1 more source