Results 41 to 50 of about 1,153,497 (356)

Identification of early onset pre-eclampsia related key genes via bioinformatic analysis

Informatics in Medicine Unlocked, 2022
Background: Pre-eclampsia is a common pregnancy-specific disease. In this study, we used comprehensive bioinformatics to screen key genes related to the development of pre-eclampsia and explore their potential connections. Methods: Two data sets GSE44711
Zhengrui Huang, Ruiping Chen, Yixuan Zhou, Yiling Wei, Haixia Liu, Ping Zhang, Jingyun Wang, Yuzhen Ding, Xiaofeng Yang, Lu Sun, Meiting Shi, Yudie Gao, Ruiman Li   +12 more
doaj   +1 more source

Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial Development. [PDF]

, 2018
RationaleMutations in the transcription factor TBX20 (T-box 20) are associated with congenital heart disease. Germline ablation of Tbx20 results in abnormal heart development and embryonic lethality by embryonic day 9.5.
Aneas, Ivy, Bogomolovas, Julius, Boogerd, Cornelis J, Chen, Ju, Evans, Sylvia M, Joslin, Amelia C, Montefiori, Lindsey, Nobrega, Marcelo A, Sakabe, Noboru, Sobreira, Debora R, Zhang, Lunfeng, Zhou, Bin, Zhu, Xiaoming   +12 more
core   +2 more sources

Inhibition of DRP1 Impedes Zygotic Genome Activation and Preimplantation Development in Mice

Frontiers in Cell and Developmental Biology, 2021
Mitochondrion plays an indispensable role during preimplantation embryo development. Dynamic-related protein 1 (DRP1) is critical for mitochondrial fission and controls oocyte maturation.
Yuanyuan Li, Ning-Hua Mei, Gui-Ping Cheng, Jing Yang, Li-Quan Zhou   +4 more
doaj   +1 more source

Mechanobiology of Embryonic Limb Development [PDF]

Annals of the New York Academy of Sciences, 2007
Abstract:  Considerable evidence exists to support the hypothesis that mechanical forces have an essential role in healthy embryonic skeletal development. Clinical observations and experimental data indicate the importance of muscle contractions for limb development.
Prendergast, Patrick, NOWLAN, NIAMH CATHERINE, MURPHY, PAULA   +2 more
openaire   +4 more sources

Characterizing the zebrafish organizer: microsurgical analysis at the early-shield stage [PDF]

, 1996
The appearance of the embryonic shield, a slight thickening at the leading edge of the blastoderm during the formation of the germ ring, is one of the first signs of dorsoventral polarity in the zebrafish embryo.
Fraser, Scott E., Shih, John
core  

Pre-implantation mouse embryos cultured In vitro under different oxygen concentrations show altered ultrastructures [PDF]

, 2020
Assisted Reproductive Technologies routinely utilize different culture media and oxygen (O2) concentrations to culture human embryos. Overall, embryos cultured under physiological O2 tension (5%) have improved development compared to embryos cultured ...
Antonouli, S, Belli, M, Macchiarelli, G, Nottola, Sa, Palmerini, Mg, Rinaudo, P, Ruggeri, E   +6 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

MiR-322-5p is involved in regulating chondrocyte proliferation and differentiation in offspring’s growth plate of maternal gestational diabetes

Scientific Reports
Pregestational diabetes mellitus (PGDM) has an impact on fetal bone formation, but the underlying mechanism is still obscure. Although miRNAs have been extensively investigated throughout bone formation, their effects on fetal bone development caused by ...
Fan Qian, Xianlong Chen, Simiao Wang, Yeyin Zhong, Min Liu, Guang Wang, Xuesong Yang, Xin Cheng   +7 more
doaj   +1 more source

Development of extra-embryonic membranes and fluid compartments [PDF]

, 2001
An account of the development of extra-embryonic membranes in the embryo of poultry. The roles of these membranes in the transfer of water from albumen to yolk and to embryonic tissue is ...
Baggott, Glenn K.
core  

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source