Results 31 to 40 of about 10,822,815 (272)

Brownian dynamics simulation of cytochrome c diffusion and binding with cytochrome c1 in mitochondrial crista [PDF]

ITM Web of Conferences, 2020
Cytochrome c (Cc) protein shuttles electrons from respiratory chain complex III — from cytochrome c1 (Cc1) subunit — to complex IV during oxidative phosphorylation, in intermembrane space of mitochondria and cristae lumen.
Abaturova Anna M., Brazhe Nadezda A., Kovalenko Ilya B., Riznichenko Galina Yu, Rubin Andrei B.   +4 more
doaj   +1 more source

Hyperoxia decreases glycolytic capacity, glycolytic reserve and oxidative phosphorylation in MLE-12 cells and inhibits complex I and II function, but not complex IV in isolated mouse lung mitochondria.

PLoS ONE, 2013
High levels of oxygen (hyperoxia) are frequently used in critical care units and in conditions of respiratory insufficiencies in adults, as well as in infants.
Kumuda C Das
doaj   +1 more source

Cytochromes c550, c552, c1 in the electron transport network of Paracoccus denitrificans: redundant or subtly different in function? [PDF]

, 2001
Paracoccus denitrificans strains with mutations in the genes encoding the cytochrome c550, c552, or c1 and in combinations of these genes were constructed, and their growth characteristics were determined.
Spanning, R.J.M., van, Westerhoff, H.V., Ludwig, B., van der Oost, J., Otten, M.F., Oost, J., van der, Westerhoff, H.V.; id_orcid, Reijnders, W.N.M., van Spanning, R.J.M.   +8 more
core   +1 more source

6-PPD quinone at environmentally relevant concentrations activates feedback response of electron transport chain to mediate damage on mitochondrial function and longevity in Caenorhabditis elegans

Environmental Chemistry and Ecotoxicology
6-PPD quinone (6-PPDQ) could cause mitochondrial dysfunction; however, response of entire electron transport chain to 6-PPDQ remains largely unclear. In Caenorhabditis elegans, activity of mitochondrial complex IV was inhibited by 6-PPDQ (1–10 μg/L), and
Xin Hua, Dayong Wang
doaj   +1 more source

High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal

Molecular Neurodegeneration, 2011
Background The activities of mitochondrial complex III (ubiquinol-cytochrome c reductase, EC 1.10.2.2) and complex IV (cytochrome c oxidase EC 1.9.3.1) are reduced by 30-70% in Huntington's disease and Alzheimer's disease, respectively, and are ...
Kilbride Seán M, Gluchowska Sonia A, Telford Jayne E, O'Sullivan Catherine, Davey Gavin P   +4 more
doaj   +1 more source

Anesthesia-Sepsis-Associated Alterations in Liver Gene Expression Profiles and Mitochondrial Oxidative Phosphorylation Complexes

Frontiers in Medicine, 2020
Background: Hepatic dysfunction plays a major role in adverse outcomes in sepsis. Volatile anesthetic agents may protect against organ dysfunction in the setting of critical illness and infection.
Hari Prasad Osuru, Umadevi Paila, Keita Ikeda, Zhiyi Zuo, Robert H. Thiele   +4 more
doaj   +1 more source

Electron optics in ballistic graphene [PDF]

, 2015
This thesis is centered on the experimental observation of electron-optics phenomena in graphene. In Chapter 2, graphene is introduced and the ability to form p-n junctions, with particular regard to electron optics experiments, is discussed.
Rickhaus, Peter
core   +1 more source

Differential requirements for mitochondrial electron transport chain components in the adult murine liver

eLife, 2022
Mitochondrial electron transport chain (ETC) dysfunction due to mutations in the nuclear or mitochondrial genome is a common cause of metabolic disease in humans and displays striking tissue specificity depending on the affected gene.
Nicholas P Lesner, Xun Wang, Zhenkang Chen, Anderson Frank, Cameron J Menezes, Sara House, Spencer D Shelton, Andrew Lemoff, David G McFadden, Janaka Wansapura, Ralph J DeBerardinis, Prashant Mishra   +11 more
doaj   +1 more source

The outer membrane protein Omp35 affects the reduction of Fe(III), nitrate, and fumarate by Shewanella oneidensis MR-1

BMC Microbiology, 2004
Background Shewanella oneidensis MR-1 uses several electron acceptors to support anaerobic respiration including insoluble species such as iron(III) and manganese(IV) oxides, and soluble species such as nitrate, fumarate, dimethylsulfoxide and many ...
Myers Charles R, Maier Tamara M
doaj   +1 more source

Automated quantitative high-throughput multiplex immunofluorescence pipeline to evaluate OXPHOS defects in formalin-fixed human prostate tissue

Scientific Reports, 2022
Advances in multiplex immunofluorescence (mIF) and digital image analysis has enabled simultaneous assessment of protein defects in electron transport chain components. However, current manual methodology is time consuming and labour intensive. Therefore,
Ashwin Sachdeva, Claire A. Hart, Christopher D. Carey, Amy E. Vincent, Laura C. Greaves, Rakesh Heer, Pedro Oliveira, Michael D. Brown, Noel W. Clarke, Doug M. Turnbull   +9 more
doaj   +1 more source