Results 31 to 40 of about 628,628 (257)

High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal

open access: yesMolecular Neurodegeneration, 2011
Background The activities of mitochondrial complex III (ubiquinol-cytochrome c reductase, EC 1.10.2.2) and complex IV (cytochrome c oxidase EC 1.9.3.1) are reduced by 30-70% in Huntington's disease and Alzheimer's disease, respectively, and are ...
Kilbride Seán M   +4 more
doaj   +1 more source

Anesthesia-Sepsis-Associated Alterations in Liver Gene Expression Profiles and Mitochondrial Oxidative Phosphorylation Complexes

open access: yesFrontiers in Medicine, 2020
Background: Hepatic dysfunction plays a major role in adverse outcomes in sepsis. Volatile anesthetic agents may protect against organ dysfunction in the setting of critical illness and infection.
Hari Prasad Osuru   +4 more
doaj   +1 more source

Differential requirements for mitochondrial electron transport chain components in the adult murine liver

open access: yeseLife, 2022
Mitochondrial electron transport chain (ETC) dysfunction due to mutations in the nuclear or mitochondrial genome is a common cause of metabolic disease in humans and displays striking tissue specificity depending on the affected gene.
Nicholas P Lesner   +11 more
doaj   +1 more source

Biological free energy transduction is an Achilles heel of mean-field transport theory [PDF]

open access: yesarXiv, 2022
Studies of nanoscale biological transport often use a mean-field approximation that is exact only when the system is at equilibrium and there are no interactions between particles on different sites in the network. We explore the limitations of this approximation to describe many-particle transport in the context of enzyme function and biological ...
arxiv  

Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView., 2023
Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal   +5 more
wiley   +1 more source

Structural studies of T4S systems by electron microscopy

open access: yesAIMS Biophysics, 2015
Type IV secretion (T4S) systems are large dynamic nanomachines that transport DNA and/or proteins through the membranes of bacteria. Analysis of T4S system architecture is an extremely challenging task taking into account their multi protein organisation
Adam Redzej   +2 more
doaj   +1 more source

Driving current through single organic molecules [PDF]

open access: yesPhys. Rev. Lett. 88, 176804 (2002), 2001
We investigate electronic transport through two types of conjugated molecules. Mechanically controlled break-junctions are used to couple thiol endgroups of single molecules to two gold electrodes. Current-voltage characteristics (IVs) of the metal-molecule-metal system are observed.
arxiv   +1 more source

Automated quantitative high-throughput multiplex immunofluorescence pipeline to evaluate OXPHOS defects in formalin-fixed human prostate tissue

open access: yesScientific Reports, 2022
Advances in multiplex immunofluorescence (mIF) and digital image analysis has enabled simultaneous assessment of protein defects in electron transport chain components. However, current manual methodology is time consuming and labour intensive. Therefore,
Ashwin Sachdeva   +9 more
doaj   +1 more source

Charge transport modulation by a redox supramolecular spin-filtering chiral crystal [PDF]

open access: yesarXiv, 2023
The chirality induced spin selectivity (CISS) effect is a fascinating phenomena correlating molecular structure with electron spin-polarisation in excited state measurements. Experimental procedures to quantify the spin-filtering magnitude relies generally on averaging data sets, especially those from magnetic field dependent conductive-AFM.
arxiv  

Current facilitation by plasmon resonances between parallel wires of finite length [PDF]

open access: yesEurophys. Lett. 62, 561 (2003), 2002
The current voltage (IV) characteristics for perpendicular transport through two sequentially coupled wires of finite length is calculated analytically. The transport within a Coulomb blockade step is assisted by plasmon resonances that appear as steps in the IV characteristics with positions and heights depending on inter- and intrawire interactions ...
arxiv   +1 more source

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