Results 41 to 50 of about 6,297 (122)

Optimization of PET Expression Vector for Fusion of Recombinant Protein and Elastin-Like Polypeptide Biopolymer

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2019
Background and Aim recombinant DNA technique is a powerful and appropriate method for the production of protein biopolymers with specificity in amino acid sequence and spatial chemistry.
Mohammad Reza Soleyman   +3 more
doaj  

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

open access: yesJournal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon   +12 more
wiley   +1 more source

Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song   +4 more
wiley   +1 more source

Functional Differentiation of Type II and Type I Collagen Articular Models in Synovial Fluid Film Formation and Recombinant Equine Lubricin Retention

open access: yesAdvanced Functional Materials, Volume 36, Issue 77, 24 September 2026.
Collagen II coatings support the formation of synovial fluid nanofilms, while collagen I coatings do not. Both bind recombinant equine lubricin similarly. These findings may help explain articular cartilage surface joint dysfunction, inform biomaterial design for synovial joint repair, and expand on lubricin‐based osteoarthritis therapies.
Diego R. Jaramillo Pinto   +12 more
wiley   +1 more source

Targeting prostate cancer cells with hybrid elastin-like polypeptide/liposome nanoparticles

open access: yesInternational Journal of Nanomedicine, 2018
Wei Zhang,1 Yunmei Song,1 Preethi Eldi,1 Xiuli Guo,2 John D Hayball,1,3 Sanjay Garg,1 Hugo Albrecht1 1Centre for Pharmaceutical Innovation and Development, Centre for Drug Discovery and Development, Experimental Therapeutics Laboratory, Sansom Institute
Zhang W   +6 more
doaj  

Engineering tunable Elastin-Like Polypeptide/PEGDA composite hydrogels as injectable soft tissue fillers

open access: yesMaterials & Design
Soft tissue augmentation is widely used for cosmetic and reconstructive indications, requiring void filler materials that can be delivered minimally invasively while maintaining structural stability and tissue-like mechanics.
Mahsa Jamadi Khiabani   +2 more
doaj   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

open access: yesAdvanced Materials Technologies, Volume 11, Issue 18, 18 September 2026.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le   +4 more
wiley   +1 more source

Extending the Three-Dimensional Culture of Adipocytes Through Surface Coatings

open access: yesBioengineering
To mimic the important features of progressing adiposity, in vitro adipose cell culture models must allow gradual intracellular fat accumulation in the three-dimensional (3D) arrangement of adipose-derived stem cells (ASCs) over a long-term culture ...
Sheetal Chowdhury   +5 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

open access: yesBMEMat, Volume 4, Issue 3, September 2026.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang   +13 more
wiley   +1 more source

Mechanistic Pathways of Wound Healing: From Hemostasis to Scar‐Free Regeneration

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Wound healing is the critical process regulated through a harmonious coordination of cellular, molecular, pathological, and systemic communications. Normally, healing occurs in four overlapping phases, which are modified and controlled by various growth factor interactions and signaling pathways.
Devadass Jessy Mercy   +2 more
wiley   +1 more source

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