Results 11 to 20 of about 628,628 (257)

Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport [PDF]

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2010
Respiratory enzyme complex dysfunction is mechanistically involved in mitochondrial failure leading to neurodegenerative disease, but the pathway is unclear. Here, age-related differences in mitochondrial respiration were measured in both whole and permeabilized neurons from 9-month and 24-month adult rat cortex cultured in common conditions.
Gregory J. Brewer, Torrie T. Jones
openaire   +4 more sources

An essential role for an Fe-S cluster protein in the cytochrome c oxidase complex of Toxoplasma parasites.

PLoS Pathogens, 2023
The mitochondrial electron transport chain (ETC) of apicomplexan parasites differs considerably from the ETC of the animals that these parasites infect, and is the target of numerous anti-parasitic drugs.
Rachel A Leonard, Yuan Tian, Feng Tan, Giel G van Dooren, Jenni A Hayward   +4 more
doaj   +1 more source

Quasiballistic electron transport in cryogenic SiGe HBTs studied using an exact, semi-analytic solution to the Boltzmann equation [PDF]

J. Appl. Phys. 130, 174504 (2021), 2021
Silicon-germanium heterojunction bipolar transistors (HBTs) are of interest as low-noise microwave amplifiers due to their competitive noise performance and low cost relative to III-V devices. The fundamental noise performance limits of HBTs are thus of interest, and several studies report that quasiballistic electron transport across the base is a ...
arxiv   +1 more source

Is impaired energy production a novel insight into the pathogenesis of pyridoxine-dependent epilepsy due to biallelic variants in ALDH7A1?

PLoS ONE, 2021
BackgroundPyridoxine-dependent epilepsy (PDE) is due to biallelic variants in ALDH7A1 (PDE-ALDH7A1). ALDH7A1 encodes α-aminoadipic semialdehyde dehydrogenase in lysine catabolism.
Anastasia Minenkova, Erwin E W Jansen, Jessie Cameron, Rob Barto, Thomas Hurd, Lauren MacNeil, Gajja S Salomons, Saadet Mercimek-Andrews   +7 more
doaj   +1 more source

A Biophysical Model of the Mitochondrial Respiratory System and Oxidative Phosphorylation. [PDF]

PLoS Computational Biology, 2005
A computational model for the mitochondrial respiratory chain that appropriately balances mass, charge, and free energy transduction is introduced and analyzed based on a previously published set of data measured on isolated cardiac mitochondria.
Daniel A Beard
doaj   +2 more sources

Male and Female Mitochondria Respond Differently after Exercising in Acute Hypoxia

Biomedicines, 2023
The use of hypoxic devices among athletes who train in normobaric hypoxia has become increasingly popular; however, the acute effects on heart and brain metabolism are not yet fully understood.
Ylenia Lai, Francesco Loy, Michela Isola, Roberta Noli, Andrea Rinaldi, Carla Lobina, Romina Vargiu, Flaminia Cesare Marincola, Raffaella Isola   +8 more
doaj   +1 more source

ElecTra Code: Full-Band Electronic Transport Properties of Materials [PDF]

, 2022
This paper introduces ElecTra, an open-source code which solves the linearized Boltzmann transport equation in the relaxation time approximation for charge carriers in a full-band electronic structure of arbitrary complexity, including their energy, momentum, and band-index dependence.
arxiv   +1 more source

Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder

Translational Psychiatry, 2021
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with unique changes in mitochondrial metabolism, including elevated respiration rates and morphological alterations.
Richard E. Frye, Loïc Lionnard, Indrapal Singh, Mohammad A. Karim, Hanane Chajra, Mathilde Frechet, Karima Kissa, Victor Racine, Amrit Ammanamanchi, Patrick John McCarty, Leanna Delhey, Marie Tippett, Shannon Rose, Abdel Aouacheria   +13 more
doaj   +1 more source

Endurance exercise training in pulmonary hypertension increases skeletal muscle electron transport chain supercomplex assembly

Pulmonary Circulation, 2020
Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexes are
Danielle J. McCullough, Nouaying Kue, Thomas Mancini, Alexander Vang, Richard T. Clements, Gaurav Choudhary   +5 more
doaj   +1 more source

Statistical process control to monitor use of a web‐based autoplanning tool

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the use of statistical process control (SPC) for quality assurance of an integrated web‐based autoplanning tool, Radiation Planning Assistant (RPA). Methods Automatically generated plans were downloaded and imported into two treatment planning systems (TPSs), RayStation and Eclipse, in which they were recalculated using ...
Hunter Mehrens, Raphael Douglas, Mary Gronberg, Kelly Nealon, Joy Zhang, Laurence Court   +5 more
wiley   +1 more source