Results 21 to 30 of about 419,027 (307)
A Biophysical Model of the Mitochondrial Respiratory System and Oxidative Phosphorylation. [PDF]
PLoS Computational Biology, 2005 A computational model for the mitochondrial respiratory chain that appropriately balances mass, charge, and free energy transduction is introduced and analyzed based on a previously published set of data measured on isolated cardiac mitochondria.
Daniel A Beard
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PLoS ONE, 2021 BackgroundPyridoxine-dependent epilepsy (PDE) is due to biallelic variants in ALDH7A1 (PDE-ALDH7A1). ALDH7A1 encodes α-aminoadipic semialdehyde dehydrogenase in lysine catabolism.
Anastasia Minenkova +7 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 In mammalian cells, cyanide is viewed as a cytotoxic agent, which exerts its effects through inhibition of mitochondrial Complex IV (Cytochrome C oxidase [CCOx]).
Elisa B. Randi +4 more
semanticscholar +1 more source
New Phytologist, 2023 We studied Arabidopsis HYPOXIA-RESPONSIVE MODULATOR 1 (HRM1), which belongs to a group of core hypoxia-responsive genes that are conserved among plant species across great evolutionary distance.
K.-J. Tsai, D. Suen, M. Shih
semanticscholar +1 more source
The role of the electron transport chain in immunity
The FASEB Journal, 2021 The electron transport chain (ETC) couples oxidative phosphorylation (OXPHOS) with ATP synthase to drive the generation of ATP. In immune cells, research surrounding the ETC has drifted away from bioenergetics since the discovery of cytochrome c (Cyt c ...
Maureen Yin, L. O’Neill
semanticscholar +1 more source
Male and Female Mitochondria Respond Differently after Exercising in Acute Hypoxia
Biomedicines, 2023 The use of hypoxic devices among athletes who train in normobaric hypoxia has become increasingly popular; however, the acute effects on heart and brain metabolism are not yet fully understood.
Ylenia Lai +8 more
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Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder
Translational Psychiatry, 2021 Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with unique changes in mitochondrial metabolism, including elevated respiration rates and morphological alterations.
Richard E. Frye +13 more
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Regulation and functional role of the electron transport chain supercomplexes
Biochemical Society Transactions, 2021 Mitochondria are one of the most exhaustively investigated organelles in the cell and most attention has been paid to the components of the mitochondrial electron transport chain (ETC) in the last 100 years.
S. Cogliati +2 more
semanticscholar +1 more source
A Structural Model of the Cytochrome c Reductase/Oxidase Supercomplex from Yeast Mitochondria [PDF]
, 2007 Mitochondrial respiratory chain complexes are arranged in supercomplexes within the inner membrane. Interaction of cytochrome c reductase (complex III) and cytochrome c oxidase (complex IV) was investigated in Saccharomyces cerevisiae. Projection maps at
Allen +43 more
core +4 more sources
Pulmonary Circulation, 2020 Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexes are
Danielle J. McCullough +5 more
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