Results 11 to 20 of about 10,822,815 (272)

Advanced modeling of bioenergetics in the mitochondrial electron transport chain with emphasis on complex IV

Alzheimer's & Dementia
AbstractBackgroundMitochondrial bioenergetics are essential for cellular function, specifically the intricacies of the electron transport chain (ETC), with Complex IV playing a crucial role in unraveling the mechanisms governing energy production. Mathematical models offer a valuable approach to simulate these complex processes, providing insights into
Keleshteri, Marzieh Eini, Cadonic, Chris D, Ghafourian, Taravat, Thomson, Ella, Snow, Wanda M, McAllister, Danielle, Djordjevic, Jelena, Chowdhury, Subir K Roy, Fernyhough, Paul, Fiege, Jason D, Portet, Stephanie D, Albensi, Benedict C   +11 more
openaire   +2 more sources

Efficient Electron Hopping Transport through Azurin-Based Junctions [PDF]

, 2023
We conducted a theoretical study into electron transport through junctions of the blue-copper azurin from Pseudomonas aeruginosa. We found that single-site hopping can lead to either higher or lower current values compared to fully-coherent transport ...
Rubén, Pérez, Carlos, Roldán-Piñero, Linda Angela, Zotti, Carlos, Romero-Muñiz, José Guilherme , Vilhena, Ismael, Díez-Pérez, Juan Carlos, Cuevas   +6 more
core   +4 more sources

A Biophysical Model of the Mitochondrial Respiratory System and Oxidative Phosphorylation. [PDF]

PLoS Computational Biology, 2005
A computational model for the mitochondrial respiratory chain that appropriately balances mass, charge, and free energy transduction is introduced and analyzed based on a previously published set of data measured on isolated cardiac mitochondria.
Daniel A Beard
doaj   +2 more sources

Male and Female Mitochondria Respond Differently after Exercising in Acute Hypoxia

Biomedicines, 2023
The use of hypoxic devices among athletes who train in normobaric hypoxia has become increasingly popular; however, the acute effects on heart and brain metabolism are not yet fully understood.
Ylenia Lai, Francesco Loy, Michela Isola, Roberta Noli, Andrea Rinaldi, Carla Lobina, Romina Vargiu, Flaminia Cesare Marincola, Raffaella Isola   +8 more
doaj   +1 more source

Structure of a bacterial type IV secretion core complex at subnanometre resolution [PDF]

, 2013
Type IV secretion (T4S) systems are able to transport DNAs and/or proteins through the membranes of bacteria. They form large multiprotein complexes consisting of 12 proteins termed VirB1-11 and VirD4.
Steyaert, J., Pardon, E, Savva, CG, Lian, Pei W., Fronzes, Remi, Waksman, Gabriel, Orlova, Elena, Orlova, EV, Remaut, Han, Chandran, Vidya, Fronzes, R, Laeremans, T., Chandran, V, Lian, PW, Steyaert, J, Laeremans, T, Rivera-Calzada, A., Remaut, H, Pardon, E., Waksman, G, Rivera-Calzada, A, Savva, Christos G.   +21 more
core   +1 more source

Electron Transport Chain Complex II Regulates Steroid Metabolism

iScience, 2020
Summary: The first steroidogenic enzyme, cytochrome P450-side-chain-cleavage (SCC), requires electron transport chain (ETC) complexes III and IV to initiate steroid metabolic processes for mammalian survival.
Himangshu S. Bose, Brendan Marshall, Dilip K. Debnath, Elizabeth W. Perry, Randy M. Whittal   +4 more
doaj   +1 more source

Enhanced Electron Transfer Reactivity of a Nonheme Iron(IV)-Imido Complex as Compared to the Iron(IV)-Oxo Analogue

, 2021
Reactions of N,N-dimethylaniline (DMA) with nonheme iron(IV)-oxo and iron(IV)-tosylimido complexes occur via different mechanisms, such as an N-demethylation of DMA by a nonheme iron(IV)-oxo complex or an electron transfer dimerization of DMA by a ...
이용민, 남원우, Shunichi Fukuzumi, 정지은, Kei Okubo   +4 more
core   +1 more source

Endurance exercise training in pulmonary hypertension increases skeletal muscle electron transport chain supercomplex assembly

Pulmonary Circulation, 2020
Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexes are
Danielle J. McCullough, Nouaying Kue, Thomas Mancini, Alexander Vang, Richard T. Clements, Gaurav Choudhary   +5 more
doaj   +1 more source

Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder

Translational Psychiatry, 2021
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with unique changes in mitochondrial metabolism, including elevated respiration rates and morphological alterations.
Richard E. Frye, Loïc Lionnard, Indrapal Singh, Mohammad A. Karim, Hanane Chajra, Mathilde Frechet, Karima Kissa, Victor Racine, Amrit Ammanamanchi, Patrick John McCarty, Leanna Delhey, Marie Tippett, Shannon Rose, Abdel Aouacheria   +13 more
doaj   +1 more source

Electron-transfer properties of a nonheme manganese(iv)-oxo complex acting as a stronger one-electron oxidant than the iron(iv)-oxo analogue

, 2021
Electron-transfer properties of a nonheme Mn(iv)-oxo complex, [(Bn-TPEN)MnIV(O)]2+, reveals that Mn(iv)-oxo complex acts as a stronger one-electron oxidant than the Fe(iv)-oxo analogue. As a result, an electron transfer process in N-dealkylation has been
이용민, 남원우, Shunichi Fukuzumi
core   +1 more source