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Retinoids in Embryonic Development [PDF]

Biomolecules, 2020
Retinoids constitute a class of compounds chemically related to vitamin A [...]
Michael Schubert, Yann Gibert
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Programming of Embryonic Development [PDF]

International Journal of Molecular Sciences, 2021
Assisted reproductive techniques (ART) and parental nutritional status have profound effects on embryonic/fetal and placental development, which are probably mediated via “programming” of gene expression, as reflected by changes in their epigenetic landscape. Such epigenetic changes may underlie programming of growth, development, and function of fetal
Carl R. Dahlen, Pawel P. Borowicz, Alison K. Ward, Joel S. Caton, Marta Czernik, Luca Palazzese, Pasqualino Loi, Lawrence P. Reynolds   +7 more
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NF-κB activation impedes the transdifferentiation of hypertrophic chondrocytes at the growth plate of mouse embryos in diabetic pregnancy

Journal of Orthopaedic Translation, 2021
Background: Diabetes mellitus could cause numerous complications and health problems including abnormality of endochondral bone formation during embryogenesis. However, the underlying mechanisms still remain obscure.
Xi Liu, Fan Qian, Qiwei Fan, Li Lin, Meiyao He, Peizhi Li, Hongmei Cai, Lisha Ma, Xin Cheng, Xuesong Yang   +9 more
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CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion

Frontiers in Immunology, 2021
Recurrent spontaneous abortion (RSA) affects 5% of childbearing-age women worldwide. Inadequate trophoblast invasion is one of the main reasons for the development of RSA; however, the underlying molecular mechanisms for RSA have not been fully ...
Sainan Zhang, Jinli Ding, Jiayu Wang, Tailang Yin, Yan Zhang, Jing Yang   +5 more
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Waves in Embryonic Development

Annual Review of Biophysics, 2022
Embryonic development hinges on effective coordination of molecular events across space and time. Waves have recently emerged as constituting an ubiquitous mechanism that ensures rapid spreading of regulatory signals across embryos, as well as reliable control of their patterning, namely, for the emergence of body plan structures.
Di Talia, Stefano, Vergassola, Massimo
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Reconstructing embryonic development [PDF]

genesis, 2011
AbstractNovel approaches to bio‐imaging and automated computational image processing allow the design of truly quantitative studies in developmental biology. Cell behavior, cell fate decisions, cell interactions during tissue morphogenesis, and gene expression dynamics can be analyzed in vivo for entire complex organisms and throughout embryonic ...
Khaled, Khairy, Philipp J, Keller
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USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN

Frontiers in Cell and Developmental Biology, 2021
Background: Polycystic ovarian syndrome (PCOS) is an endocrine-related disease related to abnormal folliculogenesis and is a leading cause of infertility worldwide.
Yue Gao, Jiao Chen, Rui Ji, Jinli Ding, Yan Zhang, Jing Yang   +5 more
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Mitochondrial contributions to oocyte and embryonic quality in bovine [PDF]

SPERMOVA, 2017
Mitochondria are powerhouse organelles involved in several vital functions in cells, mainly maintaining balance between ATP synthesis and oxidative stress during early development in mammalian embryos.
Baldoceda L, Robert C
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Retinoic Acid Signaling Plays a Crucial Role in Excessive Caffeine Intake-Disturbed Apoptosis and Differentiation of Myogenic Progenitors

Frontiers in Cell and Developmental Biology, 2021
Whether or not the process of somitogenesis and myogenesis is affected by excessive caffeine intake still remains ambiguous. In this study, we first showed that caffeine treatment results in chest wall deformities and simultaneously reduced mRNA ...
Nian Wu, Nian Wu, Yingshi Li, Xiangyue He, Xiangyue He, Jiayi Lin, Denglu Long, Xin Cheng, Beate Brand-Saberi, Guang Wang, Guang Wang, Xuesong Yang, Xuesong Yang   +12 more
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Non-Coding RNAs Regulate Placental Trophoblast Function and Participate in Recurrent Abortion

Frontiers in Pharmacology, 2021
Recurrent spontaneous abortion (RSA) is a serious pregnancy complication with an increasing clinical incidence. The various causes of recurrent abortion are complicated.
Xin Chen, Duan-Ying Guo, Tai-Lang Yin, Jing Yang   +3 more
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