Results 21 to 30 of about 110,844 (170)

A Biophysical Model of the Mitochondrial Respiratory System and Oxidative Phosphorylation. [PDF]

open access: yesPLoS Computational Biology, 2005
A computational model for the mitochondrial respiratory chain that appropriately balances mass, charge, and free energy transduction is introduced and analyzed based on a previously published set of data measured on isolated cardiac mitochondria.
Daniel A Beard
doaj   +2 more sources

Hypoxia response protein HRM1 modulates the activity of mitochondrial electron transport chain in Arabidopsis under hypoxic stress.

open access: yesNew Phytologist, 2023
We studied Arabidopsis HYPOXIA-RESPONSIVE MODULATOR 1 (HRM1), which belongs to a group of core hypoxia-responsive genes that are conserved among plant species across great evolutionary distance.
K.-J. Tsai, D. Suen, M. Shih
semanticscholar   +1 more source

Male and Female Mitochondria Respond Differently after Exercising in Acute Hypoxia

open access: yesBiomedicines, 2023
The use of hypoxic devices among athletes who train in normobaric hypoxia has become increasingly popular; however, the acute effects on heart and brain metabolism are not yet fully understood.
Ylenia Lai   +8 more
doaj   +1 more source

The role of the electron transport chain in immunity

open access: yesThe FASEB Journal, 2021
The electron transport chain (ETC) couples oxidative phosphorylation (OXPHOS) with ATP synthase to drive the generation of ATP. In immune cells, research surrounding the ETC has drifted away from bioenergetics since the discovery of cytochrome c (Cyt c ...
Maureen Yin, L. O’Neill
semanticscholar   +1 more source

Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder

open access: yesTranslational Psychiatry, 2021
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with unique changes in mitochondrial metabolism, including elevated respiration rates and morphological alterations.
Richard E. Frye   +13 more
doaj   +1 more source

Regulation and functional role of the electron transport chain supercomplexes

open access: yesBiochemical Society Transactions, 2021
Mitochondria are one of the most exhaustively investigated organelles in the cell and most attention has been paid to the components of the mitochondrial electron transport chain (ETC) in the last 100 years.
S. Cogliati   +2 more
semanticscholar   +1 more source

Endurance exercise training in pulmonary hypertension increases skeletal muscle electron transport chain supercomplex assembly

open access: yesPulmonary Circulation, 2020
Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexes are
Danielle J. McCullough   +5 more
doaj   +1 more source

Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis

open access: yeseLife, 2021
While transcripts of neuronal mitochondrial genes are strongly suppressed in central nervous system inflammation, it is unknown whether this results in mitochondrial dysfunction and whether an increase of mitochondrial function can rescue ...
Sina C Rosenkranz   +16 more
doaj   +1 more source

Tissue-specific mitochondrial HIGD1C promotes oxygen sensitivity in carotid body chemoreceptors

open access: yeseLife, 2022
Mammalian carotid body arterial chemoreceptors function as an early warning system for hypoxia, triggering acute life-saving arousal and cardiorespiratory reflexes. To serve this role, carotid body glomus cells are highly sensitive to decreases in oxygen
Alba Timón-Gómez   +16 more
doaj   +1 more source

Respiratory electron transfer pathways in plant mitochondria

open access: yesFrontiers in Plant Science, 2014
The respiratory electron transport chain (ETC) couples electron transfer from organic substrates onto molecular oxygen with proton translocation across the inner mitochondrial membrane.
Peter eSchertl, Hans-Peter eBraun
doaj   +1 more source

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