Results 61 to 70 of about 87,970 (343)

Evaluation of Elastase and α1-Proteinase Inhibitor-Elastase Uptake by Polymorphonuclear Leukocytes and Evidence of an Elastase-Specific Receptor [PDF]

Clinical Chemistry and Laboratory Medicine, 1986
Neither resting nor stimulated isolated human polymorphonuclear leukocytes did bind or ingest preformed complexes of alpha 1-proteinase inhibitor and unlabeled/125I-labeled human leukocyte elastase. In contrast, granulocytes bound unlabeled/125I-labeled elastase and the extent of binding was reduced in the presence of respiratory burst stimulators ...
Dwenger, A., Tost, P., Holle, W.
openaire   +3 more sources

Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis

Scientific Reports, 2016
Streptococcus pneumoniae is a leading cause of bacterial pneumonia and is the principal cause of morbidity and mortality worldwide. Previous studies suggested that excessive activation of neutrophils results in the release of neutrophil elastase, which ...
H. Domon, M. Oda, T. Maekawa, K. Nagai, Wataru Takeda, Y. Terao   +5 more
semanticscholar   +1 more source

Biomimetic, Suturable, and Extensible Electrospun Scaffolds for Lower Urinary Tract Surgical Reconstruction

Advanced Healthcare Materials, EarlyView.
Biomimetic, suturable, biodegradable fibrous scaffolds are engineered to mimic the tensile properties of LUT tissue using photocrosslinked 5:5% weight per volume elastin‐like peptide and methacrylated gelatin (5E5G). In vitro, urothelium, smooth muscle, and fibroblast 7 day cytocompatibility is demonstrated.
Renea M. Sturm, Yadi Huo, Felix Yiu, Yimin Gu, Ronak Afshari, Zijian Zhong, Ruby Jimenez, Rebekah Jung, Aljohn Cabuan, Keshav Shukla, Karen Harrison, Judy Su, George E. Aninwene II, Victoria Lee, Mahsa Ghovvati, Kaavian Shariati, Nicholas Jackson, Song Li, Nasim Annabi   +18 more
wiley   +1 more source

Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea)

Marine Drugs, 2012
A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively.
Zhi-Hong Wen, Tsong-Long Hwang, Yueh-Hsiung Kuo, Chih-Han Chang, Jui-Hsin Su, Cheng-Hung Lee, Chia-Ying Kao, Shih-Yao Kao, Ping-Jyun Sung   +8 more
doaj   +1 more source

Anti-Aging Potential of Extracts from Washingtonia filifera Seeds

Plants, 2021
The aim of this study was to test the inhibitory effect of fruit extracts from Washingtonia filifera on skin aging-related enzymes. The pulp extracts did not exert a significant enzyme inhibition while seed extracts from W. filifera exhibit anti-elastase,
Benedetta Era, Sonia Floris, Valeria Sogos, Clara Porcedda, Alessandra Piras, Rosaria Medda, Antonella Fais, Francesca Pintus   +7 more
doaj   +1 more source

Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation

Scientific Reports, 2016
In Duchenne muscular dystrophy, progressive loss of muscle tissue is accompanied by fibrosis, chronic inflammation and reduced muscle regenerative capacity.
N. Arecco, Christopher J. Clarke, Fiona K. Jones, Deborah M. Simpson, David Mason, R. Beynon, A. Pisconti   +6 more
semanticscholar   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Correlation of PMN elastase and PMN elastase-to-neutrophil ratio with disease activity in patients with myositis

Journal of Translational Medicine, 2019
Background Polymorphonuclear (PMN) elastase plays an important role in a variety of inflammatory disorders. Our aim was to analyse PMN elastase in idiopathic inflammatory myopathies (IIMs) and its association with disease activity.
Siyu Wu, Wanchan Peng, Yunli Zhang, Jingjing Guo, Jinfang Fu, Wei Wang   +5 more
doaj   +1 more source

Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.

Marine Drugs, 2011
Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established
Zhi-Hong Wen, Jyh-Horng Sheu, Ping-Jyun Sung, Yang-Chang Wu, Jui-Hsin Su, Tsong-Long Hwang, Shih-Yao Kao   +6 more
doaj   +1 more source

Glycerol and Natural Deep Eutectic Solvents Extraction for Preparation of Luteolin-Rich Jasione montana Extracts with Cosmeceutical Activity

Metabolites, 2022
Jasione montana is a plant from the family Campanulaceae rich in phenols with health-beneficial properties such as luteolin (LUT) derivatives. In this work, a glycerol-based ultrasound-assisted extraction method was developed and optimized for in total ...
Aleksandra Maria Juszczak, Marijan Marijan, Lejsa Jakupović, Monika Tomczykowa, Michał Tomczyk, Marijana Zovko Končić   +5 more
doaj   +1 more source