Results 41 to 50 of about 36,056 (184)
Process Intensification for an Insect Antimicrobial Peptide Elastin-Like Polypeptide Fusion Produced in Redox-Engineered Escherichia coli [PDF]
Frontiers in Bioengineering and Biotechnology, 2019 Peptides and proteins containing disulfide bonds can be produced in Escherichia coli by targeting the oxidizing periplasm, co-expressing isomerases or chaperons, refolding from inclusion bodies, or by using redox-engineered E. coli strains.
Mathias Joachim +7 more
doaj +2 more sources
Pathway‐Dependent Co‐Assembly of Elastin‐Like Polypeptides [PDF]
Small, 2021 AbstractIn natural systems, temperature‐induced assembly of biomolecules can lead to the formation of distinct assembly states, created out of the same set of starting compounds, based on the heating trajectory followed. Until now it has been difficult to achieve similar behavior in synthetic polymer mixtures.
Jan Pille +8 more
openaire +2 more sources
Biodegradation of elastin‐like polypeptide nanoparticles [PDF]
Protein Science, 2012 AbstractProtein polymers are repetitive polypeptides produced by ribosomal biosynthetic pathways; furthermore, they offer emerging opportunities in drug and biopharmaceutical delivery. As for any polymer, biodegradation is one of the most important determinants affecting how a protein polymer can be utilized in the body.
Mihir, Shah +5 more
openaire +2 more sources
Construction and application of elastin like polypeptide containing IL-4 receptor targeting peptide. [PDF]
PLoS ONE, 2013 Various human solid tumors highly express IL-4 receptors which amplify the expression of some of anti-apoptotic proteins, preventing drug-induced cancer cell death. Thus, IL-4 receptor targeted drug delivery can possibly increase the therapeutic efficacy
Vijaya Sarangthem +8 more
doaj +1 more source
Corneal Penetrating Elastin-Like Polypeptide Carriers [PDF]
Journal of Ocular Pharmacology and Therapeutics, 2016 Elastin-like polypeptide (ELP) is a bioengineered protein widely applied as a drug carrier due to its biocompatibility and amenability to modification with cell-penetrating peptides (CPPs) and therapeutic agents. The purpose of this study was to determine whether topically applied ELP or CPP-fused ELPs penetrate the corneal barrier.In vitro binding and
Eric M, George +4 more
openaire +2 more sources
Chain Stiffness of Elastin-Like Polypeptides [PDF]
Biomacromolecules, 2010 The hydrodynamic radii of a series of genetically engineered monodisperse elastin like polypeptides (ELP) was determined by dynamic light scattering in aqueous solution as function of molar mass. Utilizing the known theoretical expression for the hydrodynamic radius of wormlike chains, the Kuhn statistical segment length was determined to be lk = 2.1 ...
Fluegel, Sabine +4 more
openaire +2 more sources
Elastin-Like Polypeptide Based Hydroxyapatite Bionanocomposites [PDF]
Biomacromolecules, 2011 In nature, organic matrix macromolecules play a critical role in enhancing the mechanical properties of biomineralized composites such as bone and teeth. Designing artificial matrix analogues is promising but challenging because relatively little is known about how natural matrix components function.
Eddie, Wang +2 more
openaire +2 more sources
Elastin-like polypeptide-based micelles as a promising platform in nanomedicine.
Journal of Controlled Release, 2022 New and improved nanomaterials are constantly being developed for biomedical purposes. Nanomaterials based on elastin-like polypeptides (ELPs) have increasingly shown potential over the past two decades.
Jolinde van Strien +4 more
semanticscholar +1 more source
Journal of Nanobiotechnology, 2023 Elastin-like polypeptides (ELPs) are thermally responsive biopolymers derived from natural elastin. These peptides have a low critical solution temperature phase behavior and can be used to prepare stimuli-responsive biomaterials.
Yingshu Guo +4 more
doaj +1 more source
Advanced Science, 2021 Design of reversible organelle‐like microcompartments formed by liquid–liquid phase separation in cell‐mimicking entities has significantly advanced the bottom‐up construction of artificial eukaryotic cells.
Hang Zhao +5 more
doaj +1 more source