Results 51 to 60 of about 4,594,965 (203)
Elastin-like Recombinamer Hydrogels as Platforms for Breast Cancer Modeling
, 2023 The involvement of the extracellular matrix (ECM) in tumor progression has motivated the development of biomaterials mimicking the tumor ECM to develop more predictive cancer models.
Soledad Perez-Amodio (12913320) +6 more
core +1 more source
Selective Tuning of Elastin-like Polypeptide Properties via Methionine Oxidation [PDF]
, 2017 International audienceWe have designed and prepared a recombinant elastin-like polypeptide (ELP) containing precisely positioned methionine residues, and performed the selective and complete oxidation of its methionine thioether groups to both sulfoxide ...
Bathany, Katell +16 more
core +2 more sources
Aggregation-Dispersion Chromatography: Application of Elastin-like Polypeptides
SeparationsProtein purification is a crucial step for various downstream applications like drug development, antibody preparation, and structure determination. The constant pursuit is for methods that are more efficient and cost-effective.
Han Bin Shin, Young Kee Chae
doaj +1 more source
An Elastin-Derived Self-Assembling Polypeptide [PDF]
, 2013 Elastin is an extracellular matrix protein responsible for the elastic properties of organs and tissues, the elastic properties being conferred to the protein by the presence of elastic fibers.
PEPE, Antonietta, BOCHICCHIO, Brigida
core +1 more source
Influence of elastin-like polypeptide and hydrophobin on recombinant hemagglutinin accumulations in transgenic tobacco plants. [PDF]
PLoS ONE, 2014 Fusion protein strategies are useful tools to enhance expression and to support the development of purification technologies. The capacity of fusion protein strategies to enhance expression was explored in tobacco leaves and seeds.
Hoang Trong Phan +8 more
doaj +1 more source
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Advanced Science, EarlyView.Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
Secreted production of an elastin-like polypeptide by Pichia pastoris [PDF]
Applied Microbiology and Biotechnology, 2009 Elastin-like polypeptides (ELPs) are biocompatible designer polypeptides with inverse temperature transition behavior in solution. They have a wide variety of possible applications and a potential medical importance. Currently, production of ELPs is done at lab scale in Escherichia coli shake flask cultures. With a view to future large scale production,
Schipperus, R. +4 more
openaire +3 more sources
Biotechnology for Biofuels, 2019 Background In the enzymatic conversion of biomass, it becomes an important issue to efficiently and cost-effectively degrade cellulose into fermentable glucose. β-Glucosidase (Bgluc), an essential member of cellulases, plays a critical role in cellulosic
Yang Zhou +10 more
doaj +1 more source
Advanced Science, 2023 L‐Asparaginase (ASP) is well‐known for its excellent efficacy in treating hematological malignancies. Unfortunately, the intrinsic shortcomings of ASP, namely high immunogenicity, severe toxicity, short half‐life, and poor stability, restrict its ...
Sanke Zhang +4 more
doaj +1 more source
Engineered elastin-like polypeptides: An efficient platform for enhanced cancer treatment
Frontiers in Pharmacology, 2023 Drug delivery systems (DDSs) have recently gained widespread attention for improving drug loading and delivery efficiency in treating many cancers. Elastin-like polypeptides (ELPs) are synthetic peptides derived from a precursor of elastin (tropoelastin),
Aiguo Jiang +4 more
doaj +1 more source