Results 171 to 180 of about 8,091 (214)
One-carbon-derived bioactive peptides improve reproductive performance via regulating placental nutrient transport and offspring glycolipid metabolism. [PDF]
Gao LM +6 more
europepmc +1 more source
Meldonium-induced steatosis is associated with increased delta 6 desaturation and reduced elongation of n-6 polyunsaturated fatty acids. [PDF]
Bjørndal B +6 more
europepmc +1 more source
Most diploid freshwater and marine fish encode one elovl5 elongase, having substrate specificity and activities towards C18, C20 and C22 polyunsaturated fatty acids (PUFAs).
Ran Zhao, Shang-Qi Li, Xiao-Qing Sun
exaly +2 more sources
As precursors of wax compounds, very long chain fatty acids participate in the limitation of non-stomatal water loss and the prevention of pathogen attacks. They also serve as energy storage in seeds and as membrane building blocks. Their biosynthesis is
Jérôme Joubès +2 more
exaly +2 more sources
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A new elongase selectively expressed in Drosophila male reproductive system
Biochemical and Biophysical Research Communications, 2005We have identified an elongase gene, elo68alpha, which is specifically transcribed in males. We have characterized the elo68alpha open reading frame, expressed it in fasDelta elo1Delta yeast and showed that it could elongate myristoleic and palmitoleic acids, therefore sharing an Elo1 specificity.
Claude Wicker-Thomas
exaly +3 more sources
Marine Biotechnology, 2013
Thraustochytrids, unicellular eukaryotic marine protists, accumulate polyunsaturated fatty acids. Here, we report the molecular cloning and functional characterization of two fatty acid elongase genes (designated tselo1 and tselo2), which could be involved in the desaturase/elongase (standard) pathway in Thraustochytrium sp. ATCC 26185.
Keishi Sakaguchi +2 more
exaly +3 more sources
Thraustochytrids, unicellular eukaryotic marine protists, accumulate polyunsaturated fatty acids. Here, we report the molecular cloning and functional characterization of two fatty acid elongase genes (designated tselo1 and tselo2), which could be involved in the desaturase/elongase (standard) pathway in Thraustochytrium sp. ATCC 26185.
Keishi Sakaguchi +2 more
exaly +3 more sources
Fatty acid elongases in mammals: Their regulation and roles in metabolism
Progress in Lipid Research, 2006A significant amount of the fatty acids synthesized by the cytosolic enzyme complex fatty acid synthase (FAS) or taken up by the diet are further elongated into very long chain fatty acids (VLCFA) in a four-step reaction cycle by membrane-bound enzymes predominantly located in the endoplasmic reticulum.
Andreas, Jakobsson +2 more
openaire +2 more sources
Identification and characterization of two fatty acid elongases in Lipomyces starkeyi
Applied Microbiology and Biotechnology, 2020The oleaginous yeast Lipomyces starkeyi is a potential cost-effective source for the production of microbial lipids. Fatty acid elongases have vital roles in the syntheses of long-chain fatty acids. In this study, two genes encoding fatty acid elongases of L. starkeyi, LsELO1, and LsELO2 were identified and characterized.
Tomohiko Matsuzawa +4 more
openaire +2 more sources
Biosynthesis of long-chain polyunsaturated fatty acids in marine fish: Characterization of an Elovl4-like elongase from cobia Rachycentron canadum and activation of the pathway during early life stages [PDF]
Marine fish, unlike freshwater species, have been generally considered to have a limited ability to biosynthesize long-chain polyunsaturated fatty acids (LC-PUFA) from C18 precursors due to apparent limited enzymatic activities involved in the pathway ...
OSCAR Monroig +2 more
exaly +2 more sources

