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International Journal of Molecular Sciences, 2022 Most diploid freshwater and marine fish encode one elovl5 elongase, having substrate specificity and activities towards C18, C20 and C22 polyunsaturated fatty acids (PUFAs).
Shang qi Li, Jiong-Tang Li, Yan Zhang
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Plant Molecular Biology, 2008 As precursors of wax compounds, very long chain fatty acids participate in the limitation of non-stomatal water loss and the prevention of pathogen attacks. They also serve as energy storage in seeds and as membrane building blocks. Their biosynthesis is
Jérôme Joubès +2 more
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Fatty acid elongases in mammals: Their regulation and roles in metabolism
Progress in Lipid Research, 2006A significant amount of the fatty acids synthesized by the cytosolic enzyme complex fatty acid synthase (FAS) or taken up by the diet are further elongated into very long chain fatty acids (VLCFA) in a four-step reaction cycle by membrane-bound enzymes predominantly located in the endoplasmic reticulum.
Andreas, Jakobsson +2 more
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Identification and characterization of two fatty acid elongases in Lipomyces starkeyi
Applied Microbiology and Biotechnology, 2020The oleaginous yeast Lipomyces starkeyi is a potential cost-effective source for the production of microbial lipids. Fatty acid elongases have vital roles in the syntheses of long-chain fatty acids. In this study, two genes encoding fatty acid elongases of L. starkeyi, LsELO1, and LsELO2 were identified and characterized.
Tomohiko Matsuzawa +4 more
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Partial purification of the Acyl-CoA elongase of Allium porrum leaves
Archives of Biochemistry and Biophysics, 1989Acyl-CoA elongase has been partially purified from leek (Allium porrum L.) epidermal cells. The microsomal elongase is first solubilized by Triton X-100. The solubilized proteins are then submitted to anion exchange chromatography on DEAE-cellulose and, finally, to gel filtration on Ultrogel 34 AcA.
J J, Bessoule, R, Lessire, C, Cassagne
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Distinct developmental expression of two elongase family members in zebrafish
Biochemical and Biophysical Research Communications, 2010Despite the known importance of long-chained polyunsaturated fatty acids (LC-PUFA) during development, very little is known about their utilization and biosynthesis during embryogenesis. Combining the advantages of the existence of a complete range of enzymes required for LC-PUFA biosynthesis and the well established developmental biology tools in ...
Sze-Huey, Tan +2 more
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A new elongase selectively expressed in Drosophila male reproductive system
Biochemical and Biophysical Research Communications, 2005We have identified an elongase gene, elo68alpha, which is specifically transcribed in males. We have characterized the elo68alpha open reading frame, expressed it in fasDelta elo1Delta yeast and showed that it could elongate myristoleic and palmitoleic acids, therefore sharing an Elo1 specificity.
Thomas, Chertemps +3 more
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3D Structure Modeling of a Transmembrane Protein, Fatty Acid Elongase
2010Fatty acid elongase is an enzyme responsible for fatty acid chain elongation, a key step in synthesis of long chain fatty acids, including polyunsaturated fatty acids (PUFAs). Currently, the increasing demand has raised the interest in obtaining these PUFAs from alternative sources, e.g. filamentous fungi that are more economical and sustainable.
Sansai Chumningan +4 more
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RT-PCR OF FATTY ACID ELONGASES
Biochemical Society Transactions, 1997A P, Kells, P V, Maynard
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