Results 11 to 20 of about 15,439,652 (357)

Maternal and infant outcomes during the COVID-19 pandemic: a retrospective study in Guangzhou, China

Reproductive Biology and Endocrinology, 2021
In late December 2019, the COVID-19 pandemic caused a great threat to people’s lives worldwide. As a special category of the population, pregnant women are vulnerable during emergencies.
Jingyun Wang, Yun Wang, Mei-yao He, Yi-xiao Li, Xin Cheng, Xuesong Yang, Rui-man Li, Guang Wang   +7 more
doaj   +1 more source

Regulation and Function of Chemokines at the Maternal–Fetal Interface

Frontiers in Cell and Developmental Biology, 2022
Successful pregnancy requires the maternal immune system to tolerate the semi-allogeneic embryo. A good trophoblast function is also essential for successful embryo implantation and subsequent placental development.
Sainan Zhang, Jinli Ding, Yan Zhang, Su Liu, Jing Yang, Tailang Yin   +5 more
doaj   +1 more source

The Conceivable Functions of Protein Ubiquitination and Deubiquitination in Reproduction

Frontiers in Physiology, 2022
Protein ubiquitination with general existence in virtually all eukaryotic cells serves as a significant post-translational modification of cellular proteins, which leads to the degradation of proteins via the ubiquitin–proteasome system. Deubiquitinating
Jiayu Wang, Jiayu Wang, Qi Zhou, Qi Zhou, Jinli Ding, Jinli Ding, Tailang Yin, Tailang Yin, Peng Ye, Yan Zhang, Yan Zhang   +10 more
doaj   +1 more source

Mechano-biochemical marine stimulation of inversion, gastrulation, and endomesoderm specification in multicellular Eukaryota

Frontiers in Cell and Developmental Biology, 2022
The evolutionary emergence of the primitive gut in Metazoa is one of the decisive events that conditioned the major evolutionary transition, leading to the origin of animal development.
Ngoc Minh Nguyen, Tatiana Merle, Florence Broders-Bondon, Anne-Christine Brunet, Aude Battistella, Emelie Britt Linnea Land, Florian Sarron, Aditya Jha, Jean-Luc Gennisson, Eric Röttinger, Eric Röttinger, María Elena Fernández-Sánchez, Emmanuel Farge   +12 more
doaj   +1 more source

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors. [PDF]

, 2015
The genomic regulatory programmes that underlie human organogenesis are poorly understood. Pancreas development, in particular, has pivotal implications for pancreatic regeneration, cancer and diabetes.
A Kapoor, A Krapp, A Rada-Iglesias, A Sawada, A-C Binot, AF Hezel, AJ Saldanha, B Zhao, B Zhao, C Cortijo, C Haumaitre, C Trapnell, CHH Cho, CY McLean, DA Stoffers, DW Huang, E Kroon, E Rodríguez-Seguel, EF Chiang, F Argenton, F Esni, F Supek, FC Lynn, FC Pan, H Fang, H Fang, H Lango Allen, I Morán, I Rooman, J Bessa, J van Arensbergen, JM Oliver-Krasinski, K Kawakami, K Piper, K Piper, K Skouloudaki, KJ Gaulton, KM Petzold, KS Zaret, L Elghazi, L Pasquali, M Borowiak, M Carrasco, M Gannon, MA Maestro, MC Whitlock, MF Offield, MJL de Hoon, MN Weedon, MP Creyghton, N Bardeesy, N Gao, NM George, P Jacquemin, PA Seymour, R O’Rahilly, R Xie, RE Jennings, RF Luco, S Gupta, S Heinz, S Xuan, T Derrien, T Jowett, W Zhang, WA Whyte, Y Fujitani, Y Liu-Chittenden   +67 more
core   +2 more sources

Muc5ac mucin expression during rat skin development [PDF]

, 2015
Some mucin genes have been detected during human embryonic and fetal organ development; however, little is known about mucin expression in epidermal development, neither in humans nor in other species. The present research was developed to explore Muc5ac
Barbeito, Claudio Gustavo, Croce, María Virginia, Ferretti, Valeria, Segal Eiras, Amada   +3 more
core   +2 more sources

Identification of hub genes, signaling pathways and immune infiltration of recurrent spontaneous abortion based on bioinformatics analysis with clinical verification

Taiwanese Journal of Obstetrics & Gynecology, 2022
Objective: The present study was aimed to identify hub genes associated with recurrent spontaneous abortion (RSA) via both bioinformatics analysis and clinical verification, also to evaluate the related pathways and immune infiltration situation of RSA ...
Yun-Xi Chen, Qian-Qian Zhang, Chang Ge, Jing Yang   +3 more
doaj   +1 more source

Synthesis and maintenance of lipid droplets are essential for mouse preimplantation embryonic development

Development, 2019
Lipid droplets (LDs), which are ubiquitous organelles consisting of a neutral lipid core coated with a phospholipid monolayer, play key roles in the regulation of cellular lipid metabolism.
Ryutaro Aizawa, Megumi Ibayashi, T. Tatsumi, Atsushi Yamamoto, T. Kokubo, N. Miyasaka, Ken Sato, S. Ikeda, N. Minami, Satoshi Tsukamoto   +9 more
semanticscholar   +1 more source

Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors

Nature Communications, 2018
A role for Slit/Robo signalling in pancreas development has not been defined. Here, the authors generate Robo1/Robo2 knockout mice to identify both as needed for establishing initial pancreatic cell identity as well as for proliferation and survival of ...
Sophie Escot, David Willnow, Heike Naumann, Silvia Di Francescantonio, Francesca M. Spagnoli   +4 more
doaj   +1 more source

Ret kinase-mediated mechanical induction of colon stem cells by tumor growth pressure stimulates cancer progression in vivo

Communications Biology, 2022
Ho-Bouldoires, Sollier, Zamfirov and Broders-Bondon et al. show that high frequency pulsatile mechanical stresses maintain the physiological level of mice colon stem cells through the mechanosensitive Ret kinase and that Ret activation is elevated in ...
Thanh Huong Nguyen Ho-Bouldoires, Kévin Sollier, Laura Zamfirov, Florence Broders-Bondon, Démosthène Mitrossilis, Sebastian Bermeo, Coralie L. Guerin, Anna Chipont, Gabriel Champenois, Renaud Leclère, Nicolas André, Laurent Ranno, Aude Michel, Christine Ménager, Didier Meseure, Charlie Demené, Mickael Tanter, Maria Elena Fernández-Sánchez, Emmanuel Farge   +18 more
doaj   +1 more source