Results 1 to 10 of about 142 (64)

Glutathionylated and Fe–S cluster containing hMIA40 (CHCHD4) regulates ROS and mitochondrial complex III and IV activities of the electron transport chain

open access: goldRedox Biology, 2020
Human MIA40, an intermembrane space (IMS) import receptor of mitochondria harbors twin CX9C motifs for stability while its CPC motif is known to facilitate the import of IMS bound proteins.
Venkata Ramana Thiriveedi   +6 more
doaj   +2 more sources

APOE expression and secretion are modulated by mitochondrial dysfunction

open access: yeseLife, 2023
Mitochondria influence cellular function through both cell-autonomous and non-cell autonomous mechanisms, such as production of paracrine and endocrine factors.
Meghan E Wynne   +26 more
doaj   +1 more source

New insight into the mechanism of mitochondrial cytochrome c function. [PDF]

open access: yesPLoS ONE, 2017
We investigate functional role of the P76GTKMIFA83 fragment of the primary structure of cytochrome c. Based on the data obtained by the analysis of informational structure (ANIS), we propose a model of functioning of cytochrome c. According to this model,
Rita V Chertkova   +9 more
doaj   +1 more source

Mitochondrial Function and Parkinson’s Disease: From the Perspective of the Electron Transport Chain

open access: yesFrontiers in Molecular Neuroscience, 2021
Parkinson’s disease (PD) is known as a mitochondrial disease. Some even regarded it specifically as a disorder of the complex I of the electron transport chain (ETC).
Jeng-Lin Li   +9 more
doaj   +1 more source

ETMB-RBF: discrimination of metal-binding sites in electron transporters based on RBF networks with PSSM profiles and significant amino acid pairs. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Cellular respiration is the process by which cells obtain energy from glucose and is a very important biological process in living cell. As cells do cellular respiration, they need a pathway to store and transport electrons, the electron ...
Yu-Yen Ou, Shu-An Chen, Sheng-Cheng Wu
doaj   +1 more source

Evaluation of functioning of mitochondrial electron transport chain with NADH and FAD autofluorescence [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2016
We prove the feasibility of evaluation of mitochondrial electron transport chain function in isolated mitochondria of smooth muscle cells of rats from uterus using fluorescence of NADH and FAD coenzymes. We found the inversely directed changes in FAD and
H. V. Danylovych
doaj   +1 more source

An essential role for an Fe-S cluster protein in the cytochrome c oxidase complex of Toxoplasma parasites.

open access: yesPLoS Pathogens, 2023
The mitochondrial electron transport chain (ETC) of apicomplexan parasites differs considerably from the ETC of the animals that these parasites infect, and is the target of numerous anti-parasitic drugs.
Rachel A Leonard   +4 more
doaj   +1 more source

A Biophysical Model of the Mitochondrial Respiratory System and Oxidative Phosphorylation. [PDF]

open access: yesPLoS Computational Biology, 2005
A computational model for the mitochondrial respiratory chain that appropriately balances mass, charge, and free energy transduction is introduced and analyzed based on a previously published set of data measured on isolated cardiac mitochondria.
Daniel A Beard
doaj   +2 more sources

Is impaired energy production a novel insight into the pathogenesis of pyridoxine-dependent epilepsy due to biallelic variants in ALDH7A1?

open access: yesPLoS ONE, 2021
BackgroundPyridoxine-dependent epilepsy (PDE) is due to biallelic variants in ALDH7A1 (PDE-ALDH7A1). ALDH7A1 encodes α-aminoadipic semialdehyde dehydrogenase in lysine catabolism.
Anastasia Minenkova   +7 more
doaj   +1 more source

Male and Female Mitochondria Respond Differently after Exercising in Acute Hypoxia

open access: yesBiomedicines, 2023
The use of hypoxic devices among athletes who train in normobaric hypoxia has become increasingly popular; however, the acute effects on heart and brain metabolism are not yet fully understood.
Ylenia Lai   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy