Results 131 to 140 of about 127,262 (303)
Cardiac Ablation by Electroporation
JACC: Clinical Electrophysiology, 2018 In a recent State-of-the-Art Review article, Wittkampf et al. [(1)][1] offered their view on irreversible electroporation (IRE) as a promising and potentially disruptive technology in cardiac ablation for pulmonary vein isolation.
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Dielectric Elastomer Actuators as Safe and Effective Tools for Mechanostimulation of Human Cells
Advanced Intelligent Systems, EarlyView.Replicating physiological forces is crucial for realistic cell models. Dielectric elastomer actuators (DEAs) offer a soft alternative, though their high voltages raised toxicity concerns. We demonstrate that DEA stimulation causes no cell damage, cell death or cell‐cycle disruption, while activating mechanosensitive responses.
Simon Holzer +6 more
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626 Improving the yeast transformation efficiency for yeast display in antibody development
Journal for ImmunoTherapy of Cancer, 2020 Jian Chen, George Sun
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Development of immunocompetent models for primary and metastatic ER+ breast cancer
Animal Models and Experimental Medicine, EarlyView.This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull +5 more
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535 Electroporation of B cells is correlated with cell size change during B cell expansion
Journal for ImmunoTherapy of Cancer, 2020 Jian Chen, George Sun
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MicromachinesIn situ electroporation, a non-invasive technique for enhancing the permeability of cell membranes, has emerged as a powerful tool for intracellular delivery and manipulation. This method allows for the precise introduction of therapeutic agents, such as
Haizhen Sun +4 more
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Irreversible Electroporation in Medicine
Technology in Cancer Research & Treatment, 2007 This is a brief introduction to the emerging field of irreversible electroporation in medicine. Certain electrical fields when applied across a cell can have as a sole effect the permeabilization of the cell membrane, presumable through the formation of nanoscale defects in the cell membrane.
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Incorporation of the blood vessel wall into electroporation simulations
, 2015 Electroporation can be used in living tissues in order to enhance the penetration of drugs or DNA plasmids or to destroy undesirable cells and it is typically performed by applying pulsed high voltages across needle electrodes. When used for ablation, it
Qasrawi, Radwan Fayez Hasan +2 more
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Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source