Results 21 to 30 of about 14,557 (201)
Bioorthogonal Elastin-like Polypeptide Scaffolds for Immunoassay Enhancement [PDF]
ACS Applied Materials & Interfaces, 2018 Artificial multiprotein complexes are sought after reagents for biomolecular engineering. A current limiting factor is the paucity of molecular scaffolds which allow for site-specific multicomponent assembly. Here, we address this limitation by synthesizing bioorthogonal elastin-like polypeptide (ELP) scaffolds containing periodic noncanonical l ...
Duy Tien Ta +2 more
openaire +4 more sources
Molecules, 2009 A well characterized, peptide derivative of bovine lactoferrin, L12, has been shown to possess anticancer properties in multiple cell lines. However, adverse side effects in normal tissues and poor plasma kinetics that hinder the clinical effectiveness ...
Emily Thomas +2 more
doaj +3 more sources
Circumventing Doxorubicin Resistance Using Elastin-like Polypeptide Biopolymer-Mediated Drug Delivery. [PDF]
Int J Mol Sci, 2022 Dragojevic S, Turner L, Raucher D.
europepmc +2 more sources
Elastin-like Polypeptide-Based Bioink: A Promising Alternative for 3D Bioprinting
, 2021 Three-dimensional (3D) bioprinting offers a great alternative to traditional techniques in tissue reconstruction, based on seeding cells manually into a scaffold, to better reproduce organs’ complexity.
Jean-Philippe Belaïdi (11668197) +6 more
core +3 more sources
Elastin-Like Polypeptides for Biomedical Applications [PDF]
Annual Review of Biomedical Engineering, 2020 Elastin-like polypeptides (ELPs) are stimulus-responsive biopolymers derived from human elastin. Their unique properties—including lower critical solution temperature phase behavior and minimal immunogenicity—make them attractive materials for a variety of biomedical applications.
Anastasia K, Varanko +2 more
openaire +2 more sources
Pathway‐Dependent Co‐Assembly of Elastin‐Like Polypeptides [PDF]
Small, 2021 AbstractIn natural systems, temperature‐induced assembly of biomolecules can lead to the formation of distinct assembly states, created out of the same set of starting compounds, based on the heating trajectory followed. Until now it has been difficult to achieve similar behavior in synthetic polymer mixtures.
Jan Pille +8 more
openaire +2 more sources
Novel Protein Therapeutics Created Using the Elastin-Like Polypeptide Platform.
Physiology (Bethesda), 2021 Bidwell GL.
europepmc +2 more sources
Biodegradation of elastin‐like polypeptide nanoparticles [PDF]
Protein Science, 2012 AbstractProtein polymers are repetitive polypeptides produced by ribosomal biosynthetic pathways; furthermore, they offer emerging opportunities in drug and biopharmaceutical delivery. As for any polymer, biodegradation is one of the most important determinants affecting how a protein polymer can be utilized in the body.
Mihir, Shah +5 more
openaire +2 more sources
Elastin-like polypeptides in drug delivery [PDF]
Advanced Drug Delivery Reviews, 2016 The use of recombinant elastin-like materials, or elastin-like recombinamers (ELRs), in drug-delivery applications is reviewed in this work. Although ELRs were initially used in similar ways to other, more conventional kinds of polymeric carriers, their unique properties soon gave rise to systems of unparalleled functionality and efficiency, with the ...
Rodríguez Cabello, José Carlos +3 more
openaire +2 more sources
Construction and application of elastin like polypeptide containing IL-4 receptor targeting peptide. [PDF]
PLoS ONE, 2013 Various human solid tumors highly express IL-4 receptors which amplify the expression of some of anti-apoptotic proteins, preventing drug-induced cancer cell death. Thus, IL-4 receptor targeted drug delivery can possibly increase the therapeutic efficacy
Vijaya Sarangthem +8 more
doaj +1 more source