Results 61 to 70 of about 143,897 (248)
Advanced Science, EarlyView.CircPROSC promotes craniosynostosis by sponging miR‐6815‐5p, thereby activating WNT3A/β‐catenin signaling and enhancing RUNX2‐mediated osteogenesis. Targeted silencing of circPROSC with MSC membrane–coated siRNA nanoparticles (MM@Lipo/si‐circPROSC) delivered postnatally into cranial sutures attenuates premature suture closure in Twist1+/– mice ...
Zhenkun Weng +6 more
wiley +1 more source
Partial synchronization of the colonial diatom Bacillaria "paradoxa" [PDF]
Research Ideas and Outcomes, 2016 Richard Gordon
doaj +2 more sources
Using Morphogenic Genes to Improve Recovery and Regeneration of Transgenic Plants
Plants, 2019 Efficient transformation of numerous important crops remains a challenge, due predominantly to our inability to stimulate growth of transgenic cells capable of producing plants.
Bill Gordon-Kamm +6 more
doaj +1 more source
Stress responses and epigenomic instability mark the loss of somatic embryogenesis competence in grapevine [PDF]
, 2021 Silvia Dal Santo +8 more
openalex +1 more source
Molecular Insights into Fungal Glycosylphosphatidylinositol Transamidase Complex
Advanced Science, EarlyView.The glycosylphosphatidylinositol (GPI) biosynthesis pathway is critical for antifungal drug development. This study reports three cryo‐electron microscopy structures of fungal GPI transamidase (GPIT), captured in two substrate‐bound states and a novel dimeric assembly.
Zhengkang Hua +12 more
wiley +1 more source
Cuttlefish Early Development and Behavior Under Future High CO2 Conditions
Frontiers in Physiology, 2019 The oceanic uptake of carbon dioxide (CO2) is increasing and changing the seawater chemistry, a phenomenon known as ocean acidification (OA). Besides the expected physiological impairments, there is an increasing evidence of detrimental OA effects on the
Érica Moura +8 more
doaj +1 more source
Frontiers in Marine Science, 2020 The Intergovernmental Panel on Climate Change (IPCC) predicted that ocean surface temperature will rise of 0.6–2.0°C by 2100. Ocean warming is expected to produce strong impacts on marine ecosystems such as coral reefs, affecting their physiological ...
Chiara Marchini +7 more
doaj +1 more source
Advanced Science, EarlyView.Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan +19 more
wiley +1 more source
Frontiers in Molecular Neuroscience, 2019 In the developing organism, complex molecular programs orchestrate the generation of cells in adequate numbers, drive them to migrate along the correct pathways towards appropriate territories, eliminate superfluous cells, and induce terminal ...
Céline Delloye-Bourgeois +1 more
doaj +1 more source
Advanced Science, EarlyView.A dynamic granular system composed of microgels crosslinked through guest‐host interactions is developed to reversibly alter its stiffness and microporosity in response to chemical stimuli, enabling temporal regulation of cell migration. Suspension bioprinting using this dynamic hydrogel allows for 4D spatiotemporal control over tissue formation ...
Keisuke Nakamura +4 more
wiley +1 more source