Results 41 to 50 of about 4,594,965 (203)

Elastin-Based Thermoresponsive Shape-Memory Hydrogels

, 2020
A shape-memory hydrogel is a programmable hydrogel material that can store specific shapes and execute functions in response to stimuli. In this report, we developed shape-memory hydrogels by creating double-network polymeric structures using a ...
Seung-Wuk Lee, Tao Wang, Yuancheng Zhang, Tao Wang (12008), Yuancheng Zhang (2541988), Malav S. Desai, Malav S. Desai (1839700), Seung-Wuk Lee (1487140)   +7 more
core   +5 more sources

High-yield recombinant expression and purification of marginally soluble, short elastin-like polypeptides

BioTechniques, 2016
The protocol described here is designed as an extension of existing techniques for creating elastin-like polypeptides. It allows for the expression and purification of elastin-like polypeptide (ELP) constructs that are poorly expressed or have very low ...
Markian S. Bahniuk, Abdullah K. Alshememry, Larry D. Unsworth   +2 more
doaj   +1 more source

Biophysical Characterization of an Elastin-Like-Polypeptide [PDF]

Biophysical Journal, 2011
Perhaps the largest impediment in cancer therapies has been the inability to effectively target systemically delivered therapeutics to cancerous cells. A recent and novel approach to this problem has been to chemically conjugate the therapeutic to an Elastin-Like-Polypeptide (ELP).
Lyons, Daniel, Bidwell, Gene L., Kramer, Wolfgang H., Raucher, Drazen, Correia, John J.   +4 more
openaire   +1 more source

Evaluation of Elastin-Like Polypeptides for Tumor Targeted Delivery of Doxorubicin to Glioblastoma

Molecules, 2019
To increase treatment efficiency for glioblastoma, we have developed a system to selectively deliver chemotherapeutic doxorubicin (Dox) to Glioblastoma (GBM) tumors.
Sonja Dragojevic, Rebecca Mackey, Drazen Raucher   +2 more
doaj   +1 more source

Elastin-like Polypeptide Diblock Copolymers Self-Assemble into Weak Micelles [PDF]

, 2015
The self-assembly of synthetic diblock copolymers has been extensively studied experimentally and theoretically. In contrast, self-assembly of polypeptide diblock copolymers has so far been mostly studied experimentally.
Rubinstein, Michael, Hassouneh, Wafa, Michael Rubinstein (1422745), Wafa Hassouneh (1670089), Ekaterina B. Zhulina (1670092), Ashutosh Chilkoti (1266378), Chilkoti, Ashutosh, Zhulina, Ekaterina B.   +7 more
core   +1 more source

Polyproline: A Synthetic Polypeptide With Unique Properties

Angewandte Chemie, EarlyView.
Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec, Josué M. Galindo, Colin Bonduelle, Andreas Heise   +3 more
wiley   +2 more sources

The application of elastin-like peptides in cancer, tissue engineering and ocular disease

OpenNano, 2023
Elastin-like polypeptides (ELPs) are macromolecular biopolymers composed of natural amino acids. ELPs can be prepared by genetic engineering so that their amino acid sequences and molecular weight can be precisely manipulated.
Dabo Jiang, Yang Yang, Xiuyi Yang, Boxuan Wang, Wenxuan Fan, Yuchen Liu, Xiaofei Xin, Lifang Yin   +7 more
doaj   +1 more source

Emerging Role of Elastin-Like Polypeptides in Regenerative Medicine

Advances in Wound Care, 2021
Significance: Wound dressing based on naturally derived polymer provides a useful platform for treatment of skin injuries. Owing to the high mechanical strength and tunable structural and physicochemical properties of human elastin-like polypeptides (ELPs), they may be used as excellent materials for fabricating
Vijaya, Sarangthem, Thoudam Debraj, Singh, Amit Kumar, Dinda   +2 more
openaire   +2 more sources

Elastin-Based Rubber-Like Hydrogels

, 2016
We developed rubber-like elastomeric materials using a natural elastin derived sequence and genetic engineering to create precisely defined elastin-like polypeptides.
Malav S. Desai (2824337), Eddie Wang (1512190), Tae Won Chung (2824343), Kyle Joyner (2824340), Seung-Wuk Lee (1487140), Hyo-Eon Jin (1487137)   +5 more
core   +1 more source

Analysis of the molecular mobility of collagen and elastin in safe, atheromatous and aneurysmal aortas [PDF]

, 2012
Aim of the study : In this study, we propose to use a thermal technique, Differential Scanning Calorimetry (DSC) to follow the evolution of elastin and collagen in safe and pathological cardiovascular tissues.
Gargiulo, Mauro, Stella, Andréa, A. Stella, M. Gargiulo, Gandaglia, Alessandro, Samouillan, Valérie, Spina, Michel, V. SAMOUILLAN, Degani, Annamaria, Dandurand, Jany, C. LACABANNE, J. DANDURAND, A. GANDAGLIA, Lacabanne, Colette, SPINA, MAURO, M. Spina, A. DEGANI   +16 more
core   +1 more source