Results 21 to 30 of about 140,758 (163)
Structural basis of mammalian complex IV inhibition by steroids
bioRxiv, 2022 The mitochondrial electron transport chain maintains the proton motive force that powers ATP synthesis. The energy for this process comes from oxidation of NADH and succinate, with the electrons from this oxidation passed via intermediate carriers to ...
Justin M. Di Trani +6 more
semanticscholar +1 more source
A Biophysical Model of the Mitochondrial Respiratory System and Oxidative Phosphorylation. [PDF]
PLoS Computational Biology, 2005 A computational model for the mitochondrial respiratory chain that appropriately balances mass, charge, and free energy transduction is introduced and analyzed based on a previously published set of data measured on isolated cardiac mitochondria.
Daniel A Beard
doaj +2 more sources
Male and Female Mitochondria Respond Differently after Exercising in Acute Hypoxia
Biomedicines, 2023 The use of hypoxic devices among athletes who train in normobaric hypoxia has become increasingly popular; however, the acute effects on heart and brain metabolism are not yet fully understood.
Ylenia Lai +8 more
doaj +1 more source
Neurobiology of Disease, 2022 INTRODUCTION Mitochondrial defects have been implicated in Parkinson's disease (PD) since complex I poisons were found to cause accelerated parkinsonism in young people in the early 1980s. More evidence of mitochondrial involvement arose when many of the
M. E. O'Hanlon +5 more
semanticscholar +1 more source
Mitochondrion (Amsterdam. Print), 2020 We identified Coxfa4l3, previously called C15orf48 or Nmes1, as a novel accessory protein of Complex IV of the mitochondrial electron transport chain (ETC).
Masahiro Endou +6 more
semanticscholar +1 more source
The role of the electron transport chain in immunity
The FASEB Journal, 2021 The electron transport chain (ETC) couples oxidative phosphorylation (OXPHOS) with ATP synthase to drive the generation of ATP. In immune cells, research surrounding the ETC has drifted away from bioenergetics since the discovery of cytochrome c (Cyt c ...
Maureen Yin, L. O’Neill
semanticscholar +1 more source
Pulmonary Circulation, 2020 Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexes are
Danielle J. McCullough +5 more
doaj +1 more source
Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder
Translational Psychiatry, 2021 Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with unique changes in mitochondrial metabolism, including elevated respiration rates and morphological alterations.
Richard E. Frye +13 more
doaj +1 more source
Mitochondrion (Amsterdam. Print), 2022 Photobiomodulation is a term for using low-power red to near-infrared light to stimulate a variety of positive biological effects. Though the scientific and clinical acceptance of PBM as a therapeutic intervention has increased dramatically in recent ...
Nathaniel J. Pope, M. Denton
semanticscholar +1 more source
Developmental Cell, 2021 Summary In order to combat molecular damage, most cellular proteins undergo rapid turnover. We have previously identified large nuclear protein assemblies that can persist for years in post-mitotic tissues and are subject to age-related decline.
S. Krishna +5 more
semanticscholar +1 more source