Results 11 to 20 of about 102,377 (268)
Efficient Electron Hopping Transport through Azurin-Based Junctions [PDF]
, 2023 We conducted a theoretical study into electron transport through junctions of the blue-copper azurin from Pseudomonas aeruginosa. We found that single-site hopping can lead to either higher or lower current values compared to fully-coherent transport ...
Rubén, Pérez +6 more
core +3 more sources
APOE expression and secretion are modulated by mitochondrial dysfunction
eLife, 2023 Mitochondria influence cellular function through both cell-autonomous and non-cell autonomous mechanisms, such as production of paracrine and endocrine factors.
Meghan E Wynne +26 more
doaj +1 more source
NDUFA4 Is a Subunit of Complex IV of the Mammalian Electron Transport Chain [PDF]
Cell Metabolism, 2012 The oxidative phosphorylation system is one of the best-characterized metabolic pathways. In mammals, the protein components and X-ray structures are defined for all complexes except complex I. Here, we show that NDUFA4, formerly considered a constituent of NADH Dehydrogenase (CI), is instead a component of the cytochrome c oxidase (CIV).
Balsa, E. +6 more
openaire +3 more sources
New insight into the mechanism of mitochondrial cytochrome c function. [PDF]
PLoS ONE, 2017 We investigate functional role of the P76GTKMIFA83 fragment of the primary structure of cytochrome c. Based on the data obtained by the analysis of informational structure (ANIS), we propose a model of functioning of cytochrome c. According to this model,
Rita V Chertkova +9 more
doaj +1 more source
ETMB-RBF: discrimination of metal-binding sites in electron transporters based on RBF networks with PSSM profiles and significant amino acid pairs. [PDF]
PLoS ONE, 2013 BACKGROUND: Cellular respiration is the process by which cells obtain energy from glucose and is a very important biological process in living cell. As cells do cellular respiration, they need a pathway to store and transport electrons, the electron ...
Yu-Yen Ou, Shu-An Chen, Sheng-Cheng Wu
doaj +1 more source
Ascorbate Biosynthesis in Mitochondria Is Linked to the Electron Transport Chain between Complexes III and IV [PDF]
Plant Physiology, 2000 Abstract Ascorbic acid is synthesized from galactono-γ-lactone (GL) in plant tissues. An improved extraction procedure involving ammonium sulfate precipitation of membrane proteins from crude leaf homogenates yielded a simple, quick method for determining tissue activities of galactono-γ-lactone dehydrogenase (GLDH).
Bartoli, Carlos Guillermo +2 more
openaire +3 more sources
PLoS Pathogens, 2023 The mitochondrial electron transport chain (ETC) of apicomplexan parasites differs considerably from the ETC of the animals that these parasites infect, and is the target of numerous anti-parasitic drugs.
Rachel A Leonard +4 more
doaj +1 more source
PLoS ONE, 2021 BackgroundPyridoxine-dependent epilepsy (PDE) is due to biallelic variants in ALDH7A1 (PDE-ALDH7A1). ALDH7A1 encodes α-aminoadipic semialdehyde dehydrogenase in lysine catabolism.
Anastasia Minenkova +7 more
doaj +1 more source
A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation. [PDF]
PLoS Computational Biology, 2005 A computational model for the mitochondrial respiratory chain that appropriately balances mass, charge, and free energy transduction is introduced and analyzed based on a previously published set of data measured on isolated cardiac mitochondria.
Daniel A Beard
doaj +2 more sources
Male and Female Mitochondria Respond Differently after Exercising in Acute Hypoxia
Biomedicines, 2023 The use of hypoxic devices among athletes who train in normobaric hypoxia has become increasingly popular; however, the acute effects on heart and brain metabolism are not yet fully understood.
Ylenia Lai +8 more
doaj +1 more source