Results 41 to 50 of about 142 (64)

Different Effects of SSRIs, Bupropion, and Trazodone on Mitochondrial Functions and Monoamine Oxidase Isoform Activity

Antioxidants, 2023
Mitochondrial dysfunction is involved in the pathophysiology of psychiatric and neurodegenerative disorders and can be used as a modulator and/or predictor of treatment responsiveness.
Matej Ľupták, Zdeněk Fišar, Jana Hroudová   +2 more
doaj   +1 more source

Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex.

PLoS Pathogens, 2021
The mitochondrial electron transport chain (mETC) and F1Fo-ATP synthase are of central importance for energy and metabolism in eukaryotic cells. The Apicomplexa, important pathogens of humans causing diseases such as toxoplasmosis and malaria, depend on ...
Andrew E Maclean, Hannah R Bridges, Mariana F Silva, Shujing Ding, Jana Ovciarikova, Judy Hirst, Lilach Sheiner   +6 more
doaj   +1 more source

Euglena’s atypical respiratory chain adapts to the discoidal cristae and flexible metabolism

Nature Communications
Euglena gracilis, a model organism of the eukaryotic supergroup Discoba harbouring also clinically important parasitic species, possesses diverse metabolic strategies and an atypical electron transport chain.
Zhaoxiang He, Mengchen Wu, Hongtao Tian, Liangdong Wang, Yiqi Hu, Fangzhu Han, Jiancang Zhou, Yong Wang, Long Zhou   +8 more
doaj   +1 more source

Unique, Diverged, and Conserved Mitochondrial Functions Influencing Candida albicans Respiration

mBio, 2019
Candida albicans is an opportunistic fungal pathogen of major clinical concern. The virulence of this pathogen is intimately intertwined with its metabolism.
Nuo Sun, Rebecca S. Parrish, Richard A. Calderone, William A. Fonzi   +3 more
doaj   +1 more source

Adapting High-Resolution Respirometry to Glucose-Limited Steady State Mycelium of the Filamentous Fungus Penicillium ochrochloron: Method Development and Standardisation.

PLoS ONE, 2016
Fungal electron transport systems (ETS) are branched, involving alternative NADH dehydrogenases and an alternative terminal oxidase. These alternative respiratory enzymes were reported to play a role in pathogenesis, production of antibiotics and ...
Christoph W Schinagl, Pamela Vrabl, Wolfgang Burgstaller   +2 more
doaj   +1 more source

COX4I1 Controls Mitochondrial Electron Transport Chain Complex IV Assembly and Leukemia Progression in Acute Myeloid Leukemia

, 2023
Leisi Zhang, Mingli Li, Anthony K. N. Chan, Qiao Liu, HyunJun Kang, Sheela Pangeni Pokharel, Nicole Mattson, Priyanka Singh, Lu Yang, Chun–Wei Chen   +9 more
openalex   +1 more source

Ascorbate Biosynthesis in Mitochondria Is Linked to the Electron Transport Chain between Complexes III and IV [PDF]

, 2000
Carlos G. Bartoli, G. M. Pastori, Christine H. Foyer   +2 more
openalex   +1 more source

Mitochondrial dysfunction in brain tissues and Extracellular Vesicles Fragile X‐associated tremor/ataxia syndrome

Annals of Clinical and Translational Neurology
Objective Mitochondrial impairments have been implicated in the pathogenesis of Fragile X‐associated tremor/ataxia syndrome (FXTAS) based on analysis of mitochondria in peripheral tissues and cultured cells.
Pamela J. Yao, Apostolos Manolopoulos, Erden Eren, Susan Michelle Rivera, David R. Hessl, Randi Hagerman, Veronica Martinez‐Cerdeno, Flora Tassone, Dimitrios Kapogiannis   +8 more
doaj   +1 more source

Age-related deficiencies in complex I endogenous substrate availability and reserve capacity of complex IV in cortical neuron electron transport [PDF]

, 2009
Torrie T. Jones, Gregory J. Brewer
openalex   +1 more source

Sodium fluoride causes oxidative damage to silkworm (Bombyx mori) testis by affecting the oxidative phosphorylation pathway

Ecotoxicology and Environmental Safety, 2021
Bombyx mori was used to study the molecular mechanism of fluoride induced reproductive toxicity. In our previous study, we confirmed the physiological and biochemical effects of NaF on reproductive toxicity, and we found that the molecular mechanism of ...
Wenchao Tang, Yuanyuan Xiao, Yaohang Long, Yaofeng Li, Fang Peng, Can Zhu, Tinggui He, Didong Lou, Yong Zhu   +8 more
doaj