Results 31 to 40 of about 95,409 (213)

Glutathione binding to the plant AtAtm3 transporter and implications for the conformational coupling of ABC transporters

eLife, 2022
The ATP binding cassette (ABC) transporter of mitochondria (Atm) from Arabidopsis thaliana (AtAtm3) has been implicated in the maturation of cytosolic iron-sulfur proteins and heavy metal detoxification, plausibly by exporting glutathione derivatives ...
Chengcheng Fan, Douglas C Rees
doaj   +1 more source

Brownian dynamics simulation of cytochrome c diffusion and binding with cytochrome c1 in mitochondrial crista [PDF]

ITM Web of Conferences, 2020
Cytochrome c (Cc) protein shuttles electrons from respiratory chain complex III — from cytochrome c1 (Cc1) subunit — to complex IV during oxidative phosphorylation, in intermembrane space of mitochondria and cristae lumen.
Abaturova Anna M., Brazhe Nadezda A., Kovalenko Ilya B., Riznichenko Galina Yu, Rubin Andrei B.   +4 more
doaj   +1 more source

Near-infrared 808 nm light boosts complex IV-dependent respiration and rescues a Parkinson-related pink1 model. [PDF]

PLoS ONE, 2013
Mitochondrial electron transport chain (ETC) defects are observed in Parkinson's disease (PD) patients and in PD fly- and mouse-models; however it remains to be tested if acute improvement of ETC function alleviates PD-relevant defects.
Melissa Vos, Blaise Lovisa, Ann Geens, Vanessa A Morais, Georges Wagnières, Hubert van den Bergh, Alec Ginggen, Bart De Strooper, Yanik Tardy, Patrik Verstreken   +9 more
doaj   +1 more source

Sordaria macrospora Sterile Mutant pro34 Is Impaired in Respiratory Complex I Assembly

Journal of Fungi, 2022
The formation of fruiting bodies is a highly regulated process that requires the coordinated formation of different cell types. By analyzing developmental mutants, many developmental factors have already been identified.
Andrea Hamann, Heinz D. Osiewacz, Ines Teichert   +2 more
doaj   +1 more source

Hyperoxia decreases glycolytic capacity, glycolytic reserve and oxidative phosphorylation in MLE-12 cells and inhibits complex I and II function, but not complex IV in isolated mouse lung mitochondria.

PLoS ONE, 2013
High levels of oxygen (hyperoxia) are frequently used in critical care units and in conditions of respiratory insufficiencies in adults, as well as in infants.
Kumuda C Das
doaj   +1 more source

Anesthesia-Sepsis-Associated Alterations in Liver Gene Expression Profiles and Mitochondrial Oxidative Phosphorylation Complexes

Frontiers in Medicine, 2020
Background: Hepatic dysfunction plays a major role in adverse outcomes in sepsis. Volatile anesthetic agents may protect against organ dysfunction in the setting of critical illness and infection.
Hari Prasad Osuru, Umadevi Paila, Keita Ikeda, Zhiyi Zuo, Robert H. Thiele   +4 more
doaj   +1 more source

High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal

Molecular Neurodegeneration, 2011
Background The activities of mitochondrial complex III (ubiquinol-cytochrome c reductase, EC 1.10.2.2) and complex IV (cytochrome c oxidase EC 1.9.3.1) are reduced by 30-70% in Huntington's disease and Alzheimer's disease, respectively, and are ...
Kilbride Seán M, Gluchowska Sonia A, Telford Jayne E, O'Sullivan Catherine, Davey Gavin P   +4 more
doaj   +1 more source

Differential requirements for mitochondrial electron transport chain components in the adult murine liver

eLife, 2022
Mitochondrial electron transport chain (ETC) dysfunction due to mutations in the nuclear or mitochondrial genome is a common cause of metabolic disease in humans and displays striking tissue specificity depending on the affected gene.
Nicholas P Lesner, Xun Wang, Zhenkang Chen, Anderson Frank, Cameron J Menezes, Sara House, Spencer D Shelton, Andrew Lemoff, David G McFadden, Janaka Wansapura, Ralph J DeBerardinis, Prashant Mishra   +11 more
doaj   +1 more source

Structural studies of T4S systems by electron microscopy

AIMS Biophysics, 2015
Type IV secretion (T4S) systems are large dynamic nanomachines that transport DNA and/or proteins through the membranes of bacteria. Analysis of T4S system architecture is an extremely challenging task taking into account their multi protein organisation
Adam Redzej, Gabriel Waksman, Elena V Orlova   +2 more
doaj   +1 more source

6-PPD quinone at environmentally relevant concentrations activates feedback response of electron transport chain to mediate damage on mitochondrial function and longevity in Caenorhabditis elegans

Environmental Chemistry and Ecotoxicology
6-PPD quinone (6-PPDQ) could cause mitochondrial dysfunction; however, response of entire electron transport chain to 6-PPDQ remains largely unclear. In Caenorhabditis elegans, activity of mitochondrial complex IV was inhibited by 6-PPDQ (1–10 μg/L), and
Xin Hua, Dayong Wang
doaj   +1 more source