Results 61 to 70 of about 1,228,315 (316)

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Identification of hub genes, signaling pathways and immune infiltration of recurrent spontaneous abortion based on bioinformatics analysis with clinical verification

Taiwanese Journal of Obstetrics & Gynecology, 2022
Objective: The present study was aimed to identify hub genes associated with recurrent spontaneous abortion (RSA) via both bioinformatics analysis and clinical verification, also to evaluate the related pathways and immune infiltration situation of RSA ...
Yun-Xi Chen, Qian-Qian Zhang, Chang Ge, Jing Yang   +3 more
doaj  

A comparative analysis of transcription factor expression during metazoan embryonic development [PDF]

, 2013
During embryonic development, a complex organism is formed from a single starting cell. These processes of growth and differentiation are driven by large transcriptional changes, which are following the expression and activity of transcription factors (TFs).
arxiv   +1 more source

Embryonic development. [PDF]

, 1930
Publication authorized April 29, 1930.Includes bibliographical references (pages 33-34)
Turner, C. W. (Charles Wesley), 1897-1975
core  

Requirement for DNA Ligase IV during Embryonic Neuronal Development [PDF]

, 2011
The embryonic ventricular and subventricular zones (VZ/SVZ) contain the neuronal stem and progenitor cells and undergo rapid proliferation. The intermediate zone (IZ) contains nonreplicating, differentiated cells.
Carr, Antony M, Gatz, Susanne A, Gruber, Ralph, Hoffmann, Eva, Jeggo, Penny A, Ju, Limei, Liu, Cong, Wang, Zhao-Qi   +7 more
core   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Association between mental health and male fertility: depression, rather than anxiety, is linked to decreased semen quality

Frontiers in Endocrinology
BackgroundInfertility is increasingly recognized as a global health issue affecting couples of reproductive age, with male factors contributing to approximately 50% of infertility cases.
Yi Zhang, Yi Zhang, Bei Chen, Bei Chen, Yaqin Wang, Yaqin Wang, Cong Liu, Cong Liu, Jiayi Sun, Jiayi Sun, Zhimo Zhang, Zhimo Zhang, Liangzi Guan, Liangzi Guan, Ke Xiao, Ke Xiao, Ke Xiao, Zhonghai Zhu, Jin Luo, Jin Luo   +19 more
doaj   +1 more source

Mechanotransductive cascade of Myo-II-dependent mesoderm and endoderm invaginations in embryo gastrulation

Nature Communications, 2017
Mechanical signals regulate tissue differentiation but how this triggers downstream biochemical signals is unclear. Here, the authors place micro-magnets in theDrosophilaembryonic epithelia and show this triggers apical pulsations, in turn stabilizing ...
Démosthène Mitrossilis, Jens-Christian Röper, Damien Le Roy, Benjamin Driquez, Aude Michel, Christine Ménager, Gorky Shaw, Simon Le Denmat, Laurent Ranno, Frédéric Dumas-Bouchiat, Nora M. Dempsey, Emmanuel Farge   +11 more
doaj   +1 more source

International cooperation and the challenge of internet accessibility in Caribbean territories: example of a collaborative platform between the University Hospital of Martinique and Ramón González Coro Hospital in Cuba, through the French PRPH-3 program

BMC Medical Education, 2023
Background Martinique shares with the other Caribbean countries specific public health issues, particularly in the diagnostic and therapeutic management of cancer patients.
Rémi Houpert, Thierry Almont, Christian Mésenge, Line Kleinebreil, Laurence Forlini, Bruno Magnone, Vincent Leroux, Mylène Vestris, Christelle Montabord, Jaylin Carmenate, Yaima Galán, Maria Caredad Rubio, Rodolfo Enriquez, Carol Burte, Nicolas Gatimel, Louis Bujan, Norelyakin Kara, Olivier Edwige, Éric Huyghe, Clarisse Joachim, Jacqueline Véronique-Baudin   +20 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source