Results 1 to 10 of about 95,409 (213)

Astragaloside IV Inhibits Mitochondrial-Dependent Apoptosis of the Dorsal Root Ganglion in Diabetic Peripheral Neuropathy Rats Through Modulation of the SIRT1/p53 Signaling Pathway

Diabetes, Metabolic Syndrome and Obesity, 2021
Ying Ben,1,2,* Juan Hao,1,* Zhihong Zhang,1,2 Yunzhao Xiong,1 Cuijuan Zhang,1,2 Yi Chang,1,2 Fan Yang,1,2 Hui Li,1,2 Tianya Zhang,1 Xiangting Wang,1,2 Qingyou Xu1,2 1Hebei University of Chinese Medicine, Shijiazhuang, Hebei, People’s Republic of ...
Ben Y, Hao J, Zhang Z, Xiong Y, Zhang C, Chang Y, Yang F, Li H, Zhang T, Wang X, Xu Q   +10 more
doaj  

Sodium fluoride causes oxidative damage to silkworm (Bombyx mori) testis by affecting the oxidative phosphorylation pathway

Ecotoxicology and Environmental Safety, 2021
Bombyx mori was used to study the molecular mechanism of fluoride induced reproductive toxicity. In our previous study, we confirmed the physiological and biochemical effects of NaF on reproductive toxicity, and we found that the molecular mechanism of ...
Wenchao Tang, Yuanyuan Xiao, Yaohang Long, Yaofeng Li, Fang Peng, Can Zhu, Tinggui He, Didong Lou, Yong Zhu   +8 more
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Streptozotocin-Induced Adaptive Modification of Mitochondrial Supercomplexes in Liver of Wistar Rats and the Protective Effect of Moringa oleifera Lam

Biochemistry Research International, 2018
The increasing prevalence of diabetes continues to be a major health issue worldwide. Alteration of mitochondrial electron transport chain is a recognized hallmark of the diabetic-associated decline in liver bioenergetics; however, the molecular events ...
María Alejandra Sánchez-Muñoz, Mónica Andrea Valdez-Solana, Mara Ibeth Campos-Almazán, Óscar Flores-Herrera, Mercedes Esparza-Perusquía, Sofia Olvera-Sánchez, Guadalupe García-Arenas, Claudia Avitia-Domínguez, Alfredo Téllez-Valencia, Erick Sierra-Campos   +9 more
doaj   +1 more source

Structural study of Topoisomerase IV-DNA-Levofloxacin complexes from Streptococcus pneumoniae [PDF]

E3S Web of Conferences, 2019
S. pneumoniae is an important pathogen causing pulmonary infection, acute otitis media and purulent meningitis in infants and children. Type II topoisomerases are enzymes that play essential roles in DNA replication, chromosome segregation and ...
Wang Xilan
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Cryptococcus neoformans Mar1 function links mitochondrial metabolism, oxidative stress, and antifungal tolerance

Frontiers in Physiology, 2023
Introduction: Microbial pathogens undergo significant physiological changes during interactions with the infected host, including alterations in metabolism and cell architecture.
Calla L. Telzrow, Calla L. Telzrow, Shannon Esher Righi, Jackson M. Cathey, Joshua A. Granek, J. Andrew Alspaugh, J. Andrew Alspaugh   +6 more
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Different Effects of SSRIs, Bupropion, and Trazodone on Mitochondrial Functions and Monoamine Oxidase Isoform Activity

Antioxidants, 2023
Mitochondrial dysfunction is involved in the pathophysiology of psychiatric and neurodegenerative disorders and can be used as a modulator and/or predictor of treatment responsiveness.
Matej Ľupták, Zdeněk Fišar, Jana Hroudová   +2 more
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Enhanced Skeletal Muscle Oxidative Capacity and Capillary-to-Fiber Ratio Following Moderately Increased Testosterone Exposure in Young Healthy Women

Frontiers in Physiology, 2020
Background: Recently, it was shown that exogenously administered testosterone enhances endurance capacity in women. In this study, our understanding on the effects of exogenous testosterone on key determinants of oxygen transport and utilization in ...
Daniele A. Cardinale, Daniele A. Cardinale, Oscar Horwath, Jona Elings-Knutsson, Jona Elings-Knutsson, Torbjörn Helge, Manne Godhe, Stéphane Bermon, Marcus Moberg, Mikael Flockhart, Filip J. Larsen, Angelica Lindén Hirschberg, Angelica Lindén Hirschberg, Björn Ekblom   +13 more
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Euglena’s atypical respiratory chain adapts to the discoidal cristae and flexible metabolism

Nature Communications
Euglena gracilis, a model organism of the eukaryotic supergroup Discoba harbouring also clinically important parasitic species, possesses diverse metabolic strategies and an atypical electron transport chain.
Zhaoxiang He, Mengchen Wu, Hongtao Tian, Liangdong Wang, Yiqi Hu, Fangzhu Han, Jiancang Zhou, Yong Wang, Long Zhou   +8 more
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Unique, Diverged, and Conserved Mitochondrial Functions Influencing Candida albicans Respiration

mBio, 2019
Candida albicans is an opportunistic fungal pathogen of major clinical concern. The virulence of this pathogen is intimately intertwined with its metabolism.
Nuo Sun, Rebecca S. Parrish, Richard A. Calderone, William A. Fonzi   +3 more
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Adapting High-Resolution Respirometry to Glucose-Limited Steady State Mycelium of the Filamentous Fungus Penicillium ochrochloron: Method Development and Standardisation.

PLoS ONE, 2016
Fungal electron transport systems (ETS) are branched, involving alternative NADH dehydrogenases and an alternative terminal oxidase. These alternative respiratory enzymes were reported to play a role in pathogenesis, production of antibiotics and ...
Christoph W Schinagl, Pamela Vrabl, Wolfgang Burgstaller   +2 more
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